FAM13C

FAM13C
Identifikatori
Aliasi	FAM13C
Vanjski ID-jevi	MGI: 1918971 HomoloGene: 11490 GeneCards: FAM13C
Lokacija gena (čovjek) Hrom. Hromosom 10 (čovjek) Bend 10q21.1 Početak 59,246,130 bp Kraj 59,363,181 bp
Lokacija gena (miš) Hrom. Hromosom 10 (miš) Bend 10|10 B5.3 Početak 70,276,311 bp Kraj 70,394,566 bp
Ortolozi
Vrste	Čovjek	Miš
Entrez	220965	71721
Ensembl	ENSG00000148541	ENSMUSG00000043259
UniProt	Q8NE31	Q9DBR2
RefSeq (mRNK)	NM_001001971 NM_001143773 NM_001166698 NM_001347840 NM_001347842 NM_001347843 NM_001347844 NM_001347845 NM_001347846 NM_001347847 NM_001347848 NM_001347849 NM_001347850 NM_001347851 NM_001347852 NM_198215	NM_001143776 NM_001143777 NM_024244 NM_001359551
RefSeq (bjelančevina)	NP_001001971 NP_001137245 NP_001160170 NP_001334769 NP_001334771 NP_001334772 NP_001334773 NP_001334774 NP_001334775 NP_001334776 NP_001334777 NP_001334778 NP_001334779 NP_001334780 NP_001334781 NP_937858	NP_001137248 NP_001137249 NP_077206 NP_001346480
Lokacija (UCSC)	Chr 10: 59.25 – 59.36 Mb	Chr 10: 70.28 – 70.39 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Član C porodice proteina sa sličnošću sekvence 13 je protein koji je kod ljudi kodiran genom FAM13C.

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 585 aminokiselina, а molekulska težina 65.727 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MFSCFCFSLQ		DNSFSSTTVT		ECDEDPVSLH		EDQTDCSSLR		DENNKENYPD
AGALVEEHAP		PSWEPQQQNV		EATVLVDSVL		RPSMGNFKSR		KPKSIFKAES
GRSHGESQET		EHVVSSQSEC		QVRAGTPAHE		SPQNNAFKCQ		ETVRLQPRID
QRTAISPKDA		FETRQDLNEE		EAAQVHGVKD		PAPASTQSVL		ADGTDSADPS
PVHKDGQNEA		DSAPEDLHSV		GTSRLLYHIT		DGDNPLLSPR		CSIFSQSQRF
NLDPESAPSP		PSTQQFMMPR		SSSRCSCGDG		KEPQTITQLT		KHIQSLKRKI
RKFEEKFEQE		KKYRPSHGDK		TSNPEVLKWM		NDLAKGRKQL		KELKLKLSEE
QGSAPKGPPR		NLLCEQPTVP		RENGKPEAAG		PEPSSSGEET		PDAALTCLKE
RREQLPPQED		SKVTKQDKNL		IKPLYDRYRI		IKQILSTPSL		IPTIQEEEDS
DEDRPQGSQQ		PSLADPASHL		PVGDHLTYSN		ETEPVRALLP		DEKKEVKPPA
LSMSNLHEAT		MPVLLDHLRE		TRADKKRLRK		ALREFEEQFF		KQTGRSPQKE
DRIPMADEYY		EYKHIKAKLR		LLEVLISKQD		VAKTI

Dopunska literatura

• Wu JH, Lemaitre RN, Manichaikul A, Guan W, Tanaka T, Foy M, Kabagambe EK, Djousse L, Siscovick D, Fretts AM, Johnson C, King IB, Psaty BM, McKnight B, Rich SS, Chen YD, Nettleton JA, Tang W, Bandinelli S, Jacobs DR, Browning BL, Laurie CC, Gu X, Tsai MY, Steffen LM, Ferrucci L, Fornage M, Mozaffarian D (april 2013). "Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium". Circulation: Cardiovascular Genetics. 6 (2): 171–83. doi:10.1161/CIRCGENETICS.112.964619. PMC 3891054. PMID 23362303.
• Karasik D, Hsu YH, Zhou Y, Cupples LA, Kiel DP, Demissie S (juli 2010). "Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study". Journal of Bone and Mineral Research. 25 (7): 1555–63. doi:10.1002/jbmr.38. PMC 3153998. PMID 20200953.