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Pancreatic pseudocyst

MedGen UID:
18280
•Concept ID:
C0030299
•
Disease or Syndrome
Synonyms: Pancreatic Pseudocyst; Pancreatic Pseudocysts; Pseudocyst, Pancreatic; Pseudocysts, Pancreatic
SNOMED CT: Pancreatic pseudocyst (111374002); Pseudocyst of pancreas (111374002)
 
HPO: HP:0005206

Definition

Cyst-like space not lined by epithelium and contained within the pancreas. Pancreatic pseudocysts are often associated with pancreatitis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic pseudocyst

Conditions with this feature

Hereditary pancreatitis
MedGen UID:
116056
•Concept ID:
C0238339
•
Disease or Syndrome
PRSS1-related hereditary pancreatitis (HP) is characterized by episodes of acute pancreatitis (AP) and recurrent acute pancreatitis (RAP: >1 episode of AP), with frequent progression to chronic pancreatitis (CP). Manifestations of acute pancreatitis can range from vague abdominal pain lasting one to three days to severe abdominal pain lasting days to weeks and requiring hospitalization.
See: Condition Record
Hereditary pancreatitis

Professional guidelines

PubMed

Endoscopic treatment of chronic pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Updated August 2018.
Dumonceau JM, Delhaye M, Tringali A, Arvanitakis M, Sanchez-Yague A, Vaysse T, Aithal GP, Anderloni A, Bruno M, Cantú P, Devière J, Domínguez-Muñoz JE, Lekkerkerker S, Poley JW, Ramchandani M, Reddy N, van Hooft JE
Endoscopy 2019 Feb;51(2):179-193. Epub 2019 Jan 17 doi: 10.1055/a-0822-0832. PMID: 30654394
Management of pancreatitis and pancreatic: fluid collections.
Kahaleh M
Rev Gastroenterol Peru 2018 Apr-Jun;38(2):169-182. PMID: 30118464
Modern Management of Pancreatic Fluid Collections.
Andalib I, Dawod E, Kahaleh M
J Clin Gastroenterol 2018 Feb;52(2):97-104. doi: 10.1097/MCG.0000000000000940. PMID: 29095421

Recent clinical studies

Etiology

Surgical cystogastrostomy: Is it still worthwhile?
Au KP, Chok KSH
World J Gastroenterol 2024 May 7;30(17):2298-2301. doi: 10.3748/wjg.v30.i17.2298. PMID: 38813046Free PMC Article
Acute Pancreatitis and Fluid-Filled Collections: Etiology and Endoscopic Management.
Lancaster A, Zwijacz M
Gastroenterol Nurs 2019 Sep/Oct;42(5):417-419. doi: 10.1097/SGA.0000000000000396. PMID: 31574068
Therapeutical Aspects Regarding Pancreatic Pseudocysts.
David OI, Grigorean VT
Chirurgia (Bucur) 2018 May-Jun;113(3):353-362. doi: 10.21614/chirurgia.113.3.353. PMID: 29981666
Endoscopic Ultrasound-Guided Drainage of Pancreatic Fluid Collections.
Giovannini M
Gastrointest Endosc Clin N Am 2018 Apr;28(2):157-169. doi: 10.1016/j.giec.2017.11.004. PMID: 29519329
Chronic Pancreatitis.
Stram M, Liu S, Singhi AD
Surg Pathol Clin 2016 Dec;9(4):643-659. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.008. PMID: 27926364

Diagnosis

Therapeutical Aspects Regarding Pancreatic Pseudocysts.
David OI, Grigorean VT
Chirurgia (Bucur) 2018 May-Jun;113(3):353-362. doi: 10.21614/chirurgia.113.3.353. PMID: 29981666
Fluid Collections and Pseudocysts as a Complication of Acute Pancreatitis.
Braha J, Tenner S
Gastrointest Endosc Clin N Am 2018 Apr;28(2):123-130. Epub 2018 Feb 1 doi: 10.1016/j.giec.2017.11.001. PMID: 29519326
Life-threatening wirsungorrhagia.
Saouli AC, Monga-Pelami G, Addeo P, Breysacher G, Keller P, Denis B, Meyer C
Surgery 2014 Feb;155(2):353-4. Epub 2012 Dec 24 doi: 10.1016/j.surg.2012.09.018. PMID: 23270970
Diagnosis and management of pancreatic pseudocysts: what is the evidence?
Cannon JW, Callery MP, Vollmer CM Jr
J Am Coll Surg 2009 Sep;209(3):385-93. Epub 2009 Jun 18 doi: 10.1016/j.jamcollsurg.2009.04.017. PMID: 19717045
Pancreatic pseudocyst.
Habashi S, Draganov PV
World J Gastroenterol 2009 Jan 7;15(1):38-47. doi: 10.3748/wjg.15.38. PMID: 19115466Free PMC Article

Therapy

Surgical cystogastrostomy: Is it still worthwhile?
Au KP, Chok KSH
World J Gastroenterol 2024 May 7;30(17):2298-2301. doi: 10.3748/wjg.v30.i17.2298. PMID: 38813046Free PMC Article
Therapeutical Aspects Regarding Pancreatic Pseudocysts.
David OI, Grigorean VT
Chirurgia (Bucur) 2018 May-Jun;113(3):353-362. doi: 10.21614/chirurgia.113.3.353. PMID: 29981666
Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection.
Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T
Antimicrob Agents Chemother 2017 Oct;61(10) Epub 2017 Sep 22 doi: 10.1128/AAC.00954-17. PMID: 28807909Free PMC Article
Imaging acute pancreatitis.
Koo BC, Chinogureyi A, Shaw AS
Br J Radiol 2010 Feb;83(986):104-12. doi: 10.1259/bjr/13359269. PMID: 20139261Free PMC Article
Acute pancreatitis.
Geokas MC, Baltaxe HA, Banks PA, Silva J Jr, Frey CF
Ann Intern Med 1985 Jul;103(1):86-100. doi: 10.7326/0003-4819-103-1-86. PMID: 3890660

