Signal transducer and activator of transcription 3 (Q14912021)

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mammalian protein found in Mus musculus
  • acute phase response factor
  • Stat3
  • signal transducer and activator of transcription 3
  • Acute-phase response factor
edit
Language Label Description Also known as
English
Signal transducer and activator of transcription 3
mammalian protein found in Mus musculus
  • acute phase response factor
  • Stat3
  • signal transducer and activator of transcription 3
  • Acute-phase response factor

Statements

part of
molecular function
protein binding
determination method or standard
IPI
26 references
retrieved
9 May 2019
stated in
Conserved regulation of the Jak/STAT pathway by the endosomal protein asrij maintains stem cell potency
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
BART is essential for nuclear retention of STAT3
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Cross-talk between KLF4 and STAT3 regulates axon regeneration
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
A Stat3-interacting protein (StIP1) regulates cytokine signal transduction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Fer is a downstream effector of insulin and mediates the activation of signal transducer and activator of transcription 3 in myogenic cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Bioinformatics and cellular signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Crif1 is a novel transcriptional coactivator of STAT3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
SH2B1β interacts with STAT3 and enhances fibroblast growth factor 1-induced gene expression during neuronal differentiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
ECHS1 interacts with STAT3 and negatively regulates STAT3 signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
retrieved
9 May 2019
stated in
Physical and functional interactions between STAT3 and ZIP kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IPI
DNA binding
determination method or standard
IDA
IEA
ISO
8 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
cell component
cytoplasm
determination method or standard
IDA
IEA
ISO
10 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Expression of Stat3 in germ cells of developing and adult mouse ovaries and testes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Expression and activation of STAT proteins during mouse retina development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
nucleus
determination method or standard
IDA
IEA
ISO
14 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
14 February 2019
stated in
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Expression and activation of STAT proteins during mouse retina development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
STAT3 negatively regulates thyroid tumorigenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Effects of leptin and leukemia inhibitory factor on preimplantation development and STAT3 signaling of mouse embryos in vitro
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
nucleus
determination method or standard
IBA
IDA
IEA
ISO
15 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Effects of leptin and leukemia inhibitory factor on preimplantation development and STAT3 signaling of mouse embryos in vitro
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
STAT3 negatively regulates thyroid tumorigenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Expression and activation of STAT proteins during mouse retina development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IBA
biological process
leptin-mediated signaling pathway
determination method or standard
IDA
ISS
IEA
IMP
ISO
5 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
14 February 2019
stated in
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
14 February 2019
stated in
Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
positive regulation of transcription by RNA polymerase II
determination method or standard
IDA
IGI
IEA
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
14 February 2019
stated in
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IGI
retrieved
14 February 2019
stated in
Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
14 February 2019
stated in
The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
14 February 2019
stated in
Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
positive regulation of transcription, DNA-templated
determination method or standard
IDA
IEA
IMP
ISO
5 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
9 May 2019
stated in
Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
Innate Stat3-mediated induction of the antimicrobial protein Reg3γ is required for host defense against MRSA pneumonia
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
leptin-mediated signaling pathway
determination method or standard
IBA
IDA
IEA
IMP
ISO
ISS
6 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISS
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
9 May 2019
stated in
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)
GOA
curator
UniProt
UniProt protein ID
P42227
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IBA
positive regulation of transcription by RNA polymerase II
determination method or standard
IBA
IDA
IEA
IGI
ISO
9 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
ISO
retrieved
9 May 2019
stated in
Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IGI
retrieved
9 May 2019
stated in
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IGI
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IEA
retrieved
9 May 2019
stated in
The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42227
determination method or standard
IBA

Identifiers

 
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