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{{short description|Virologist known for working with Ebola}}
{{short description|Virologist known for working with Ebola}}
{{Infobox scientist
{{Infobox scientist
| name = Jean-Jacques Muyembe
| name = Jean-Jacques Muyembe
| birth_name = Jean-Jacques Muyembe-Tamfum
| birth_name = Jean-Jacques Muyembe-Tamfum
|image = Jean-Jacques Muyembe-Tamfum - 2018 (cropped).jpg
| image = Jean-Jacques Muyembe-Tamfum - 2018 (cropped).jpg
|image_size = 240px
| image_size = 240px
|caption =
| caption =
| workplaces = [[Democratic Republic of the Congo]]<br>National Institute for Biomedical Research
| workplaces = [[Democratic Republic of the Congo]]<br/>National Institute for Biomedical Research
| thesis_title =Mode d'action des inducteurs d'interferon non-viraux dans une infection virale de la souris
| thesis_title = Mode d'action des inducteurs d'interferon non-viraux dans une infection virale de la souris
| thesis_url = https://www.worldcat.org/oclc/314202292
| thesis_url = https://www.worldcat.org/oclc/314202292
| thesis_year = 1973
| thesis_year = 1973
| alma_mater = [[Université catholique de Louvain|University of Leuven]] (PhD)<br> [[Lovanium University]]
| alma_mater = [[Université catholique de Louvain|University of Leuven]] (PhD)<br/> [[Lovanium University]]
| known_for = Ebola Prevention & Treatment
| known_for = Ebola discovery,<ref name=":6" /> prevention & treatment
| awards = [[Nature's 10]] (2019)<ref name=n10/><br>[[Royal Society Africa Prize]] (2015)
| awards = [[Nature's 10|''Nature''{{'s}} 10]] (2019)<ref name=n10/><br />[[Hideyo Noguchi Africa Prize]] (2019)<br/>[[Royal Society Africa Prize]] (2015)
}}
}}


'''Jean-Jacques Muyembe''' is a Congolese microbiologist. He is the General Director of the [[Democratic Republic of the Congo]] [[Institut National pour la Recherche Biomedicale]] (''INRB''). He was part of team at the [[Yambuku]] Catholic Mission Hospital that investigated the first [[Ebola outbreak]], and was part of the effort that discovered Ebola as a new disease, although his exact role is still subject to controversy.<ref name=":6">{{Cite web|url=https://www.npr.org/sections/goatsandsoda/2019/11/04/774863495/this-congolese-doctor-discovered-ebola-but-never-got-credit-for-it-until-now|title=This Congolese Doctor Discovered Ebola But Never Got Credit For It — Until Now|website=NPR.org|language=en|access-date=2019-11-05}}</ref><ref name="Breman et al 2016">{{cite journal |last1=Breman |first1=Joel G. |last2=Heymann |first2=David L. |last3=Lloyd |first3=Graham |last4=McCormick |first4=Joseph B. |last5=Miatudila |first5=Malonga |last6=Murphy |first6=Frederick A. |last7=Muyembé-Tamfun |first7=Jean-Jacques |last8=Piot |first8=Peter |last9=Ruppol |first9=Jean-François |last10=Sureau |first10=Pierre |last11=van der Groen |first11=Guido |last12=Johnson |first12=Karl M. |title=Discovery and Description of Ebola Zaire Virus in 1976 and Relevance to the West African Epidemic During 2013–2016 |journal=Journal of Infectious Diseases |date=15 October 2016 |volume=214 |issue=suppl 3 |pages=S93–S101 |doi=10.1093/infdis/jiw207 }}</ref> In 2016, he led the research that designed, along with other researchers at the INRB and the [[National Institute of Health]] [[Vaccine Research Center]] in the US, one of the most promising[[Ebola virus disease treatment research| treatment for Ebola]], [[mAb114]], working .<ref name=":7">{{cite journal | vauthors = Corti D, Misasi J, Mulangu S, Stanley DA, Kanekiyo M, Wollen S, Ploquin A, Doria-Rose NA, Staupe RP, Bailey M, Shi W, Choe M, Marcus H, Thompson EA, Cagigi A, Silacci C, Fernandez-Rodriguez B, Perez L, Sallusto F, Vanzetta F, Agatic G, Cameroni E, Kisalu N, Gordon I, Ledgerwood JE, Mascola JR, Graham BS, Muyembe-Tamfun JJ, Trefry JC, Lanzavecchia A, Sullivan NJ | display-authors = 6 | title = Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody | journal = Science | volume = 351 | issue = 6279 | pages = 1339–42 | date = March 2016 | pmid = 26917593 | doi = 10.1126/science.aad5224 | bibcode = 2016Sci...351.1339C | doi-access = free }}</ref>. The treatment was successfully experimented during recent outbreaks in the DRC<ref>For the first time, clinical trial results show Ebola drugs improve survival rates. https://www.statnews.com/2019/08/12/for-the-first-time-clinical-trial-results-show-ebola-drugs-improve-survival-rates/</ref>, on the express decision of the then DRC Minister of Health, Dr Oly Ilunga, despite a prior negative advice from the World Health Organization.<ref>Ebola outbreak opens way to chaotic jockeying to test experimental drugs. https://www.statnews.com/2018/05/30/ebola-experimental-treatments/</ref>
'''Jean-Jacques Muyembe''' is a Congolese microbiologist. He is the general director of the [[Democratic Republic of the Congo]] [[Institut National pour la Recherche Biomedicale]] (''INRB''). He was part of team at the [[Yambuku]] Catholic Mission Hospital that investigated the first [[Ebola outbreak]], and was part of the effort that discovered Ebola as a new disease, although his exact role is still subject to controversy.<ref name=":6">{{Cite web|url=https://www.npr.org/sections/goatsandsoda/2019/11/04/774863495/this-congolese-doctor-discovered-ebola-but-never-got-credit-for-it-until-now|title=This Congolese Doctor Discovered Ebola But Never Got Credit For It — Until Now|website=NPR.org|language=en|access-date=2019-11-05}}</ref><ref name="Breman et al 2016">{{cite journal |last1=Breman |first1=Joel G. |last2=Heymann |first2=David L. |last3=Lloyd |first3=Graham |last4=McCormick |first4=Joseph B. |last5=Miatudila |first5=Malonga |last6=Murphy |first6=Frederick A. |last7=Muyembé-Tamfun |first7=Jean-Jacques |last8=Piot |first8=Peter |last9=Ruppol |first9=Jean-François |last10=Sureau |first10=Pierre |last11=van der Groen |first11=Guido |last12=Johnson |first12=Karl M. |title=Discovery and Description of Ebola Zaire Virus in 1976 and Relevance to the West African Epidemic During 2013–2016 |journal=Journal of Infectious Diseases |date=15 October 2016 |volume=214 |issue=suppl 3 |pages=S93–S101 |doi=10.1093/infdis/jiw207 |pmid=27357339 |pmc=5050466 }}</ref> In 2016, he led the research that designed, along with other researchers at the INRB and the [[National Institute of Health]] [[Vaccine Research Center]] in the US, one of the most promising [[Ebola virus disease treatment research|treatment for Ebola]], [[mAb114]].<ref name=pmid26917593>{{cite journal | vauthors = Corti D, Misasi J, Mulangu S, Stanley DA, Kanekiyo M, Wollen S, Ploquin A, Doria-Rose NA, Staupe RP, Bailey M, Shi W, Choe M, Marcus H, Thompson EA, Cagigi A, Silacci C, Fernandez-Rodriguez B, Perez L, Sallusto F, Vanzetta F, Agatic G, Cameroni E, Kisalu N, Gordon I, Ledgerwood JE, Mascola JR, Graham BS, Muyembe-Tamfun JJ, Trefry JC, Lanzavecchia A, Sullivan NJ | display-authors = 6 | title = Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody | journal = Science | volume = 351 | issue = 6279 | pages = 1339–42 | date = March 2016 | pmid = 26917593 | doi = 10.1126/science.aad5224 | bibcode = 2016Sci...351.1339C | doi-access = free }}</ref> The treatment was successfully experimented during recent outbreaks in the DRC,<ref>{{cite news |title=For the first time, clinical trial data show Ebola drugs improve survival rates |url=https://www.statnews.com/2019/08/12/for-the-first-time-clinical-trial-results-show-ebola-drugs-improve-survival-rates/ |work=STAT |date=12 August 2019 }}</ref> on the express decision of the then DRC Minister of Health, Dr Oly Ilunga, despite a prior negative advice from the World Health Organization.<ref>{{cite news |title=Ebola outbreak opens way to chaotic jockeying to test experimental drugs |url=https://www.statnews.com/2018/05/30/ebola-experimental-treatments/ |work=STAT |date=30 May 2018 }}</ref>


