Talk:Tyramine

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Cleanup

Hi, I have had a go at cleaning up tyramine but appart from a lack of references (in particular in the last paragraph - we need to track down the "recent review article") I cannot see very much wrong with it. Could you give me more information on what you think is wrong with the article? Cheers, Andreww 09:58, 30 October 2005 (UTC)[reply]

The main thing is, it's really two independent chunks of text, with little to connect them. The second and third paragraphs say pretty much the same thing in two different ways, and the only section that covers restricted tyramine diets (only in passing) is the fourth, which is a solid wall of text poorly formatted for online reading.

I'm also really curious about where the material from [1] and [2] came from. My suspicion is that we technically shouldn't be using the last two paragraphs at all, and ought to rewrite them entirely. ‣ᓛᖁ

ᑐ 12:09, 30 October 2005 (UTC)[reply]

Citing a study that shows the absence of an effect should also give some indication of the power of that study, such as the number of participants. It's possible for a small but sound study to not detect a small effect. --122.107.243.206 (talk) 06:24, 30 April 2009 (UTC)[reply]

Octopamine

I suspect that tyramine is not "degraded to octopamine" look at the structures; I think that the second paragraph should be cut out. —Preceding unsigned comment added by Threelegduck (talk • contribs) 02:31, 11 May 2008 (UTC)[reply]

Octopamine is degraded from tyramine, however the article states that octopamine does not activate alpha or beta adrenergic receptors, which is untrue. — Preceding unsigned comment added by 82.36.155.243 (talk) 02:26, 8 April 2012 (UTC)[reply]

Trivia

In Silence of the Lambs, at one point Hannibal Lecter talks about eating the liver of a census-taker, along with "some fava beans and a nice Chianti". I stumbled across this article and found it interesting that all three of these foods are listed as containing tyramine. Is there a deeper meaning in this? Was the author including a little in-joke for psychiatrists? My post is probably a waste of time, but I just thought I'd share this with y'all in the hope that someone else finds this as interesting as I did. AllGloryToTheHypnotoad (talk) 16:49, 31 July 2008 (UTC)[reply]

I was wondering the same thing myself. The author might very well have done so; he includes quite a few obscure references -- the following site catalogs some of them:

http://silence.hannotations.com/ Afalbrig (talk) 13:09, 7 December 2008 (UTC)[reply]

Acting so, Hannibal Lecter demonstrates he's off his medication, because he doesn't get a cheese effect taking in all this tyramine. — Preceding unsigned comment added by 84.119.66.183 (talk) 13:00, 7 May 2012 (UTC)[reply]

Merge from foods containing tyramine

Given that this article already has a brief "occurrence" section that lists foods containing tyramine, I think we can condense the multi-section format of foods containing tyramine and bring it into this article. --McGeddon (talk) 11:47, 17 April 2009 (UTC)[reply]

I support the merge, no need for a separate article Maen. K. A. (talk) 16:40, 20 April 2009 (UTC)[reply]

I prefer keeping them separate. Some people (including me) just want a list. 220.233.208.223 (talk) 08:20, 23 May 2009 (UTC)[reply]

support the merge--7amada'sback:) (talk) 19:00, 30 May 2009 (UTC)[reply]

No merge'. A chemical compound and foods containing this compound are different subjects.Biophys (talk) 13:56, 12 July 2009 (UTC)[reply]

No merge - both articles are useful separately and would be too large as one. 25 Feb 2010 —Preceding unsigned comment added by 72.196.120.74 (talk) 03:33, 26 February 2010 (UTC)[reply]

No merge'. I would never have found the topic against food if the subject had been merged under Tyramine. —Preceding unsigned comment added by J'ai osé (talk • contribs) 10:46, 14 October 2010 (UTC)[reply]

Synephrine

Synephrine is a drug, it's not a naturally occuring neurotransmitter. — Preceding unsigned comment added by 80.33.90.100 (talk) 18:16, 29 March 2012 (UTC)[reply]

If you want to be taken seriously, you are advised to back up your claims substantially.

As for the subject matter of the comment: Synephrine is a part of the biosynthetic pathway of the cathecolamines. It is clearly a naturally occuring compound.

I will remove the dubious tag from the relevant section of the article. Please comment here if this is opposed to.

Thank you.

Spectralyst (talk) 03:08, 5 May 2014 (UTC)[reply]

Physical effects and pharmacology section

Firstly, thanks to Jytdog for cleaning up garbage from this section. However, the section is still a mess and would benefit from being taken care of. I have made an effort to restructure and source some of the material contained, but have left the paragraphs on medical effects to be evaluated by someone better qualified.

Additionally, I reinserted parts of the paragraph on migraine interaction as it is seemingly adequately sourced. Please state your case before removing this section again.

Further, I would like to propose a split of the section into two seperate sections Pharmacology and Physical/Biological/Medical effects, and expand on the Pharmacology section to include more in depth information on pharmacodynamics and pharmacokinetics. However, time restrains currently prevents this from being done by this user.

Thank you and good night.

Spectralyst (talk) 19:54, 6 May 2014 (UTC)[reply]

Questionable section on foods containing tyramine

There are no citations for the foods containing tyramine section and there are numerous modern studies that contradict the information in this article, showing that very few foods contain a significant level of tyramine and that people taking maoi's can eat foods like chocolate, pepperoni, many cheeses and drink alcohol without issue.

I myself am on 90mg Phenelzine and I have no pressor response to large amounts of alcohol, pizzas with the meat toppings mentioned in this article, chocolate, and cheeses like cheddar, if the information in this article was true I would have died from a hypertensive crisis. — Preceding unsigned comment added by 151.225.64.61 (talk) 02:09, 11 November 2014 (UTC)[reply]

I noticed an ambiguity which I think is potentially misleading, also in the 'Occurrence' section: it states tyramine is found in alcoholic drinks, but according to other websites I've checked, it is absent from distilled alcoholic drinks such as vodka. I'm afraid the best source I could cite for that is WebMD - I'm not sure whether that's considered a strong source to cite? Also I was wondering about the above comments about chocolate etc (unfortunately the edit was from an unsigned IP, but still, it's a pity nobody has addressed these directly...?). PaulineDataWard (talk) 18:33, 14 October 2018 (UTC)[reply]

Broken link

The link for reference 17 "Tyramine-restricted Diet 1998, W.B. Saunders Company." is producing a '404 page not found' error. — Preceding unsigned comment added by PaulineDataWard (talk • contribs) 18:27, 14 October 2018 (UTC)[reply]