[https://www.prophecymarketinsights.com/market_insight/Global-Subcutaneous-Biologics-Market-By-83 Subcutaneous] injection may also be used by people to (self-)administer [[Recreational drug use|recreational drugs]]. This can be referred to as [[skin popping]].<ref name="neph2016">{{cite journal |last1=Lejmi |first1=Hiba |last2=Jen |first2=Kuang-Yu |last3=Olson |first3=Jean L. |last4=James |first4=Sam H. |last5=Sam |first5=Ramin |name-list-style=vanc |title=Characteristics of AA amyloidosis patients in San Francisco: AA amyloidosis |journal=Nephrology |date=April 2016 |volume=21 |issue=4 |pages=308–313 |doi=10.1111/nep.12616|pmid=26370715 |s2cid=31760853 }}</ref> In some cases, the administration of illicit drugs in this way is associated with unsafe practices leading to infections and other adverse effects. In rare cases, this results in serious side effects such as [[AA amyloidosis]].<ref name="neph2016" /> Recreational drugs reported to be administered subcutaneously have included [[cocaine]],<ref>{{cite journal |last1=Khan |first1=Fahd |last2=Mukhtar |first2=Saheel |last3=Anjum |first3=Faqar |last4=Tripathi |first4=Bharati |last5=Sriprasad |first5=Seshadri |last6=Dickinson |first6=Ian K. |last7=Madaan |first7=Sanjeev |name-list-style=vanc |display-authors=6 |title=Fournier's Gangrene Associated with Intradermal Injection of Cocaine |journal=The Journal of Sexual Medicine |date=April 2013 |volume=10 |issue=4 |pages=1184–1186 |doi=10.1111/jsm.12055|pmid=23347293 }}</ref> [[mephedrone]],<ref>{{cite journal |last1=Meng |first1=H |last2=Cao |first2=J |last3=Kang |first3=J |last4=Ying |first4=X |last5=Ji |first5=J |last6=Reynolds |first6=W |last7=Rampe |first7=D |name-list-style=vanc |display-authors=6 |title=Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat. |journal=Toxicology Letters |date=5 January 2012 |volume=208 |issue=1 |pages=62–8 |doi=10.1016/j.toxlet.2011.10.010 |pmid=22037396}}</ref> and [[amphetamine]] derivatives such as [[para-Methoxy-N-methylamphetamine|PMMA]].<ref>{{cite journal |last1=Steele |first1=TD |last2=Katz |first2=JL |last3=Ricaurte |first3=GA |title=Evaluation of the neurotoxicity of N-methyl-1-(4-methoxyphenyl)-2-aminopropane (para-methoxymethamphetamine, PMMA). |journal=Brain Research |date=4 September 1992 |volume=589 |issue=2 |pages=349–52 |doi=10.1016/0006-8993(92)91298-s |pmid=1382813|s2cid=232653 }}</ref>
