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Intracranial Leptomeningeal Lesion

MedGen UID:
415989
Concept ID:
C2827410
Finding

Definition

A non-neoplastic or neoplastic pathologic process affecting the leptomeninges of the brain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntracranial Leptomeningeal Lesion

Professional guidelines

PubMed

Ribas GA, de Mori LH, Freddi TAL, Oliveira LDS, de Souza SR, Corrêa DG
Neuroradiol J 2024 Dec;37(6):705-722. Epub 2024 May 4 doi: 10.1177/19714009241252625. PMID: 38703015Free PMC Article
Pan K, Concannon K, Li J, Zhang J, Heymach JV, Le X
Nat Rev Clin Oncol 2023 Oct;20(10):716-732. Epub 2023 Aug 17 doi: 10.1038/s41571-023-00808-4. PMID: 37592034Free PMC Article
Del Brutto OH, Nash TE, White AC Jr, Rajshekhar V, Wilkins PP, Singh G, Vasquez CM, Salgado P, Gilman RH, Garcia HH
J Neurol Sci 2017 Jan 15;372:202-210. Epub 2016 Nov 21 doi: 10.1016/j.jns.2016.11.045. PMID: 28017213

Recent clinical studies

Etiology

Yao T, Zeng Q, Xie Y, Bi F, Zhang L, Xiao B, Zhou J
Mult Scler Relat Disord 2022 Apr;60:103727. Epub 2022 Mar 5 doi: 10.1016/j.msard.2022.103727. PMID: 35320766
Bahranifard B, Mehdizadeh S, Hamidi A, Khosravi A, Emami R, Mirzaei K, Nemati R, Nemati F, Assadi M, Gholamrezanezhad A
Neuroradiol J 2022 Feb;35(1):3-24. Epub 2021 Jul 5 doi: 10.1177/19714009211029177. PMID: 34224248Free PMC Article
Ruggieri M, Polizzi A, Catanzaro S, Bianco ML, Praticò AD, Di Rocco C
Childs Nerv Syst 2020 Oct;36(10):2571-2596. Epub 2020 Oct 13 doi: 10.1007/s00381-020-04770-9. PMID: 33048248
Grady C, Gesteira Benjamin C, Kondziolka D
Handb Clin Neurol 2017;143:125-131. doi: 10.1016/B978-0-444-63640-9.00012-6. PMID: 28552134
Sobol U, Stiff P
Handb Clin Neurol 2014;120:1083-99. doi: 10.1016/B978-0-7020-4087-0.00073-5. PMID: 24365373

Diagnosis

Kurokawa R, Kurokawa M, Isshiki S, Harada T, Nakaya M, Baba A, Naganawa S, Kim J, Bapuraj J, Srinivasan A, Abe O, Moritani T
Radiographics 2023 Aug;43(9):e230039. doi: 10.1148/rg.230039. PMID: 37535461
Ruggieri M, Polizzi A, Catanzaro S, Bianco ML, Praticò AD, Di Rocco C
Childs Nerv Syst 2020 Oct;36(10):2571-2596. Epub 2020 Oct 13 doi: 10.1007/s00381-020-04770-9. PMID: 33048248
Del Brutto OH, Nash TE, White AC Jr, Rajshekhar V, Wilkins PP, Singh G, Vasquez CM, Salgado P, Gilman RH, Garcia HH
J Neurol Sci 2017 Jan 15;372:202-210. Epub 2016 Nov 21 doi: 10.1016/j.jns.2016.11.045. PMID: 28017213
Smirniotopoulos JG, Murphy FM, Rushing EJ, Rees JH, Schroeder JW
Radiographics 2007 Mar-Apr;27(2):525-51. doi: 10.1148/rg.272065155. PMID: 17374867
Makkar HS, Frieden IJ
Semin Cutan Med Surg 2004 Jun;23(2):138-44. doi: 10.1016/j.sder.2004.01.007. PMID: 15295923

