Calycosin

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Calycosin is a O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus[1] and Trifolium pratense (red clover)[2].

Calycosin
Chemical structure of calycosin
Names
IUPAC name
7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
Other names
7,3'-dihydroxy-4'-methoxyisoflavone
3',7-dihydroxy-4'-methoxyisoflavone
3'-hydroxyformononetin
Identifiers
3D model (JSmol)
ECHA InfoCard 100.222.904 Edit this at Wikidata
  • COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O
Properties
C16H12O5
Molar mass 284.26 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Biosynthesis

Isoflavone 3'-hydroxylase uses formononetin, NADPH, H+ and O2 to produce calycosin, NADP+ and H2O.

References