== Early life and education ==
== Early life and education ==
Muyembe grew up in [[Bandundu Province]], the child of farmers. He was educated in schools run by [[Jesuits]]. He studied medicine, starting in 1962, at the [[Lovanium University]] in the [[Belgian Congo]] ([[Democratic Republic of the Congo]]) where he became interested in microbiology and graduated in 1969.<ref name=":0">{{Cite web|url=https://www.who.int/csr/disease/ebola/advisory-groups/bio-muyembe/en/|title=WHO {{!}} Jean-Jacques Muyembe|website=WHO|access-date=2018-12-21}}</ref> He earned a PhD in virology at the [[Université catholique de Louvain|University of Leuven]] in Belgium, working on [[viral infection]]s with mouse models.<ref name=":0" /><ref name=":1">{{Cite journal|url=http://www.who.int/bulletin/volumes/96/12/18-031218/en/|title=WHO {{!}} Jean-Jacques Muyembe Tamfum: a life's work on Ebola|volume=96|issue=12|pages=804–805|journal=Bulletin of the World Health Organization|access-date=2018-12-21|doi=10.2471/BLT.18.031218|pmid=30505027|pmc=6249701|year=2018}}</ref> He returned to [[Zaire]] ([[Democratic Republic of the Congo]]) in 1973 and worked in outbreak control.<ref name=":2">{{cite journal |doi=10.1016/S0140-6736(15)61128-X |pmid=26122060 |title=Jean-Jacques Muyembe-Tamfum: Africa's veteran Ebola hunter |journal=The Lancet |volume=385 |issue=9986 |pages=2455 |year=2015 |last1=Honigsbaum |first1=Mark }}</ref> In 1974 there was a [[cholera]] outbreak in [[Matadi]], which was the first crisis that Muyembe worked on.<ref name=":1" />
Muyembe grew up in [[Bandundu Province]], the child of farmers. He was educated in schools run by [[Jesuits]]. He studied medicine, starting in 1962, at the [[Lovanium University]] in the [[Belgian Congo]] ([[Democratic Republic of the Congo]]) where he became interested in microbiology and graduated in 1969.<ref name=":0">{{Cite web|url=https://www.who.int/csr/disease/ebola/advisory-groups/bio-muyembe/en/|archive-url=https://web.archive.org/web/20150717063944/http://www.who.int/csr/disease/ebola/advisory-groups/bio-muyembe/en/|url-status=dead|archive-date=July 17, 2015|title=Jean-Jacques Muyembe|website=WHO|access-date=2018-12-21}}</ref> He earned a PhD in virology at the [[Université catholique de Louvain|University of Leuven]] in Belgium, working on [[viral infection]]s with mouse models.<ref name=":0" /><ref name=pmid30505027>{{cite journal |title=Jean-Jacques Muyembe Tamfum: a life's work on Ebola |journal=Bulletin of the World Health Organization |date=1 December 2018 |volume=96 |issue=12 |pages=804–805 |doi=10.2471/BLT.18.031218 |pmid=30505027 |pmc=6249701 }}</ref> He returned to [[Zaire]] ([[Democratic Republic of the Congo]]) in 1973 and worked in the cholera outbreak control.<ref name=pmid26122060>{{cite journal |last1=Honigsbaum |first1=Mark |title=Jean-Jacques Muyembe-Tamfum: Africa's veteran Ebola hunter |journal=The Lancet |date=June 2015 |volume=385 |issue=9986 |pages=2455 |doi=10.1016/S0140-6736(15)61128-X |pmid=26122060 |s2cid=25547601 }}</ref> In 1974 there was a [[cholera]] outbreak in [[Matadi]], which was the first crisis that Muyembe worked on.<ref name=pmid30505027/>


