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In 1967, Seeman became an assistant professor in the Department of Pharmacology at the [[University of Toronto]]. In 1970, he was appointed a professor.
In 1967, Seeman became an assistant professor in the Department of Pharmacology at the [[University of Toronto]]. In 1970, he was appointed a professor.


In 1974, having spent years in search for the binding site of antipsychotic medication, he discovered the [[Dopamine receptor|dopamine D2 receptor]], the basis for the [[dopamine hypothesis of schizophrenia]].<ref>{{Cite journal| author = P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong| title = Brain receptors for antipsychotic drugs and dopamine: direct binding assays| journal = [[Proceedings of the National Academy of Sciences of the United States of America]]| volume = 72| issue = 11| pages = 4376–4370|date=November 1975| pmid = 1060115| pmc = 388724| doi = 10.1073/pnas.72.11.4376| bibcode = 1975PNAS...72.4376S}}</ref><ref>{{cite journal|title=People|journal=CMAJ|year=1994|volume=151|number=8|pages= 1186–1187|pmc=1337253}}</ref>
In 1974, having spent years in search of the binding site of antipsychotic medication, he discovered the [[Dopamine receptor|dopamine D2 receptor]], the basis for the [[dopamine hypothesis of schizophrenia]].<ref>{{Cite journal| author = P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong| title = Brain receptors for antipsychotic drugs and dopamine: direct binding assays| journal = [[Proceedings of the National Academy of Sciences of the United States of America]]| volume = 72| issue = 11| pages = 4376–4370|date=November 1975| pmid = 1060115| pmc = 388724| doi = 10.1073/pnas.72.11.4376| bibcode = 1975PNAS...72.4376S}}</ref><ref>{{cite journal|title=People|journal=CMAJ|year=1994|volume=151|number=8|pages= 1186–1187|pmc=1337253}}</ref>


In 2001, he was made an Officer of the [[Order of Canada]] "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".<ref>{{OCC|4875}}</ref>
In 2001, he was made an Officer of the [[Order of Canada]] "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".<ref>{{OCC|4875}}</ref>
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In 1985, he was made a Fellow of the [[Royal Society of Canada]].<ref>http://www.sciandmed.com/sm/journalviewer.aspx?issue=1066&article=787&action=1</ref>
In 1985, he was made a Fellow of the [[Royal Society of Canada]].<ref>http://www.sciandmed.com/sm/journalviewer.aspx?issue=1066&article=787&action=1</ref>


He is married to Dr. [[Mary V. Seeman]].<ref>{{cite news |title=Most Wikipedia profiles are about men – these women in Australia are hoping to change that |url=https://www.sbs.com.au/news/most-wikipedia-profiles-are-about-men-these-women-in-australia-are-hoping-to-change-that |access-date=27 July 2019 |work=SBS News |language=en}}</ref>
He was married to Dr. [[Mary V. Seeman]].<ref>{{cite news |title=Most Wikipedia profiles are about men – these women in Australia are hoping to change that |url=https://www.sbs.com.au/news/most-wikipedia-profiles-are-about-men-these-women-in-australia-are-hoping-to-change-that |access-date=27 July 2019 |work=SBS News |language=en}}</ref>


== Notes ==
== Notes ==

Revision as of 09:14, 20 January 2021

Philip Seeman
Born(1934-02-08)8 February 1934
Winnipeg, Manitoba
Died9 January 2021(2021-01-09) (aged 86)
AwardsOrder of Canada

Philip Seeman, OC FRSC (February 8, 1934 - 9 January 2021) was a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.[1]

Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He received a Bachelor of Science degree, honours physics & physiology (1955), a Master of Science degree, physiology of transport & secretion (1956), and a Doctor of Medicine (1960) from McGill University. In 1966, he received a Ph.D. in life sciences from Rockefeller University.

In 1967, Seeman became an assistant professor in the Department of Pharmacology at the University of Toronto. In 1970, he was appointed a professor.

In 1974, having spent years in search of the binding site of antipsychotic medication, he discovered the dopamine D2 receptor, the basis for the dopamine hypothesis of schizophrenia.[2][3]

In 2001, he was made an Officer of the Order of Canada "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".[4]

In 1985, he was made a Fellow of the Royal Society of Canada.[5]

He was married to Dr. Mary V. Seeman.[6]

Notes

  1. ^ "Philip SEEMAN". The Globe and Mail. Retrieved 19 January 2021.
  2. ^ P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong (November 1975). "Brain receptors for antipsychotic drugs and dopamine: direct binding assays". Proceedings of the National Academy of Sciences of the United States of America. 72 (11): 4376–4370. Bibcode:1975PNAS...72.4376S. doi:10.1073/pnas.72.11.4376. PMC 388724. PMID 1060115.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ "People". CMAJ. 151 (8): 1186–1187. 1994. PMC 1337253.
  4. ^ Order of Canada citation
  5. ^ http://www.sciandmed.com/sm/journalviewer.aspx?issue=1066&article=787&action=1
  6. ^ "Most Wikipedia profiles are about men – these women in Australia are hoping to change that". SBS News. Retrieved 27 July 2019.

References

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