跳转到内容

尚卡尔·巴拉苏布拉马尼安：修订间差异

维基百科，自由的百科全书
以互动方式浏览历史
←上一版本下一版本→
删除的内容 添加的内容
可视化wikitext
无编辑摘要
无编辑摘要
第58行： 第58行：
| pages = 170–1
| pages = 170–1
| doi = 10.1016/j.tibs.2013.02.006
| doi = 10.1016/j.tibs.2013.02.006
}}</ref>和剑桥大学化学系Herchel-Smith药物化学教授<ref name="www-shankar.ch.cam.ac.uk">{{cite web|title=University of Cambridge, 2013. ''The Balasubramanian Group.''|url=http://www-shankar.ch.cam.ac.uk}} [Accessed 4 April 2013].</ref><ref name="Yusuf Hamied Department of Chemistry">{{cite web | title=Professor Sir Shankar Balasubramanian FMedSci FRS | website=Yusuf Hamied Department of Chemistry | url=https://www.ch.cam.ac.uk/person/sb10031 | access-date=13 December 2021}}</ref> ，英国癌症研究所高级小组组长和剑桥三一学院研究员。<ref name="Trinity College Cambridge 2021_3">{{cite web | title=Master & Fellows | website=Trinity College Cambridge | date=10 November 2021 | url=https://www.trin.cam.ac.uk/fellows/master-fellows/ | access-date=13 December 2021}}</ref> 他因在核酸领域的贡献而知名。他是和biomodal（正式名称为Cambridge Epigenetix）的科学创始人。<ref name="Cambridge Epigenetix has a vision to improve healthcare through routine measurement of the epigenome. 2020">{{cite web |date=19 January 2020 |title=Shankar Balasubramanian |url=https://biomodal.com/team/shankar-balasubramanian/ |access-date=13 December 2021 |website=biomodal integrates multiple modes of biology from a single sample in a single experiment to provide transformative insights into health and disease.}}</ref><ref name=gov>{{cite web|archive-url=https://web.archive.org/web/20160706081324/https://beta.companieshouse.gov.uk/officers/Ba6y-nMuKv3KG3r7164IhB0Nrs8/appointments|archive-date=2016-07-06|url=https://beta.companieshouse.gov.uk/officers/Ba6y-nMuKv3KG3r7164IhB0Nrs8/appointments|website=companieshouse.gov.uk|publisher=[[Companies House]]|location=London|title=Shankar BALASUBRAMANIAN}}</ref>
}}</ref>和剑桥大学化学系Herchel-Smith药物化学教授<ref name="www-shankar.ch.cam.ac.uk">{{cite web|title=University of Cambridge, 2013. ''The Balasubramanian Group.''|url=http://www-shankar.ch.cam.ac.uk}} [Accessed 4 April 2013].</ref><ref name="Yusuf Hamied Department of Chemistry">{{cite web | title=Professor Sir Shankar Balasubramanian FMedSci FRS | website=Yusuf Hamied Department of Chemistry | url=https://www.ch.cam.ac.uk/person/sb10031 | access-date=13 December 2021}}</ref> ，英国癌症研究所高级小组组长和剑桥三一学院研究员。<ref name="Trinity College Cambridge 2021_3">{{cite web | title=Master & Fellows | website=Trinity College Cambridge | date=10 November 2021 | url=https://www.trin.cam.ac.uk/fellows/master-fellows/ | access-date=13 December 2021}}</ref> 他因在核酸领域的贡献而知名。他是Solexa和biomodal（正式名称为Cambridge Epigenetix）的科学创始人。<ref name="Cambridge Epigenetix has a vision to improve healthcare through routine measurement of the epigenome. 2020">{{cite web |date=19 January 2020 |title=Shankar Balasubramanian |url=https://biomodal.com/team/shankar-balasubramanian/ |access-date=13 December 2021 |website=biomodal integrates multiple modes of biology from a single sample in a single experiment to provide transformative insights into health and disease.}}</ref><ref name=gov>{{cite web|archive-url=https://web.archive.org/web/20160706081324/https://beta.companieshouse.gov.uk/officers/Ba6y-nMuKv3KG3r7164IhB0Nrs8/appointments|archive-date=2016-07-06|url=https://beta.companieshouse.gov.uk/officers/Ba6y-nMuKv3KG3r7164IhB0Nrs8/appointments|website=companieshouse.gov.uk|publisher=[[Companies House]]|location=London|title=Shankar BALASUBRAMANIAN}}</ref>


==早年==
==早年==
第71行： 第71行：
{{reflist}}
{{reflist}}


[[Category:英国生物化学家]]
[[Category:欧洲分子生物学组织会员]]
[[Category:盖尔德纳国际奖获得者]]
[[Category:盖尔德纳国际奖获得者]]