== Career ==
== Career ==
[[File:Ebola Virus - Electron Micrograph.tiff|thumb|Scanning electron micrograph of the [[Ebola virus]] in an [[African green monkey kidney cell]]]]
[[File:Ebola Virus - Electron Micrograph.tiff|thumb|Scanning electron micrograph of the [[Ebola virus]] in an [[African green monkey kidney cell]]]]
Muyembe was described by ''[[The Lancet]]'' as ''Africa's Ebola hunter''.<ref name=":2" /> He first came across [[ebola virus]] in 1976 at a Belgian hospital in [[Yambuku]].<ref name=":2" /><ref>{{cite journal |doi=10.7554/eLife.09015 |pmid=26525597 |pmc=4629279 |title=Ebola virus disease in Zaire (the Democratic Republic of the Congo), 1976-2014 |journal=eLife |volume=4 |year=2015 |last1=Rosello |first1=Alicia |last2=Mossoko |first2=Mathias |last3=Flasche |first3=Stefan |last4=Van Hoek |first4=Albert Jan |last5=Mbala |first5=Placide |last6=Camacho |first6=Anton |last7=Funk |first7=Sebastian |last8=Kucharski |first8=Adam |last9=Ilunga |first9=Benoit Kebela |last10=Edmunds |first10=W John |last11=Piot |first11=Peter |last12=Baguelin |first12=Marc |last13=Muyembe Tamfum |first13=Jean-Jacques }}</ref> Using a long steel rod, Muyembe took liver biopsies from three nuns who had died, but the results were inconclusive. He was the first scientist to come into contact with the virus and survive.<ref>{{Cite news|url=https://www.huffingtonpost.com/entry/ebola-neglected-tropical-diseases_us_58d2ac02e4b0f838c62e9e0d|title=He Treated The Very First Ebola Cases 40 Years Ago. Then He Watched The World Forget.|date=2017-03-24|newspaper=Huffington Post|access-date=2018-12-21|last1=McNeish|first1=Hannah}}</ref> Muyembe has been described as one of the discoverers of Ebola due to his work in the 1976 outbreak.<ref name=":6" /> He took the blood of a sick nurse, which was sent for analysis at the Institute for Tropical Medicine in [[Antwerp]], then to the [[Centers for Disease Control and Prevention]], where [[Peter Piot]] used the sample to discover Ebola.<ref name=":2" /> That version of events was later refuted in a 2016 scientific article he co-signed with some of the remaining actors of that first epidemic.<ref name="Breman et al 2016"/>
Muyembe was described by ''[[The Lancet]]'' as ''Africa's Ebola hunter''.<ref name=pmid26122060/> He first came across [[Ebola virus]] in 1976 at a Belgian hospital in [[Yambuku]].<ref name=pmid26122060/><ref>{{cite journal |doi=10.7554/eLife.09015 |pmid=26525597 |pmc=4629279 |title=Ebola virus disease in Zaire (the Democratic Republic of the Congo), 1976-2014 |journal=eLife |volume=4 |year=2015 |last1=Rosello |first1=Alicia |last2=Mossoko |first2=Mathias |last3=Flasche |first3=Stefan |last4=Van Hoek |first4=Albert Jan |last5=Mbala |first5=Placide |last6=Camacho |first6=Anton |last7=Funk |first7=Sebastian |last8=Kucharski |first8=Adam |last9=Ilunga |first9=Benoit Kebela |last10=Edmunds |first10=W John |last11=Piot |first11=Peter |last12=Baguelin |first12=Marc |last13=Muyembe Tamfum |first13=Jean-Jacques |doi-access=free }}</ref> Using a long steel rod, Muyembe took liver biopsies from three nuns who had died, but the results were inconclusive. He was the first scientist to come into contact with the virus and survive.<ref>{{Cite news|url=https://www.huffingtonpost.com/entry/ebola-neglected-tropical-diseases_us_58d2ac02e4b0f838c62e9e0d|title=He Treated The Very First Ebola Cases 40 Years Ago. Then He Watched The World Forget.|date=2017-03-24|newspaper=Huffington Post|access-date=2018-12-21|last1=McNeish|first1=Hannah}}</ref> Muyembe has been described as one of the discoverers of Ebola due to his work in the 1976 outbreak.<ref name=":6" /> He took the blood of a sick nurse, which was sent for analysis at the Institute for Tropical Medicine in [[Antwerp]], then to the [[Centers for Disease Control and Prevention]], where [[Peter Piot]] used the sample to discover Ebola.<ref name=pmid26122060/> That version of events, regarding his role in the 1976 outbreak, was later refuted in a 2016 scientific article he co-signed with some of the remaining actors of that first epidemic.<ref name="Breman et al 2016"/>


He was appointed the Dean of the [[University of Kinshasa]] Medical School in 1978.<ref name=":1" /> In 1981 Muyembe joined the [[Institut Pasteur de Dakar]] in [[Senegal]], working with the [[Centers for Disease Control and Prevention]] to study the [[Ebola virus|ebola]] and [[marburg virus]].<ref name=":1" /> In 1998 he was made the Director of the [[Democratic Republic of the Congo]] National Institute for Biomedical Research.<ref name=":5">{{Cite web|url=http://www.icreid.com/speakers/jean-jacques-muyembe-tamfum-md-phd/|title=Jean-Jacques Muyembe-Tamfum, MD, PhD « ICREID|access-date=2018-12-21|archive-url=https://web.archive.org/web/20181222082141/http://www.icreid.com/speakers/jean-jacques-muyembe-tamfum-md-phd/|archive-date=2018-12-22|url-status=dead}}</ref>
He was appointed dean of the [[University of Kinshasa]] Medical School in 1978.<ref name=pmid30505027/> In 1981 Muyembe joined the [[Institut Pasteur de Dakar]] in [[Senegal]], working with the [[Centers for Disease Control and Prevention]] to study the [[Ebola virus|Ebola]] and [[Marburg virus]].<ref name=pmid30505027/> In 1998 he was made the director of the [[Democratic Republic of the Congo]] National Institute for Biomedical Research.<ref name=":5">{{Cite web|url=http://www.icreid.com/speakers/jean-jacques-muyembe-tamfum-md-phd/|title=Jean-Jacques Muyembe-Tamfum, MD, PhD « ICREID|access-date=2018-12-21|archive-url=https://web.archive.org/web/20181222082141/http://www.icreid.com/speakers/jean-jacques-muyembe-tamfum-md-phd/|archive-date=2018-12-22|url-status=dead}}</ref>


He has acted as an adviser to the [[World Health Organization]] Emergency Committee on Ebola.<ref name=":3">{{Cite web|url=https://royalsociety.org/people/jean-jacques-muyembe-tamfum-100000005/|title=Professor Jean-Jacques Muyembe-Tamfum {{!}} Royal Society|website=royalsociety.org|access-date=2018-12-21}}</ref> Here he leads 15 researchers studying [[sleeping sickness]], [[bas-Congo virus]] and the [[Ebola virus disease|ebola]].<ref name=":3" /> He has advised political leadership in [[West Africa]].<ref>{{Cite web|url=https://news.vice.com/en_us/article/3kewvn/the-democratic-republic-of-congo-has-tackled-another-ebola-outbreak|title=How the Democratic Republic of Congo Fought A Different Ebola Outbreak|last=Stokes|first=Elaisha|date=2014-10-24|website=Vice News|access-date=2018-12-21}}</ref>
He has acted as an adviser to the [[World Health Organization]] Emergency Committee on Ebola.<ref name=":3">{{Cite web|url=https://royalsociety.org/people/jean-jacques-muyembe-tamfum-100000005/|title=Professor Jean-Jacques Muyembe-Tamfum {{!}} Royal Society|website=royalsociety.org|access-date=2018-12-21}}</ref> Here he leads 15 researchers studying [[sleeping sickness]], [[bas-Congo virus]] and the [[Ebola virus disease|Ebola]].<ref name=":3" /> He has advised political leadership in [[West Africa]].<ref>{{Cite web|url=https://news.vice.com/en_us/article/3kewvn/the-democratic-republic-of-congo-has-tackled-another-ebola-outbreak|title=How the Democratic Republic of Congo Fought A Different Ebola Outbreak|last=Stokes|first=Elaisha|date=2014-10-24|website=Vice News|access-date=2018-12-21}}</ref>


