Calycosin is a O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus[1] and Trifolium pratense (red clover).[2]
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| Names | |
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| IUPAC name
7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
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| Other names
7,3'-dihydroxy-4'-methoxyisoflavone
3',7-dihydroxy-4'-methoxyisoflavone 3'-hydroxyformononetin | |
| Identifiers | |
3D model (JSmol)
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| ECHA InfoCard | 100.222.904 |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C16H12O5 | |
| Molar mass | 284.26 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Biosynthesis
Isoflavone 3'-hydroxylase uses formononetin, NADPH, H+ and O2 to produce calycosin, NADP+ and H2O.
References
- ^ Preparative isolation and purification of calycosin from Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by high-speed counter-current chromatography. Xiaofeng Ma, Tianyou Zhang, Yun Wei, Pengfei Tu, Yingjie Chen and Yoichiro Ito, Journal of Chromatography A, Volume 962, Issues 1-2, 12 July 2002, Pages 243-247
- ^ Identification of isoflavones calycosin and pseudobaptigenin in Trifolium pratense. David R. Biggs and Geoffrey A. Lane, Phytochemistry, Volume 17, Issue 9, 1978, Pages 1683-1684