calcilyticとは 意味・読み方・使い方

名詞

calcilytic ‎(複数形 calcilytics)

1. Any antagonist of a calcium-sensing receptor; especially such a drug used for the treatment of osteoporosis
   • 2015 September 17, “Inhibition of Excessive Cell Proliferation by Calcilytics in Idiopathic Pulmonary Arterial Hypertension”^[1], PLOS ONE, DOI:10.1371/journal.pone.0138384: 

     Treatment with NPS2143, an antagonist of CaSR or calcilytic, clearly suppressed the cell proliferation in a concentration-dependent manner (IC 50 = 2.64 μM) in IPAH-PASMCs, but not in normal and CTEPH PASMCs. Another calcilytic, Calhex 231, which is structurally unrelated to NPS2143, also concentration-dependently inhibited the excessive proliferation of IPAH-PASMCs (IC 50 = 1.89 μM).