He recognised the [[Sociocultural context|sociocultural]] challenges of ebola, trying to encourage hospitals improve their infection control and community engagement.<ref name=":2" /> He worked with [[David L. Heymann]] on the [[ebola outbreak]] in 1995.<ref name=":2" /> He was called by the Director of the [[Kikwit]] General Hospital who was asking for help with an outbreak of deadly [[diarrhea]]. When Muyembe arrived, he recognised it was [[Ebola virus disease|ebola]], and sent samples for confirmation at the [[Centers for Disease Control and Prevention]].<ref name=":1" /> He has chaired the international committees that looked to control the [[Ebola outbreak]]s in [[Gabon]] and the [[Democratic Republic of the Congo]].<ref name=":0" /> He leads research into the reservoirs of the [[Ebola virus disease|ebola virus]] in the [[Democratic Republic of the Congo|DRC]].<ref name=":0" /> In 2009, he demonstrated that the [[ebola outbreak]]s in the DRC were due to [[fruit bat]] exposure.<ref>{{cite journal |doi=10.1089/vbz.2008.0167 |pmid=19323614 |title=Human Ebola Outbreak Resulting from Direct Exposure to Fruit Bats in Luebo, Democratic Republic of Congo, 2007 |journal=Vector-Borne and Zoonotic Diseases |volume=9 |issue=6 |pages=723–728 |year=2009 |last1=Leroy |first1=Eric M. |last2=Epelboin |first2=Alain |last3=Mondonge |first3=Vital |last4=Pourrut |first4=Xavier |last5=Gonzalez |first5=Jean-Paul |last6=Muyembe-Tamfum |first6=Jean-Jacques |last7=Formenty |first7=Pierre }}</ref> He has developed an anti-Ebola serum therapy .<ref>{{Cite web|url=http://gdri-ehede.univ-fcomte.fr/spip.php?article42|title=Jean-Jacques Muyembe receives the Christophe Merieux prize - gdri-ehede|website=gdri-ehede.univ-fcomte.fr|access-date=2018-12-21}}</ref> The anti-ebola serum therapy, using antibodies from convalescent patients, was first tried by another medical team during the 1976 outbreak in Yambuku and subsequently recommended for future outbreaks by the International Commission set up by the Government of DRC (formerly Zaïre).<ref>{{cite journal |title=Ebola haemorrhagic fever in Zaire, 1976 |journal=Bulletin of the World Health Organization |date=1978 |volume=56 |issue=2 |pages=271–293 |pmid=307456 |pmc=2395567 }}</ref>
He recognised the [[Sociocultural context|sociocultural]] challenges of Ebola, trying to encourage hospitals improve their infection control and community engagement.<ref name=pmid26122060/> He worked with [[David L. Heymann]] on the [[Ebola outbreak]] in 1995.<ref name=pmid26122060/> He was called by the director of the [[Kikwit]] General Hospital who was asking for help with an outbreak of deadly [[diarrhea]]. When Muyembe arrived, he recognised it was [[Ebola virus disease|Ebola]], and sent samples for confirmation at the [[Centers for Disease Control and Prevention]].<ref name=pmid30505027/> He has chaired the international committees that looked to control the [[Ebola outbreak]]s in [[Gabon]] and the [[Democratic Republic of the Congo]].<ref name=":0" /> He leads research into the reservoirs of the [[Ebola virus disease|Ebola virus]] in the [[Democratic Republic of the Congo|DRC]].<ref name=":0" /> In 2009, he demonstrated that the [[Ebola outbreak]]s in the DRC were due to [[fruit bat]] exposure.<ref>{{cite journal |doi=10.1089/vbz.2008.0167 |pmid=19323614 |title=Human Ebola Outbreak Resulting from Direct Exposure to Fruit Bats in Luebo, Democratic Republic of Congo, 2007 |journal=Vector-Borne and Zoonotic Diseases |volume=9 |issue=6 |pages=723–728 |year=2009 |last1=Leroy |first1=Eric M. |last2=Epelboin |first2=Alain |last3=Mondonge |first3=Vital |last4=Pourrut |first4=Xavier |last5=Gonzalez |first5=Jean-Paul |last6=Muyembe-Tamfum |first6=Jean-Jacques |last7=Formenty |first7=Pierre }}</ref> He has developed an anti-Ebola serum therapy .<ref>{{Cite web|url=http://gdri-ehede.univ-fcomte.fr/spip.php?article42|title=Jean-Jacques Muyembe receives the Christophe Merieux prize - gdri-ehede|website=gdri-ehede.univ-fcomte.fr|access-date=2018-12-21}}</ref> The anti-Ebola serum therapy, using antibodies from convalescent patients, was first tried by another medical team during the 1976 outbreak in Yambuku and subsequently recommended for future outbreaks by the International Commission set up by the Government of DRC (formerly Zaïre).<ref>{{cite journal |title=Ebola haemorrhagic fever in Zaire, 1976 |journal=Bulletin of the World Health Organization |date=1978 |volume=56 |issue=2 |pages=271–293 |pmid=307456 |pmc=2395567 |author1=Report of an International Commission }}</ref>


In 2014, he was appointed by Director General [[Margaret Chan]] to the WHO Advisory Group on the Ebola Virus Disease Response, co-chaired by [[Sam Zaramba]] and [[David L. Heymann]].<ref>[https://www.who.int/csr/disease/ebola/advisory-groups/members/en/ Members of the WHO Advisory Group on the Ebola Virus Disease Response] [[World Health Organization]].</ref>
In 2014, he was appointed by Director General [[Margaret Chan]] to the WHO Advisory Group on the Ebola Virus Disease Response, co-chaired by [[Sam Zaramba]] and [[David L. Heymann]].<ref>[https://web.archive.org/web/20141128154756/http://www.who.int/csr/disease/ebola/advisory-groups/members/en/ Members of the WHO Advisory Group on the Ebola Virus Disease Response] [[World Health Organization]].</ref>


