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In 1974, having spent years in search for the binding site of antipsychotic medication, he discovered the [[Dopamine receptor|dopamine D2 receptor]], the basis for the [[dopamine hypothesis of schizophrenia]].<ref>{{Cite journal| author = P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong| title = Brain receptors for antipsychotic drugs and dopamine: direct binding assays| journal = [[Proceedings of the National Academy of Sciences of the United States of America]]| volume = 72| issue = 11| pages = 4376–4370|date=November 1975| pmid = 1060115| pmc = 388724| doi = 10.1073/pnas.72.11.4376}}</ref><ref>{{cite journal|title=People|journal=CMAJ|year=1994|volume=151|number=8|pages= 1186–1187|pmc=1337253}}</ref>
In 1974, having spent years in search for the binding site of antipsychotic medication, he discovered the [[Dopamine receptor|dopamine D2 receptor]], the basis for the [[dopamine hypothesis of schizophrenia]].<ref>{{Cite journal| author = P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong| title = Brain receptors for antipsychotic drugs and dopamine: direct binding assays| journal = [[Proceedings of the National Academy of Sciences of the United States of America]]| volume = 72| issue = 11| pages = 4376–4370|date=November 1975| pmid = 1060115| pmc = 388724| doi = 10.1073/pnas.72.11.4376}}</ref><ref>{{cite journal|title=People|journal=CMAJ|year=1994|volume=151|number=8|pages= 1186–1187|pmc=1337253}}</ref>


In 2001, he was made an Officer of the [[Order of Canada]] "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".<ref>{{OCC|4875}}</ref>
In 2001, he was made an Officer of the [[Order of Canada]] "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".<ref>{{OCC|4875}}</ref>


In 1985, he was made a Fellow of the [[Royal Society of Canada]].<ref>http://www.sciandmed.com/sm/journalviewer.aspx?issue=1066&article=787&action=1</ref>
In 1985, he was made a Fellow of the [[Royal Society of Canada]].<ref>http://www.sciandmed.com/sm/journalviewer.aspx?issue=1066&article=787&action=1</ref>
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* [http://www.medscape.com/viewarticle/547112 Probing the Biology of Psychosis, Schizophrenia, and Antipsychotics: An Expert Interview With Dr. Philip Seeman, MD, PhD] - an interview on the [[Medscape]] website
* [http://www.medscape.com/viewarticle/547112 Probing the Biology of Psychosis, Schizophrenia, and Antipsychotics: An Expert Interview With Dr. Philip Seeman, MD, PhD] - an interview on the [[Medscape]] website
* [http://www.esi-topics.com/schizophrenia/interviews/dr-philip-seeman.html Schizophrenia] - an essay by Philip Seeman, November 2001
* [http://www.esi-topics.com/schizophrenia/interviews/dr-philip-seeman.html Schizophrenia] - an essay by Philip Seeman, November 2001

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{{DEFAULTSORT:Seeman, Philip}}
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Revision as of 04:04, 14 September 2018

Philip Seeman
Born (1934-02-08) February 8, 1934 (age 90)
Winnipeg, Manitoba
AwardsOrder of Canada

Philip Seeman, OC FRSC (born February 8, 1934) is a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.

Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He received a Bachelor of Science degree, honours Physics & Physiology (1955), a Master of Science degree, Physiology of Transport & Secretion (1956), and a Doctor of Medicine (1960) from McGill University. In 1966, he received a Ph.D. in Life Sciences from Rockefeller University.

In 1967, Seeman became an Assistant Professor in the Department of Pharmacology at the University of Toronto. In 1970, he was appointed a Professor.

In 1974, having spent years in search for the binding site of antipsychotic medication, he discovered the dopamine D2 receptor, the basis for the dopamine hypothesis of schizophrenia.[1][2]

In 2001, he was made an Officer of the Order of Canada "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".[3]

In 1985, he was made a Fellow of the Royal Society of Canada.[4]

Notes

  1. ^ P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong (November 1975). "Brain receptors for antipsychotic drugs and dopamine: direct binding assays". Proceedings of the National Academy of Sciences of the United States of America. 72 (11): 4376–4370. doi:10.1073/pnas.72.11.4376. PMC 388724. PMID 1060115.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ "People". CMAJ. 151 (8): 1186–1187. 1994. PMC 1337253.
  3. ^ Order of Canada citation
  4. ^ http://www.sciandmed.com/sm/journalviewer.aspx?issue=1066&article=787&action=1

References

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