2-Ketoarginine methyltransferase (EC 2.1.1.243, mrsA (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:5-carbamimidamido-2-oxopentanoate S-methyltransferase.[1] This enzyme catalyses the following chemical reaction
| 2-Ketoarginine methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.243 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- S-adenosyl-L-methionine + 5-guanidino-2-oxopentanoate S-adenosyl-L-homocysteine + 5-guanidino-3-methyl-2-oxopentanoate
The enzyme is involved in production of the rare amino acid 3-methylarginine.
References
edit- ^ Braun SD, Hofmann J, Wensing A, Ullrich MS, Weingart H, Völksch B, Spiteller D (April 2010). "Identification of the biosynthetic gene cluster for 3-methylarginine, a toxin produced by Pseudomonas syringae pv. syringae 22d/93". Applied and Environmental Microbiology. 76 (8): 2500–8. doi:10.1128/aem.00666-09. PMC 2849186. PMID 20190091.
External links
edit- 2-ketoarginine+methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