There was a further [[ebola outbreak]] in 2018, which took time to control due to delays in reporting.<ref name=":4">{{Cite web|url=https://www.theatlantic.com/health/archive/2018/05/ebola-outbreak-drc-three-four-months/560237/|title=The New Ebola Outbreak Could Take 'Three, Maybe Four' Months to Control|last=Yong|first=Ed|date=2018-05-11|website=The Atlantic|access-date=2018-12-21}}</ref> The [[Wellcome Trust]] and [[Department for International Development]] donated £1 million each.<ref name=":4" /> He pioneered the use of an experimental [[ebola vaccine]] during the outbreak to limit the spread of the virus, including vaccinating [[health professional]]s.<ref>{{Cite news|url=https://www.bbc.com/afrique/region-44164480|title=Ebola resurgit car nous ne connaissons pas son réservoir|date=2018-05-18|work=BBC News Afrique|access-date=2018-12-21}}</ref><ref>{{cite journal |doi=10.1101/113506 |title=Effect of vaccinating health care workers to control Ebola virus disease: A modelling analysis of outbreak data |year=2018 |last1=Robert |first1=Alexis |last2=Camacho |first2=Anton |last3=Edmunds |first3=W John |last4=Baguelin |first4=Marc |last5=Muyembe Tamfum |first5=Jean-Jacques |last6=Rosello |first6=Alicia |last7=Keita |first7=Sakoba |last8=Eggo |first8=Rosalind M. |doi-access=free }}</ref>. That position on the use of experimental drugs during outbreaks stirred some heated debate in the DRC, with Dr Oly Ilunga eventually resigning from his position as the Minister of Health, citing undue pressure and interference from unamed multinational pharmaceutical firms.<ref> Un an d’Ebola en RDC: qui croire dans la polémique sur le deuxième vaccin? http://www.rfi.fr/fr/afrique/20190802-ebola-rdc-croire-polemique-deuxieme-vaccin</ref>
There was a further [[Ebola outbreak]] in 2018, which took time to control due to delays in reporting.<ref name=":4">{{Cite web|url=https://www.theatlantic.com/health/archive/2018/05/ebola-outbreak-drc-three-four-months/560237/|title=The New Ebola Outbreak Could Take 'Three, Maybe Four' Months to Control|last=Yong|first=Ed|date=2018-05-11|website=The Atlantic|access-date=2018-12-21}}</ref> The [[Wellcome Trust]] and [[Department for International Development]] donated £1 million each.<ref name=":4" /> He pioneered the use of an experimental [[Ebola vaccine]] during the outbreak to limit the spread of the virus, including vaccinating [[health professional]]s.<ref>{{Cite news|url=https://www.bbc.com/afrique/region-44164480|title=Ebola resurgit car nous ne connaissons pas son réservoir|date=2018-05-18|work=BBC News Afrique|access-date=2018-12-21}}</ref><ref>{{cite |doi=10.1101/113506 |title=Effect of vaccinating health care workers to control Ebola virus disease: A modelling analysis of outbreak data |year=2018 |last1=Robert |first1=Alexis |last2=Camacho |first2=Anton |last3=Edmunds |first3=W John |last4=Baguelin |first4=Marc |last5=Muyembe Tamfum |first5=Jean-Jacques |last6=Rosello |first6=Alicia |last7=Keita |first7=Sakoba |last8=Eggo |first8=Rosalind M. |doi-access=free |url=https://www.biorxiv.org/content/biorxiv/early/2018/11/23/113506.full.pdf }}</ref> That position on the use of experimental drugs during outbreaks stirred some heated debate in the DRC, with Dr Oly Ilunga eventually resigning from his position as the Minister of Health, citing undue pressure and interference from unnamed multinational pharmaceutical firms.<ref>Un an d’Ebola en RDC: qui croire dans la polémique sur le deuxième vaccin? http://www.rfi.fr/fr/afrique/20190802-ebola-rdc-croire-polemique-deuxieme-vaccin</ref>


Muyembe has established multiple research facilities, including a [[Poliomyelitis|polio]] and [[influenza]] lab. In 2017 he partnered with the [[Japan International Cooperation Agency]] to build a research complex with several biosafety labs.<ref name=":0" /> As of 2018, the [[Democratic Republic of the Congo|DRC]] still have none of their own labs to test for [[Ebola virus|ebola]].<ref name=":0" />
Muyembe has established multiple research facilities, including a [[Poliomyelitis|polio]] and [[influenza]] lab. In 2017 he partnered with the [[Japan International Cooperation Agency]] to build a research complex with several biosafety labs.<ref name=":0" /> As of 2018, the [[Democratic Republic of the Congo|DRC]] still have none of their own labs to test for Ebola.<ref name=":0" />


On April 3, 2020, during a press conference in Kinshasa, Muyembe advocated for the trial in DRC of experimental vaccines against the Covid-19 virus in the midst of a major pandemic, generating a serious backlash from the congolese population.<ref>DR Congo 'prepared' to take part in vaccine testing: official. by AFP |https://news.yahoo.com/dr-congo-prepared-part-vaccine-testing-official-215705424.html</ref> He eventually backtracked, claiming a misunderstanding.<ref>{{cite web |title=Covid-19 et vaccin en RDC: les précisions Dr Muyembe |url=https://www.youtube.com/watch?v=aGCuywaX4cA }}</ref>
On April 3, 2020, during a press conference in Kinshasa, Muyembe advocated for the trial in DRC of experimental vaccines against the COVID-19 virus in the midst of a major pandemic, generating a serious backlash from the congolese population.<ref>DR Congo 'prepared' to take part in vaccine testing: official. by AFP |https://news.yahoo.com/dr-congo-prepared-part-vaccine-testing-official-215705424.html</ref> He eventually backtracked, claiming a misunderstanding.<ref>{{cite web |title=Covid-19 et vaccin en RDC: les précisions Dr Muyembe | website=[[YouTube]] |url=https://www.youtube.com/watch?v=aGCuywaX4cA }}</ref>


