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Necrotizing vasculitis

MedGen UID:
230813
•Concept ID:
C1318520
•
Disease or Syndrome
Synonyms: Necrotizing Vasculitis; necrotizing vasculitis; systemic vasculitis
SNOMED CT: Necrotizing vasculitis (11791001)
 
HPO: HP:6000253
Monarch Initiative: MONDO:0800113

Definition

A histopathological finding characterized by inflammation of the arterial and/or capillary and/or venous blood vessels, leading to a change in the vascular wall as a whole. [from HPO]

Professional guidelines

PubMed

Treatment strategies for ANCA-associated vasculitides: from standard protocols to future horizons.
Reggiani F, Stella M, Calatroni M, Sinico RA
Expert Rev Clin Immunol 2024 Jul;20(7):765-780. Epub 2024 Mar 6 doi: 10.1080/1744666X.2024.2326628. PMID: 38445642
Infliximab for the treatment of refractory polyarteritis nodosa.
Ginsberg S, Rosner I, Slobodin G, Rozenbaum M, Kaly L, Jiries N, Boulman N, Awisat A, Hussein H, Novofastovski I, Silawy A, Rimar D
Clin Rheumatol 2019 Oct;38(10):2825-2833. Epub 2019 Apr 10 doi: 10.1007/s10067-019-04474-9. PMID: 30972576
Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment.
Comarmond C, Cacoub P
Autoimmun Rev 2014 Nov;13(11):1121-5. Epub 2014 Aug 20 doi: 10.1016/j.autrev.2014.08.017. PMID: 25149391

Recent clinical studies

Etiology

Targeted immunotherapy strategies in ANCA-associated vasculitis.
Puéchal X
Joint Bone Spine 2019 May;86(3):321-326. Epub 2018 Sep 7 doi: 10.1016/j.jbspin.2018.09.002. PMID: 30201478
Churg-Strauss syndrome.
Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M
Autoimmun Rev 2015 Apr;14(4):341-8. Epub 2014 Dec 11 doi: 10.1016/j.autrev.2014.12.004. PMID: 25500434
Churg-Strauss syndrome.
Pagnoux C, Guilpain P, Guillevin L
Curr Opin Rheumatol 2007 Jan;19(1):25-32. doi: 10.1097/BOR.0b013e3280119854. PMID: 17143092
Granulomatous vasculitis.
Marquez J, Flores D, Candia L, Espinoza LR
Curr Rheumatol Rep 2003 Apr;5(2):128-35. doi: 10.1007/s11926-003-0040-6. PMID: 12628043
Renal vasculitis.
D'Amico G, Sinico RA, Ferrario F
Nephrol Dial Transplant 1996;11 Suppl 9:69-74. doi: 10.1093/ndt/11.supp9.69. PMID: 9050038

Diagnosis

Polyarteritis Nodosa: Old Disease, New Etiologies.
Wolff L, Horisberger A, Moi L, Karampetsou MP, Comte D
Int J Mol Sci 2023 Nov 23;24(23) doi: 10.3390/ijms242316668. PMID: 38068989Free PMC Article
Eosinophilic granulomatosis with polyangiitis.
Villa-Forte A
Postgrad Med 2023 Jan;135(sup1):52-60. Epub 2022 Dec 5 doi: 10.1080/00325481.2022.2134624. PMID: 36259957
Granulomatosis with polyangiitis (Wegener's).
Puéchal X
Joint Bone Spine 2020 Dec;87(6):572-578. Epub 2020 Jun 17 doi: 10.1016/j.jbspin.2020.06.005. PMID: 32562697
Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment.
Comarmond C, Cacoub P
Autoimmun Rev 2014 Nov;13(11):1121-5. Epub 2014 Aug 20 doi: 10.1016/j.autrev.2014.08.017. PMID: 25149391
Diagnosis and classification of polyarteritis nodosa.
Hernández-Rodríguez J, Alba MA, Prieto-González S, Cid MC
J Autoimmun 2014 Feb-Mar;48-49:84-9. Epub 2014 Jan 28 doi: 10.1016/j.jaut.2014.01.029. PMID: 24485157

Therapy

Hypertrophic pachymeningitis in ANCA-associated vasculitis: Clinical and immunopathological features and insights.
Shimojima Y, Sekijima Y
Autoimmun Rev 2023 Jun;22(6):103338. Epub 2023 Apr 14 doi: 10.1016/j.autrev.2023.103338. PMID: 37062439
Granulomatosis with polyangiitis (Wegener's).
Puéchal X
Joint Bone Spine 2020 Dec;87(6):572-578. Epub 2020 Jun 17 doi: 10.1016/j.jbspin.2020.06.005. PMID: 32562697
Polyarteritis nodosa.
Forbess L, Bannykh S
Rheum Dis Clin North Am 2015;41(1):33-46, vii. doi: 10.1016/j.rdc.2014.09.005. PMID: 25399938
Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment.
Comarmond C, Cacoub P
Autoimmun Rev 2014 Nov;13(11):1121-5. Epub 2014 Aug 20 doi: 10.1016/j.autrev.2014.08.017. PMID: 25149391
Diagnosis and classification of polyarteritis nodosa.
Hernández-Rodríguez J, Alba MA, Prieto-González S, Cid MC
J Autoimmun 2014 Feb-Mar;48-49:84-9. Epub 2014 Jan 28 doi: 10.1016/j.jaut.2014.01.029. PMID: 24485157