Prognosis

Management of pancreatic collections: an update.
García García de Paredes A, López-Durán S, Foruny Olcina JR, Albillos A, Vázquez-Sequeiros E
Rev Esp Enferm Dig 2020 Jun;112(6):483-490. doi: 10.17235/reed.2020.6814/2019. PMID: 32450706
Walled-off pancreatic necrosis.
Stamatakos M, Stefanaki C, Kontzoglou K, Stergiopoulos S, Giannopoulos G, Safioleas M
World J Gastroenterol 2010 Apr 14;16(14):1707-12. doi: 10.3748/wjg.v16.i14.1707. PMID: 20380001Free PMC Article
Pancreatic pseudocyst.
Habashi S, Draganov PV
World J Gastroenterol 2009 Jan 7;15(1):38-47. doi: 10.3748/wjg.15.38. PMID: 19115466Free PMC Article
Postburn pancreatitis.
Ryan CM, Sheridan RL, Schoenfeld DA, Warshaw AL, Tompkins RG
Ann Surg 1995 Aug;222(2):163-70. doi: 10.1097/00000658-199508000-00008. PMID: 7543741Free PMC Article
Acute pancreatitis.
Geokas MC, Baltaxe HA, Banks PA, Silva J Jr, Frey CF
Ann Intern Med 1985 Jul;103(1):86-100. doi: 10.7326/0003-4819-103-1-86. PMID: 3890660

Clinical prediction guides

Endoscopic treatment of chronic pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Updated August 2018.
Dumonceau JM, Delhaye M, Tringali A, Arvanitakis M, Sanchez-Yague A, Vaysse T, Aithal GP, Anderloni A, Bruno M, Cantú P, Devière J, Domínguez-Muñoz JE, Lekkerkerker S, Poley JW, Ramchandani M, Reddy N, van Hooft JE
Endoscopy 2019 Feb;51(2):179-193. Epub 2019 Jan 17 doi: 10.1055/a-0822-0832. PMID: 30654394
Echo-endoscopy: new therapeutic frontiers.
Cho CM, Dewitt J, Al-Haddad M
Minerva Gastroenterol Dietol 2011 Jun;57(2):139-58. PMID: 21587144
Pancreatic pseudocyst.
Habashi S, Draganov PV
World J Gastroenterol 2009 Jan 7;15(1):38-47. doi: 10.3748/wjg.15.38. PMID: 19115466Free PMC Article
Postburn pancreatitis.
Ryan CM, Sheridan RL, Schoenfeld DA, Warshaw AL, Tompkins RG
Ann Surg 1995 Aug;222(2):163-70. doi: 10.1097/00000658-199508000-00008. PMID: 7543741Free PMC Article
Acute pancreatitis.
Geokas MC, Baltaxe HA, Banks PA, Silva J Jr, Frey CF
Ann Intern Med 1985 Jul;103(1):86-100. doi: 10.7326/0003-4819-103-1-86. PMID: 3890660

Recent systematic reviews

Early (<4 weeks) versus standard (≥4 weeks) endoscopic drainage of pancreatic walled-off fluid collections: a systematic review and meta-analysis.
Ramai D, Enofe I, Deliwala SS, Mozell D, Facciorusso A, Gkolfakis P, Mohan BP, Chandan S, Previtera M, Maida M, Anderloni A, Adler DG, Ofosu A
Gastrointest Endosc 2023 Mar;97(3):415-421.e5. Epub 2022 Nov 15 doi: 10.1016/j.gie.2022.11.003. PMID: 36395824
Disconnected pancreatic duct syndrome and outcomes of endoscopic ultrasound-guided treatment of pancreatic fluid collections: Systematic review and meta-analysis.
Hamada T, Iwashita T, Saito T, Shiomi H, Takenaka M, Isayama H, Yasuda I, Nakai Y; WONDERFUL study group in Japan
Dig Endosc 2022 May;34(4):676-686. Epub 2021 Oct 15 doi: 10.1111/den.14142. PMID: 34544204
Head-to-head comparison between endoscopic ultrasound guided lumen apposing metal stent and plastic stents for the treatment of pancreatic fluid collections: A systematic review and meta-analysis.
Guzmán-Calderón E, Chacaltana A, Díaz R, Li B, Martinez-Moreno B, Aparicio JR
J Hepatobiliary Pancreat Sci 2022 Feb;29(2):198-211. Epub 2021 Jun 28 doi: 10.1002/jhbp.1008. PMID: 34107170
Percutaneous catheter drainage of pancreatic associated pathologies: A systematic review and meta-analysis.
Keshavarz P, Azrumelashvili T, Yazdanpanah F, Nejati SF, Ebrahimian Sadabad F, Tarjan A, Bazyar A, Mizandari M
Eur J Radiol 2021 Nov;144:109978. Epub 2021 Sep 28 doi: 10.1016/j.ejrad.2021.109978. PMID: 34607289
Pancreatic pseudocysts located in the liver: a systematic review of the literature.
Guesmi F, Zoghlami A, Saidi Y, Najeh N, Dziri C
Tunis Med 2009 Dec;87(12):801-4. PMID: 20209844

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