== Awards and honours ==
== Awards and honours ==
In 2015 he was awarded the Christophe Mérieux Prize to study further research in the [[Congo Basin]].<ref name=":2" /><ref>{{Citation|last=Institut de France|title=Jean-Jacques Muyembe Tamfum, lauréat du Prix Christophe Mérieux 2015.|url=https://www.youtube.com/watch?v=3DewCtqUyCA|access-date=2018-12-21}}</ref> That year he was awarded the [[Royal Society Africa Prize]] ''"for his seminal work on viral haemorrhagic fevers, including Ebola, generating the foundation of our understanding of the epidemiology, clinical manifestations and control of outbreaks of these viral infections".''<ref name=":5" /><ref>{{Cite web|url=http://citifmonline.com/2015/08/20/ghanaian-scientist-wins-2015-royal-society-pfizer-early-career-award/|title=Ghanaian scientist wins 2015 Royal Society Pfizer Early Career Award|date=2015-08-20|website=citifmonline.com|access-date=2018-12-21}}</ref><ref>{{Cite book|url=http://royalsociety.org/Pfizer-Award/|title=The Royal Society Pfizer Award|publisher=The Royal Society}}</ref><ref>{{Cite web|url=https://blogs.lshtm.ac.uk/alsfordlab/2015/11/23/royal-society-pfizer-awards-19th-october-2015/|title=Royal Society Pfizer Awards, 19th October 2015 {{!}} Alsford Lab|website=blogs.lshtm.ac.uk|access-date=2018-12-21}}</ref> He was presented with the Lifetime Achievement Award at the 2015 International Symposium on Filoviruses. He was named as one of [[Nature's 10]] in 2018 and 2019.<ref>{{Cite web|url=https://www.nature.com/articles/d41586-018-07683-5|title=Nature's 10|website=www.nature.com|access-date=2018-12-21}}</ref><ref name=n10>{{cite journal |last1=Cyranoski |first1=David |last2=Gaind |first2=Nisha |last3=Gibney |first3=Elizabeth |last4=Masood |first4=Ehsan |last5=Maxmen |first5=Amy |last6=Reardon |first6=Sara |last7=Schiermeier |first7=Quirin |last8=Tollefson |first8=Jeff |last9=Witze |first9=Alexandra |title=Nature’s 10: Ten people who mattered in science in 2019 |journal=Nature |date=17 December 2019 |volume=576 |issue=7787 |pages=361–372 |doi=10.1038/d41586-019-03749-0 |pmid=31848484 |bibcode=2019Natur.576..361C |doi-access=free }}</ref> In 2019 he won the [[Hideyo Noguchi Africa Prize]] from the Government of Japan.<ref>{{cite web|url=https://www.mofa.go.jp/af/af1/page22e_000884.html|title= Laureates of the Third Hideyo Noguchi Africa Prize |publisher=Ministry of Foreign Affairs of Japan|accessdate= 2 October 2019}}</ref>
In 2015, he was awarded the Christophe Mérieux Prize to study further research in the [[Congo Basin]].<ref name=pmid26122060/><ref>{{Citation|last=Institut de France|title=Jean-Jacques Muyembe Tamfum, lauréat du Prix Christophe Mérieux 2015.|url=https://www.youtube.com/watch?v=3DewCtqUyCA|access-date=2018-12-21}}</ref> That year he was awarded the [[Royal Society Africa Prize]] ''"for his seminal work on viral haemorrhagic fevers, including Ebola, generating the foundation of our understanding of the epidemiology, clinical manifestations and control of outbreaks of these viral infections".''<ref name=":5" /><ref>{{Cite web|url=http://citifmonline.com/2015/08/20/ghanaian-scientist-wins-2015-royal-society-pfizer-early-career-award/|title=Ghanaian scientist wins 2015 Royal Society Pfizer Early Career Award|date=2015-08-20|website=citifmonline.com|access-date=2018-12-21}}</ref><ref>{{Cite book|url=http://royalsociety.org/Pfizer-Award/|title=The Royal Society Pfizer Award|publisher=The Royal Society}}</ref><ref>{{Cite web|url=https://blogs.lshtm.ac.uk/alsfordlab/2015/11/23/royal-society-pfizer-awards-19th-october-2015/|title=Royal Society Pfizer Awards, 19th October 2015 {{!}} Alsford Lab|website=blogs.lshtm.ac.uk|date=23 November 2015 |access-date=2018-12-21}}</ref> He was presented with the Lifetime Achievement Award at the 2015 International Symposium on Filoviruses. He was named as one of [[Nature's 10]] in 2018 and 2019.<ref>{{cite journal |last1=Gibney |first1=Elizabeth |last2=Callaway |first2=Ewen |last3=Cyranoski |first3=David |last4=Gaind |first4=Nisha |last5=Tollefson |first5=Jeff |last6=Courtland |first6=Rachel |last7=Law |first7=Yao-Hua |last8=Maher |first8=Brendan |last9=Else |first9=Holly |last10=Castelvecchi |first10=Davide |title=Nature's 10: Ten people who mattered in science in 2018 |journal=Nature |date=18 December 2018 |volume=564 |issue=7736 |pages=325–335 |doi=10.1038/d41586-018-07683-5 |pmid=30563976 |bibcode=2018Natur.564..325G |doi-access=free }}</ref><ref name=n10>{{cite journal |last1=Cyranoski |first1=David |last2=Gaind |first2=Nisha |last3=Gibney |first3=Elizabeth |last4=Masood |first4=Ehsan |last5=Maxmen |first5=Amy |last6=Reardon |first6=Sara |last7=Schiermeier |first7=Quirin |last8=Tollefson |first8=Jeff |last9=Witze |first9=Alexandra |title=Nature's 10: Ten people who mattered in science in 2019 |journal=Nature |date=17 December 2019 |volume=576 |issue=7787 |pages=361–372 |doi=10.1038/d41586-019-03749-0 |pmid=31848484 |bibcode=2019Natur.576..361C |doi-access=free }}</ref> In 2019 he won the [[Hideyo Noguchi Africa Prize]] from the Government of Japan.<ref>{{cite web|url=https://www.mofa.go.jp/af/af1/page22e_000884.html|title= Laureates of the Third Hideyo Noguchi Africa Prize |publisher=Ministry of Foreign Affairs of Japan|access-date= 2 October 2019}}</ref> Muyembe was included in [[Time 100|''Time''{{'}}s 100]] Most Influential People of 2020.<ref>{{Cite magazine|title=Jean-Jacques Muyembe Tamfum: The 100 Most Influential People of 2020|url=https://time.com/collection/100-most-influential-people-2020/5888331/jean-jacques-muyembe-tamfum/|access-date=2020-09-23|magazine=[[Time (magazine)|Time]]}}</ref> In 2022, Harvard University awarded him an honorary Doctor of Science.<ref>{{Cite web |last=gazetteterrymurphy |date=2022-05-26 |title=Harvard awards seven honorary degrees |url=https://news.harvard.edu/gazette/story/2022/05/harvard-awards-seven-honorary-degrees-2/ |access-date=2024-05-09 |website=Harvard Gazette |language=en-US}}</ref> In 2023, he is awarded 2023 WHO Director General’s Global Leaders Awards as a distinguished scientist and public health leader who was closely involved in the discovery of Ebola before advancing to leadership positions in global health. The award honours his lifetime achievements in public health. <ref>{{cite tweet|number=1660307867977564160 |user=WHO|title=The 2023 WHO Director General's Global Leaders Awards are given to Jean-Jacques Muyembe-Tamfum and Pieter Piot. Both are distinguished scientists and public health leaders who were closely involved in the discovery of Ebola before advancing to leadership positions in global health. The award honours their lifetime achievements in public health |language=en|date=2023-05-21}}</ref>


== References ==
== References ==
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[[Category:People from Bandundu Province]]
[[Category:Lovanium University people]]
[[Category:Lovanium University alumni]]
[[Category:Living people]]
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[[Category:Year of birth missing (living people)]]
[[Category:Epidemiologists]]
[[Category:Epidemiologists]]
[[Category:Ebola researchers]]
[[Category:Ebola researchers]]
[[Category:21st-century Democratic Republic of the Congo people]]

Revision as of 03:03, 7 August 2024

Jean-Jacques Muyembe
Born
Jean-Jacques Muyembe-Tamfum
Alma materUniversity of Leuven (PhD)
Lovanium University
Known forEbola discovery,[2] prevention & treatment
AwardsNature's 10 (2019)[1]
Hideyo Noguchi Africa Prize (2019)
Royal Society Africa Prize (2015)
Scientific career
InstitutionsDemocratic Republic of the Congo
National Institute for Biomedical Research
ThesisMode d'action des inducteurs d'interferon non-viraux dans une infection virale de la souris (1973)

