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Events
- Johann Sebastian Bach examines the organ at the Johanniskirche, Leipzig
- March 23 – English premiere of Handel's Messiah in London
- 1743–1746 Bach revises his St Matthew Passion (two organs used again, but Viola da gamba still retained; Recitatives revised so that now only the vox Christi recitatives have sustained Continuo parts). No evidence of version being performed (version we know today).
Classical music
- George Frideric Handel
- Samson (oratorio)
- Semele (oratorio)
Opera
- Bernard de Bury – Les Caractères de la folie
- Baldassare Galuppi – Enrico
Births
- February 19 – Luigi Boccherini, composer (died 1805)
- May 21 – François Duval, dancer
- July 6 – Valentin Adamberger, operatic tenor (died 1804)
- September 30 – Christian Ehregott Weinlig, cantor and composer (died 1813)
- October 5 – Giuseppe Gazzaniga, composer (died 1818)
- October 10 – Marie-Madeleine Guimard, ballerina (died 1816)
Deaths
- February 1 – Giuseppe Ottavio Pitoni (born 1657)
- February 6 – Toussaint Bertin de la Doué, composer (born 1680)
- February 7 – Lodovico Giustini, composer (born 1685)
- March 16 – Jean-Baptiste Matho, composer (born 1663)
- July 12 – Johann Bernhard Bach (the younger), organist and composer (born 1700)
- September 14 – Georg von Bertouch, composer (born 1668)