Therapy

Pérez-García JM, Vaz Batista M, Cortez P, Ruiz-Borrego M, Cejalvo JM, de la Haba-Rodriguez J, Garrigós L, Racca F, Servitja S, Blanch S, Gion M, Nave M, Fernández-Abad M, Martinez-Bueno A, Llombart-Cussac A, Sampayo-Cordero M, Malfettone A, Cortés J, Braga S
Neuro Oncol 2023 Jan 5;25(1):157-166. doi: 10.1093/neuonc/noac144. PMID: 35639825Free PMC Article
Sudmeier L, Tian S, Higgins KA
Curr Treat Options Oncol 2021 Jul 2;22(9):77. doi: 10.1007/s11864-021-00871-y. PMID: 34213649
Tolaney SM, Sahebjam S, Le Rhun E, Bachelot T, Kabos P, Awada A, Yardley D, Chan A, Conte P, Diéras V, Lin NU, Bear M, Chapman SC, Yang Z, Chen Y, Anders CK
Clin Cancer Res 2020 Oct 15;26(20):5310-5319. Epub 2020 Jul 21 doi: 10.1158/1078-0432.CCR-20-1764. PMID: 32694159
Mack F, Baumert BG, Schäfer N, Hattingen E, Scheffler B, Herrlinger U, Glas M
Cancer Treat Rev 2016 Feb;43:83-91. Epub 2015 Dec 24 doi: 10.1016/j.ctrv.2015.12.004. PMID: 26827696
Nowak DA, Widenka DC
J Neurol 2001 May;248(5):363-72. doi: 10.1007/s004150170175. PMID: 11437156

Prognosis

Pan K, Concannon K, Li J, Zhang J, Heymach JV, Le X
Nat Rev Clin Oncol 2023 Oct;20(10):716-732. Epub 2023 Aug 17 doi: 10.1038/s41571-023-00808-4. PMID: 37592034Free PMC Article
Nagai Yamaki V, de Souza Godoy LF, Alencar Bandeira G, Tavares Lucato L, Correa Lordelo G, Fontoura Solla DJ, Santana Neville I, Jacobsen Teixeira M, Silva Paiva W
Neuroradiology 2021 Aug;63(8):1215-1225. Epub 2021 Jan 18 doi: 10.1007/s00234-021-02632-y. PMID: 33459822
Burstein F, Seier H, Hudgins PA, Zapiach L
J Craniofac Surg 2005 Sep;16(5):874-6. doi: 10.1097/01.scs.0000181050.06696.4d. PMID: 16192875
Makkar HS, Frieden IJ
Semin Cutan Med Surg 2004 Jun;23(2):138-44. doi: 10.1016/j.sder.2004.01.007. PMID: 15295923
Di Rocco F, Sabatino G, Koutzoglou M, Battaglia D, Caldarelli M, Tamburrini G
Childs Nerv Syst 2004 Jan;20(1):23-8. Epub 2003 Oct 24 doi: 10.1007/s00381-003-0835-9. PMID: 14576958

Clinical prediction guides

Rahman RK, Majmundar N, Ghani H, San A, Koirala M, Gajjar AA, Pappert A, Mazzola CA
Neurosurg Focus 2022 May;52(5):E8. doi: 10.3171/2022.2.FOCUS21791. PMID: 35535823
Bahranifard B, Mehdizadeh S, Hamidi A, Khosravi A, Emami R, Mirzaei K, Nemati R, Nemati F, Assadi M, Gholamrezanezhad A
Neuroradiol J 2022 Feb;35(1):3-24. Epub 2021 Jul 5 doi: 10.1177/19714009211029177. PMID: 34224248Free PMC Article
Mormina E, Granata F, Vinci SL, Coglitore A, Caragliano AA, Tessitore A, Longo M, Visalli C
Curr Med Imaging 2021;17(12):1391-1402. doi: 10.2174/1573405617666210527091109. PMID: 34047260
Tolaney SM, Sahebjam S, Le Rhun E, Bachelot T, Kabos P, Awada A, Yardley D, Chan A, Conte P, Diéras V, Lin NU, Bear M, Chapman SC, Yang Z, Chen Y, Anders CK
Clin Cancer Res 2020 Oct 15;26(20):5310-5319. Epub 2020 Jul 21 doi: 10.1158/1078-0432.CCR-20-1764. PMID: 32694159
Hatiboglu MA, Akdur K, Sawaya R
Neurosurg Rev 2020 Apr;43(2):483-495. Epub 2018 Jul 29 doi: 10.1007/s10143-018-1013-6. PMID: 30058049

Recent systematic reviews

Rahman RK, Majmundar N, Ghani H, San A, Koirala M, Gajjar AA, Pappert A, Mazzola CA
Neurosurg Focus 2022 May;52(5):E8. doi: 10.3171/2022.2.FOCUS21791. PMID: 35535823

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