Jean-Jacques Muyembe is a Congolese microbiologist. He is the general director of the Democratic Republic of the Congo Institut National pour la Recherche Biomedicale (INRB). He was part of team at the Yambuku Catholic Mission Hospital that investigated the first Ebola outbreak, and was part of the effort that discovered Ebola as a new disease, although his exact role is still subject to controversy.[2][3] In 2016, he led the research that designed, along with other researchers at the INRB and the National Institute of Health Vaccine Research Center in the US, one of the most promising treatment for Ebola, mAb114.[4] The treatment was successfully experimented during recent outbreaks in the DRC,[5] on the express decision of the then DRC Minister of Health, Dr Oly Ilunga, despite a prior negative advice from the World Health Organization.[6]

Early life and education

Muyembe grew up in Bandundu Province, the child of farmers. He was educated in schools run by Jesuits. He studied medicine, starting in 1962, at the Lovanium University in the Belgian Congo (Democratic Republic of the Congo) where he became interested in microbiology and graduated in 1969.[7] He earned a PhD in virology at the University of Leuven in Belgium, working on viral infections with mouse models.[7][8] He returned to Zaire (Democratic Republic of the Congo) in 1973 and worked in the cholera outbreak control.[9] In 1974 there was a cholera outbreak in Matadi, which was the first crisis that Muyembe worked on.[8]

Career

Scanning electron micrograph of the Ebola virus in an African green monkey kidney cell

Muyembe was described by The Lancet as Africa's Ebola hunter.[9] He first came across Ebola virus in 1976 at a Belgian hospital in Yambuku.[9][10] Using a long steel rod, Muyembe took liver biopsies from three nuns who had died, but the results were inconclusive. He was the first scientist to come into contact with the virus and survive.[11] Muyembe has been described as one of the discoverers of Ebola due to his work in the 1976 outbreak.[2] He took the blood of a sick nurse, which was sent for analysis at the Institute for Tropical Medicine in Antwerp, then to the Centers for Disease Control and Prevention, where Peter Piot used the sample to discover Ebola.[9] That version of events, regarding his role in the 1976 outbreak, was later refuted in a 2016 scientific article he co-signed with some of the remaining actors of that first epidemic.[3]

He was appointed dean of the University of Kinshasa Medical School in 1978.[8] In 1981 Muyembe joined the Institut Pasteur de Dakar in Senegal, working with the Centers for Disease Control and Prevention to study the Ebola and Marburg virus.[8] In 1998 he was made the director of the Democratic Republic of the Congo National Institute for Biomedical Research.[12]

He has acted as an adviser to the World Health Organization Emergency Committee on Ebola.[13] Here he leads 15 researchers studying sleeping sickness, bas-Congo virus and the Ebola.[13] He has advised political leadership in West Africa.[14]

He recognised the sociocultural challenges of Ebola, trying to encourage hospitals improve their infection control and community engagement.[9] He worked with David L. Heymann on the Ebola outbreak in 1995.[9] He was called by the director of the Kikwit General Hospital who was asking for help with an outbreak of deadly diarrhea. When Muyembe arrived, he recognised it was Ebola, and sent samples for confirmation at the Centers for Disease Control and Prevention.[8] He has chaired the international committees that looked to control the Ebola outbreaks in Gabon and the Democratic Republic of the Congo.[7] He leads research into the reservoirs of the Ebola virus in the DRC.[7] In 2009, he demonstrated that the Ebola outbreaks in the DRC were due to fruit bat exposure.[15] He has developed an anti-Ebola serum therapy .[16] The anti-Ebola serum therapy, using antibodies from convalescent patients, was first tried by another medical team during the 1976 outbreak in Yambuku and subsequently recommended for future outbreaks by the International Commission set up by the Government of DRC (formerly Zaïre).[17]

In 2014, he was appointed by Director General Margaret Chan to the WHO Advisory Group on the Ebola Virus Disease Response, co-chaired by Sam Zaramba and David L. Heymann.[18]

There was a further Ebola outbreak in 2018, which took time to control due to delays in reporting.[19] The Wellcome Trust and Department for International Development donated £1 million each.[19] He pioneered the use of an experimental Ebola vaccine during the outbreak to limit the spread of the virus, including vaccinating health professionals.[20][21] That position on the use of experimental drugs during outbreaks stirred some heated debate in the DRC, with Dr Oly Ilunga eventually resigning from his position as the Minister of Health, citing undue pressure and interference from unnamed multinational pharmaceutical firms.[22]

Muyembe has established multiple research facilities, including a polio and influenza lab. In 2017 he partnered with the Japan International Cooperation Agency to build a research complex with several biosafety labs.[7] As of 2018, the DRC still have none of their own labs to test for Ebola.[7]

On April 3, 2020, during a press conference in Kinshasa, Muyembe advocated for the trial in DRC of experimental vaccines against the COVID-19 virus in the midst of a major pandemic, generating a serious backlash from the congolese population.[23] He eventually backtracked, claiming a misunderstanding.[24]

Awards and honours

In 2015, he was awarded the Christophe Mérieux Prize to study further research in the Congo Basin.[9][25] That year he was awarded the Royal Society Africa Prize "for his seminal work on viral haemorrhagic fevers, including Ebola, generating the foundation of our understanding of the epidemiology, clinical manifestations and control of outbreaks of these viral infections".[12][26][27][28] He was presented with the Lifetime Achievement Award at the 2015 International Symposium on Filoviruses. He was named as one of Nature's 10 in 2018 and 2019.[29][1] In 2019 he won the Hideyo Noguchi Africa Prize from the Government of Japan.[30] Muyembe was included in Time's 100 Most Influential People of 2020.[31] In 2022, Harvard University awarded him an honorary Doctor of Science.[32] In 2023, he is awarded 2023 WHO Director General’s Global Leaders Awards as a distinguished scientist and public health leader who was closely involved in the discovery of Ebola before advancing to leadership positions in global health. The award honours his lifetime achievements in public health. [33]

