Cloning vector: Difference between revisions

[[Cosmids]] are plasmids that incorporate a segment of bacteriophage λ DNA that has the cohesive end site (''cos'') which contains elements required for packaging DNA into λ particles.Under apt origin of replication (ori), it can replicate as a plasmid It is normally used to clone large DNA fragments between 28 and 45 Kb.<ref name="methods in molbio">{{cite book |author=Andrew Preston |title= E. coli plasmid vectors |series=Methods in Molecular Biology |volume=235 |pages=19–20 |url=https://docs.google.com/viewer?a=v&q=cache:e_Vos_9e4KcJ:www.springer.com/cda/content/document/cda_downloaddocument/9781588291516-c2.pdf%3FSGWID%3D0-0-45-434072-p173728492+cloning+vector&hl=en&gl=uk&pid=bl&srcid=ADGEEShmHcr5_CxDFoW6O8WVbsnil4iCHP3dQ-aL-lSqEZEdk7oOQ0cbPQtcaIgx3swAnR0-XT9m56HghNat3vvA6S3SRACpCZKHpV2Y9S2KjSevW-L6P18dZjAXA_cv5vW7BlMZagY_&sig=AHIEtbQskbuShp86-Pg4Xc6qGdqOXi-Hyw |isbn=978-1-58829-151-6 |date= 2003-07-03 }}</ref>