2024年10月9日 (三) 05:46的版本

教授
Shankar Balasubramanian爵士
FRS FMedSci（英语：Fellow of the Academy of Medical Sciences）
出生 (1966-09-30) 1966年9月30日（58歲）[1]
印度钦奈
国籍英国
母校剑桥大学
知名于
奖项
网站www.ch.cam.ac.uk/group/shankar https://www.cruk.cam.ac.uk/research-groups/balasubramanian-group
科学生涯
机构
论文Studies on the reaction mechanism of chorismate synthase（1992）
博士導師Chris Abell
博士生Julian Huppert[2][3]

尚卡尔·巴拉苏布拉马尼安，​英国化学家[4][5]和剑桥大学化学系Herchel-Smith药物化学教授[6][7] ，英国癌症研究所高级小组组长和剑桥三一学院研究员。[8] 他因在核酸领域的贡献而知名。他是Solexa和biomodal（正式名称为Cambridge Epigenetix）的科学创始人。[9][10]

早年

尚卡尔1966年出生于印度马德拉斯（今钦奈），1967年随父母移居英国。他在柴郡伦科恩郊外的一个村子长大，就读于Daresbury小学，然后升入Appleton Hall高中（后合并为Bridgewater高中）。1985至1988年，他在剑桥菲茨威廉学院学习理科，获本科学位，之后在Chris Abell指导下研究分支酸合酶的反应机制，1991年获博士学位。[11][12]

研究生涯

尚卡尔于1994年在剑桥大学开始了独立的学术生涯，此后一直担任学院讲师，然后担任大学讲师（1998年）、大学化学生物学讲师（2003年）和化学生物学教授（2007年）。他于2008年被任命为Herchel Smith药物化学教授。[13]

尚卡尔是核酸领域的权威学者，他主导了下一代测序方法——Solexa测序的发明，该方法为人类基因组的常规、准确、低成本测序奠定基础。他对非编码遗传元件的鉴定、阐明和操纵做出了贡献，特别是被称为G-四链体的四链结构。他利用小分子干预核酸功能的工作揭示了许多分子机制，对癌症研究有重大影响。[14]}}

参考资料

  1. ^ 1.0 1.1 Anon. https://www.ukwhoswho.com/view/article/oupww/whoswho/U256669 |chapter-url=缺少标题 (帮助)需要付费订阅. 英国名人录. ukwhoswho.com online Oxford University Press (布盧姆斯伯里出版公司旗下A & C Black). 2017. doi:10.1093/ww/9780199540884.013.256669.  需要订阅或英国公共图书馆会员资格
  2. ^ Huppert, J. L.; Balasubramanian, S. Prevalence of quadruplexes in the human genome. Nucleic Acids Research. 2005, 33 (9): 2908–2916. PMC 1140081 可免费查阅. PMID 15914667. doi:10.1093/nar/gki609. 
  3. ^ Huppert, Julian Leon. Studies on genomic G-quadruplexes. lib.cam.ac.uk (PhD论文) (University of Cambridge). 2005. OCLC 885437272. EThOS uk.bl.ethos.604822. 
  4. ^ Balasubramanian, S. From DNA to mountain climbing. Shankar Balasubramanian talks to Alison Stoddart about his research and other interests. Molecular BioSystems. 2007, 3 (5): B37. PMID 17582897. 
  5. ^ Balasubramanian, S. An interview with Shankar Balasubramanian. Trends in Biochemical Sciences. 2013, 38 (4): 170–1. PMID 23522090. doi:10.1016/j.tibs.2013.02.006. 
  6. ^ University of Cambridge, 2013. The Balasubramanian Group..  [Accessed 4 April 2013].
  7. ^ Professor Sir Shankar Balasubramanian FMedSci FRS. Yusuf Hamied Department of Chemistry. [13 December 2021]. 
  8. ^ Master & Fellows. Trinity College Cambridge. 10 November 2021 [13 December 2021]. 
  9. ^ Shankar Balasubramanian. biomodal integrates multiple modes of biology from a single sample in a single experiment to provide transformative insights into health and disease. 19 January 2020 [13 December 2021]. 
  10. ^ Shankar BALASUBRAMANIAN. companieshouse.gov.uk. London: Companies House. （原始内容存档于2016-07-06）. 
  11. ^ Balasubramanian, Shankar. Studies on the reaction mechanism of chorismate synthase. lib.cam.ac.uk (PhD论文) (University of Cambridge). 1991. OCLC 60112382. EThOS uk.bl.ethos.386780. 
  12. ^ Fitz alumni on top science list. Fitzwilliam College. 2014 [6 February 2014]. （原始内容存档于22 February 2014）. 
  13. ^ Home. Balasubramanian Group. 19 August 2016 [13 December 2021]. 
  14. ^ Shankar Balasubramanian | Royal Society. 
检索自“https://zh.wikipedia.org/w/index.php?title=尚卡尔·巴拉苏布拉马尼安&oldid=84518225”