References

  1. ^ a b Cyranoski, David; Gaind, Nisha; Gibney, Elizabeth; Masood, Ehsan; Maxmen, Amy; Reardon, Sara; Schiermeier, Quirin; Tollefson, Jeff; Witze, Alexandra (17 December 2019). "Nature's 10: Ten people who mattered in science in 2019". Nature. 576 (7787): 361–372. Bibcode:2019Natur.576..361C. doi:10.1038/d41586-019-03749-0. PMID 31848484.
  2. ^ a b c "This Congolese Doctor Discovered Ebola But Never Got Credit For It — Until Now". NPR.org. Retrieved 2019-11-05.
  3. ^ a b Breman, Joel G.; Heymann, David L.; Lloyd, Graham; McCormick, Joseph B.; Miatudila, Malonga; Murphy, Frederick A.; Muyembé-Tamfun, Jean-Jacques; Piot, Peter; Ruppol, Jean-François; Sureau, Pierre; van der Groen, Guido; Johnson, Karl M. (15 October 2016). "Discovery and Description of Ebola Zaire Virus in 1976 and Relevance to the West African Epidemic During 2013–2016". Journal of Infectious Diseases. 214 (suppl 3): S93–S101. doi:10.1093/infdis/jiw207. PMC 5050466. PMID 27357339.
  4. ^ Corti D, Misasi J, Mulangu S, Stanley DA, Kanekiyo M, Wollen S, et al. (March 2016). "Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody". Science. 351 (6279): 1339–42. Bibcode:2016Sci...351.1339C. doi:10.1126/science.aad5224. PMID 26917593.
  5. ^ "For the first time, clinical trial data show Ebola drugs improve survival rates". STAT. 12 August 2019.
  6. ^ "Ebola outbreak opens way to chaotic jockeying to test experimental drugs". STAT. 30 May 2018.
  7. ^ a b c d e f "Jean-Jacques Muyembe". WHO. Archived from the original on July 17, 2015. Retrieved 2018-12-21.
  8. ^ a b c d e "Jean-Jacques Muyembe Tamfum: a life's work on Ebola". Bulletin of the World Health Organization. 96 (12): 804–805. 1 December 2018. doi:10.2471/BLT.18.031218. PMC 6249701. PMID 30505027.
  9. ^ a b c d e f g Honigsbaum, Mark (June 2015). "Jean-Jacques Muyembe-Tamfum: Africa's veteran Ebola hunter". The Lancet. 385 (9986): 2455. doi:10.1016/S0140-6736(15)61128-X. PMID 26122060. S2CID 25547601.
  10. ^ Rosello, Alicia; Mossoko, Mathias; Flasche, Stefan; Van Hoek, Albert Jan; Mbala, Placide; Camacho, Anton; Funk, Sebastian; Kucharski, Adam; Ilunga, Benoit Kebela; Edmunds, W John; Piot, Peter; Baguelin, Marc; Muyembe Tamfum, Jean-Jacques (2015). "Ebola virus disease in Zaire (the Democratic Republic of the Congo), 1976-2014". eLife. 4. doi:10.7554/eLife.09015. PMC 4629279. PMID 26525597.
  11. ^ McNeish, Hannah (2017-03-24). "He Treated The Very First Ebola Cases 40 Years Ago. Then He Watched The World Forget". Huffington Post. Retrieved 2018-12-21.
  12. ^ a b "Jean-Jacques Muyembe-Tamfum, MD, PhD « ICREID". Archived from the original on 2018-12-22. Retrieved 2018-12-21.
  13. ^ a b "Professor Jean-Jacques Muyembe-Tamfum | Royal Society". royalsociety.org. Retrieved 2018-12-21.
  14. ^ Stokes, Elaisha (2014-10-24). "How the Democratic Republic of Congo Fought A Different Ebola Outbreak". Vice News. Retrieved 2018-12-21.
  15. ^ Leroy, Eric M.; Epelboin, Alain; Mondonge, Vital; Pourrut, Xavier; Gonzalez, Jean-Paul; Muyembe-Tamfum, Jean-Jacques; Formenty, Pierre (2009). "Human Ebola Outbreak Resulting from Direct Exposure to Fruit Bats in Luebo, Democratic Republic of Congo, 2007". Vector-Borne and Zoonotic Diseases. 9 (6): 723–728. doi:10.1089/vbz.2008.0167. PMID 19323614.
  16. ^ "Jean-Jacques Muyembe receives the Christophe Merieux prize - gdri-ehede". gdri-ehede.univ-fcomte.fr. Retrieved 2018-12-21.
  17. ^ Report of an International Commission (1978). "Ebola haemorrhagic fever in Zaire, 1976". Bulletin of the World Health Organization. 56 (2): 271–293. PMC 2395567. PMID 307456.
  18. ^ Members of the WHO Advisory Group on the Ebola Virus Disease Response World Health Organization.
  19. ^ a b Yong, Ed (2018-05-11). "The New Ebola Outbreak Could Take 'Three, Maybe Four' Months to Control". The Atlantic. Retrieved 2018-12-21.
  20. ^ "Ebola resurgit car nous ne connaissons pas son réservoir". BBC News Afrique. 2018-05-18. Retrieved 2018-12-21.
  21. ^ Robert, Alexis; Camacho, Anton; Edmunds, W John; Baguelin, Marc; Muyembe Tamfum, Jean-Jacques; Rosello, Alicia; Keita, Sakoba; Eggo, Rosalind M. (2018), Effect of vaccinating health care workers to control Ebola virus disease: A modelling analysis of outbreak data (PDF), doi:10.1101/113506
  22. ^ Un an d’Ebola en RDC: qui croire dans la polémique sur le deuxième vaccin? http://www.rfi.fr/fr/afrique/20190802-ebola-rdc-croire-polemique-deuxieme-vaccin
  23. ^ DR Congo 'prepared' to take part in vaccine testing: official. by AFP |https://news.yahoo.com/dr-congo-prepared-part-vaccine-testing-official-215705424.html
  24. ^ "Covid-19 et vaccin en RDC: les précisions Dr Muyembe". YouTube.
  25. ^ Institut de France, Jean-Jacques Muyembe Tamfum, lauréat du Prix Christophe Mérieux 2015., retrieved 2018-12-21
  26. ^ "Ghanaian scientist wins 2015 Royal Society Pfizer Early Career Award". citifmonline.com. 2015-08-20. Retrieved 2018-12-21.
  27. ^ The Royal Society Pfizer Award. The Royal Society.
  28. ^ "Royal Society Pfizer Awards, 19th October 2015 | Alsford Lab". blogs.lshtm.ac.uk. 23 November 2015. Retrieved 2018-12-21.
  29. ^ Gibney, Elizabeth; Callaway, Ewen; Cyranoski, David; Gaind, Nisha; Tollefson, Jeff; Courtland, Rachel; Law, Yao-Hua; Maher, Brendan; Else, Holly; Castelvecchi, Davide (18 December 2018). "Nature's 10: Ten people who mattered in science in 2018". Nature. 564 (7736): 325–335. Bibcode:2018Natur.564..325G. doi:10.1038/d41586-018-07683-5. PMID 30563976.
  30. ^ "Laureates of the Third Hideyo Noguchi Africa Prize". Ministry of Foreign Affairs of Japan. Retrieved 2 October 2019.
  31. ^ "Jean-Jacques Muyembe Tamfum: The 100 Most Influential People of 2020". Time. Retrieved 2020-09-23.
  32. ^ gazetteterrymurphy (2022-05-26). "Harvard awards seven honorary degrees". Harvard Gazette. Retrieved 2024-05-09.
  33. ^ @WHO (2023-05-21). "The 2023 WHO Director General's Global Leaders Awards are given to Jean-Jacques Muyembe-Tamfum and Pieter Piot. Both are distinguished scientists and public health leaders who were closely involved in the discovery of Ebola before advancing to leadership positions in global health. The award honours their lifetime achievements in public health" (Tweet) – via Twitter.
Scholia has a profile for Jean-Jacques Muyembe-Tamfum (Q32678288).
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