Извор странице 5-MeO-NBpBrT

{{Drugbox-lat
| verifiedrevid = 477345825
| IUPAC_name = -{N}--(4-Bromobenzil)-2-(5-metoksi-1-{H}--indol-3-il)etanamin
| image = 5-MeO-NBpBrT_structure.png
| width =
| image2 =
| width2 =

<!--Clinical data-->
| tradename = 
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B            / C / D / X -->
| pregnancy_category = 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status = 
| routes_of_administration =

<!--Pharmacokinetic data-->
| bioavailability = 
| protein_bound = 
| metabolism = 
| elimination_half-life = 
| excretion =

<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|}}
| CAS_number = 
| ATC_prefix = none
| ATC_suffix = 
| ATC_supplemental = 
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 57427
| DrugBank_Ref =
| DrugBank =
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C18H19BrN2O/c1-22-16-6-7-18-17(10-16)14(12-21-18)8-9-20-11-13-2-4-15(19)5-3-13/h2-7,10,12,20-21H,8-9,11H2,1H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = XHLOUFPZLUULGI-UHFFFAOYSA-N
| PubChem = 5124753
| IUPHAR_ligand =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4299315

<!--Chemical data-->
| chemical_formula = 
| C=18 | H=19 | Br=1 | N=2 | O=1  
| molecular_weight = 359,260 -{g/mol}-
| smiles = c3cc(Br)ccc3CNCCc(cnc1cc2)c1cc2OC
}}

-{'''5-MeO-NBpBrT'''}- (''5-Metoksi--{N}--(4-bromobenzil)triptamin'') je lek koji deluje kao [[antagonist (farmakologija)|antagonist]] za [[5-HT2A receptor|-{5-HT<sub>2A</sub>}-]] [[Receptor (biohemija)|receptor]],<ref>-{[http://www.catbull.com/alamut/Bibliothek/NielsJensen-Aeruginascin.pdf Niels Jensen. Tryptamines as Ligands and Modulators of the Serotonin 5-HT2A Receptor and the Isolation of Aeruginascin from the Hallucinogenic Mushroom Inocybe aeruginascens. PhD dissertation, Georg-August-Universität zu Göttingen, 2004.]}-</ref> koji je sto puta selektivniji za taj receptor u odnosu na blisko srodni [[5-HT2C receptor|-{5-HT<sub>2C</sub>}-]] receptor.<ref>-{Glennon RA, Dukat M, el-Bermawy M, Law H, De los Angeles J, Teitler M, King A, Herrick-Davis K. Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines. ''Journal of Medicinal Chemistry''. 1994 Jun 24;37(13):1929-35. {{PMID|8027974}}}-</ref><ref>-{[http://epub.uni-regensburg.de/12119/ Maria Silva PhD. Theoretical study of the interaction of agonists with the 5-HT2A receptor. Universität Regensburg, 2009.]}-</ref><ref name="pmid21088982">{{cite journal |vauthors=Silva ME, Heim R, Strasser A, Elz S, Dove S |title=Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor |journal=Journal of Computer-aided Molecular Design |volume=25 |issue=1 |year=2011 |pmid=21088982 |doi=10.1007/s10822-010-9400-2 |url=| pages = 51–66 }}</ref>

== Reference ==
{{reflist}}

== Vidi još ==
* -{[[25B-NBOMe]]}-
* -{[[25I-NBF]]}-
* -{[[RH-34]]}-
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{{Serotonergici-lat}}

{{normativna kontrola}}

[[Категорија:5-ХТ2 антагонисти]]
[[Категорија:Триптамини]]
[[Категорија:Органобромиди]]
[[Категорија:Фенолни етри]]