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→The evolution of human centromere 6: This doesn't just magically happen: how did this become known?? Tags: Mobile edit Mobile web edit Advanced mobile edit |
→The evolution of human centromere 6: More remarks; this paragraph is not really up to Wikipedia standards; it feels written for subject matter experts Tags: Mobile edit Mobile web edit Advanced mobile edit |
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== The evolution of human centromere 6 ==
The [[centromere]] of chromosome 6 illustrates an interesting{{to whom}} example of centromere evolution. It was known{{explain}} that in a [[Catarrhini]] ancestor the chromosome 6 centromere was situated near position 26 Mb of the modern human chromosome. In ''Macaca mulatta'', this old centromere went defunct and repositioned to a different chromosomal location{{relevance}}. In case of humans, the old centromere went defunct and a more recent form emerged near the modern position of human cen6 (size of 60 Mb). Such cases are known as Evolutionary New Centromeres (ENC). This assembly phenomenon of the human chromosome 6 gives researchers an opportunity to investigate the origin of the ENC on chromosome 6. <ref>{{Cite journal |last1=Altemose |first1=Nicolas |last2=Logsdon |first2=Glennis A. |last3=Bzikadze |first3=Andrey V. |last4=Sidhwani |first4=Pragya |last5=Langley |first5=Sasha A. |last6=Caldas |first6=Gina V. |last7=Hoyt |first7=Savannah J. |last8=Uralsky |first8=Lev |last9=Ryabov |first9=Fedor D. |last10=Shew |first10=Colin J. |last11=Sauria |first11=Michael E. G. |last12=Borchers |first12=Matthew |last13=Gershman |first13=Ariel |last14=Mikheenko |first14=Alla |last15=Shepelev |first15=Valery A. |date=April 2022 |title=Complete genomic and epigenetic maps of human centromeres |journal=Science |language=en |volume=376 |issue=6588 |pages=eabl4178 |doi=10.1126/science.abl4178 |issn=0036-8075 |pmc=9233505 |pmid=35357911}}</ref>
==Genes==
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