Prognosis

Hypertrophic pachymeningitis in ANCA-associated vasculitis: Clinical and immunopathological features and insights.
Shimojima Y, Sekijima Y
Autoimmun Rev 2023 Jun;22(6):103338. Epub 2023 Apr 14 doi: 10.1016/j.autrev.2023.103338. PMID: 37062439
Eosinophilic granulomatosis with polyangiitis.
Villa-Forte A
Postgrad Med 2023 Jan;135(sup1):52-60. Epub 2022 Dec 5 doi: 10.1080/00325481.2022.2134624. PMID: 36259957
Granulomatosis with polyangiitis (Wegener's).
Puéchal X
Joint Bone Spine 2020 Dec;87(6):572-578. Epub 2020 Jun 17 doi: 10.1016/j.jbspin.2020.06.005. PMID: 32562697
Polyarteritis Nodosa Neurologic Manifestations.
de Boysson H, Guillevin L
Neurol Clin 2019 May;37(2):345-357. Epub 2019 Mar 16 doi: 10.1016/j.ncl.2019.01.007. PMID: 30952413
Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment.
Comarmond C, Cacoub P
Autoimmun Rev 2014 Nov;13(11):1121-5. Epub 2014 Aug 20 doi: 10.1016/j.autrev.2014.08.017. PMID: 25149391

Clinical prediction guides

Hypertrophic pachymeningitis in ANCA-associated vasculitis: Clinical and immunopathological features and insights.
Shimojima Y, Sekijima Y
Autoimmun Rev 2023 Jun;22(6):103338. Epub 2023 Apr 14 doi: 10.1016/j.autrev.2023.103338. PMID: 37062439
Pathogenesis of ANCA-Associated Pulmonary Vasculitis.
Alba MA, Jennette JC, Falk RJ
Semin Respir Crit Care Med 2018 Aug;39(4):413-424. Epub 2018 Nov 7 doi: 10.1055/s-0038-1673386. PMID: 30404109Free PMC Article
Churg-Strauss syndrome.
Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M
Autoimmun Rev 2015 Apr;14(4):341-8. Epub 2014 Dec 11 doi: 10.1016/j.autrev.2014.12.004. PMID: 25500434
Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment.
Comarmond C, Cacoub P
Autoimmun Rev 2014 Nov;13(11):1121-5. Epub 2014 Aug 20 doi: 10.1016/j.autrev.2014.08.017. PMID: 25149391
Churg-Strauss syndrome.
Pagnoux C, Guilpain P, Guillevin L
Curr Opin Rheumatol 2007 Jan;19(1):25-32. doi: 10.1097/BOR.0b013e3280119854. PMID: 17143092

Recent systematic reviews

Efficacy of Rituximab on Refractory Organ Involvements in Granulomatosis with Polyangiitis: A Systematic Review of Case Reports.
Hajishah H, Amini MJ, Chadeganipour AS, Salehi SA, Kazemi D
Curr Rheumatol Rev 2024;20(3):270-283. doi: 10.2174/0115733971263964231020072640. PMID: 37907486
Biopsy-proven kidney involvement in hypocomplementemic urticarial vasculitis.
Corthier A, Jachiet M, Bertin D, Servais A, Barbet C, Bigot A, Doutre MS, Bessis D, Bouffandeau A, Moranne O, Jarrot PA, Bardin N, Terrier B, Burtey S, Puéchal X, Daniel L, Jourde-Chiche N
BMC Nephrol 2022 Feb 16;23(1):67. doi: 10.1186/s12882-022-02689-8. PMID: 35172758Free PMC Article
Inflammatory muscle involvement in systemic vasculitis: A systematic review.
Conticini E, d'Alessandro M, Al Khayyat SG, D'Alessandro R, D'Ignazio E, Pata AP, Vallifuoco G, Falsetti P, Baldi C, Bardelli M, Gentileschi S, Fabiani C, Mazzei MA, Guarnieri A, Bargagli E, Cantarini L, Frediani B
Autoimmun Rev 2022 Mar;21(3):103029. Epub 2021 Dec 29 doi: 10.1016/j.autrev.2021.103029. PMID: 34971804
Therapeutic options for cutaneous polyarteritis nodosa: a systematic review.
Papachristodoulou E, Kakoullis L, Tiniakou E, Parperis K
Rheumatology (Oxford) 2021 Sep 1;60(9):4039-4047. doi: 10.1093/rheumatology/keab402. PMID: 33944902
Dermatological Manifestations in Pediatric Inflammatory Bowel Disease.
Diaconescu S, Strat S, Balan GG, Anton C, Stefanescu G, Ioniuc I, Stanescu AMA
Medicina (Kaunas) 2020 Aug 23;56(9) doi: 10.3390/medicina56090425. PMID: 32842528Free PMC Article

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