Bis(2-ethylhexyl) phthalate: Difference between revisions

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→‎Use in medical devices: reference to SCHER statement regarding TDI
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===Use in medical devices===
DEHP has been used as a plasticiser in [[medical device]]s such as intravenous tubing and bags, catheters, nasogastric tubes, dialysis bags and tubing, and blood bags and transfusion tubing, and air tubes. For this reason, concern has been expressed about leachates transported into the patient, especially for those requiring extensive infusions, e.g. [[newborn]]s in [[Neonatal intensive care unit|intensive care nursery]] settings, [[hemophilia]]cs, and [[kidney dialysis]] patients. According to the European Commission [[Scientific Committee on Health and Environmental Risks]] (SCHER), exposure to DEHP may exceed the tolerable daily intake in some specific population groups, namely people exposed through medical procedures such as kidney dialysis.<ref>{{cite web | title=Phthalates in school supplies| publisher=GreenFacts Website | accessdate=2009-06-10 | url= http://copublications.greenfacts.org/en/phthalates-school-supplies/}}</ref> The [[American Academy of Pediatrics]] has advocated not to use medical devices that can leach DEHP into patients and , instead, to resort to DEHP-free alternatives.{{Fact|date=January 2008}} In July 2002, the U.S. FDA issued a [http://www.fda.gov/cdrh/safety/dehp.html Public Health Notification] on DEHP, stating in part, "We recommend considering such alternatives when these high-risk procedures are to be performed on male neonates, pregnant women who are carrying male fetuses, and peripubertal males" noting that the alternatives were to look for non-DEHP exposure solutions. The Documentary CBC The Disappearing Male raised concerns about sexual development in male fetal development, miscarriage as DEHP is a pseudo-estrogen and a hormone modifier found in most plastic products such as PVC, polycarbonate, nearly all cosmetic chemical products and many others as a cause of dramatically lower sperm counts in men.
 
===Metabolism===