(Q27824826)

13 November 2016

title

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic (English)

1 reference

Proceedings of the National Academy of Sciences of the United States of America

PubMed publication ID

13 November 2016

Peter K Vogt

3

0 references

author name string

Sohye Kang

series ordinal

1

0 references

Andreas G Bader

series ordinal

2

0 references

language of work or name

English

0 references

publication date

18 January 2005

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published in

0 references

volume

102

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issue

3

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page(s)

802-7

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cites work

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

20 March 2017

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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7 April 2017

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Effects of ZD1839 (Iressa, gefitinib) treatment on symptoms and quality of life in patients with advanced non-small cell lung cancer

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29 September 2017

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An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

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Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

29 September 2017

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29 September 2017

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Identification of PTEN mutations in metastatic melanoma specimens

29 September 2017

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Ribosomal S6 kinase signaling and the control of translation

29 September 2017

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p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis

29 September 2017

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

29 September 2017

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Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

29 September 2017

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Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate

29 September 2017

1 reference

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The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicity

29 September 2017

1 reference

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The mRNA 5' cap-binding protein eIF4E and control of cell growth

2 June 2018

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Characteristics of two new avian tumor virus subgroups

2 June 2018

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Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545580

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545580

PIK3CA is implicated as an oncogene in ovarian cancer.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408864102

Mutations of PIK3CA in Anaplastic Oligodendrogliomas, High-Grade Astrocytomas, and Medulloblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408864102

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408864102

AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408864102

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408864102

The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545580

AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545580

Somatic mutations of PTEN in glioblastoma multiforme

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545580

Expression of PTEN and PTEN pseudogene in endometrial carcinoma

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15647370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression and overactivation of Akt in thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15647370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/15647370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0408864102

1 reference

ADS bibcode

2005PNAS..102..802K

0 references

1 reference

1 reference

PubMed publication ID

15647370

1 reference