Eastern North Macedonia is the region of North Macedonia lying to the east of the Povardarie region.

Cities

• 1 Berovo (Берово) – a little town in an area with charming villages and serene nature
• 2 Bogdanci (Богданци)
• 3 Delčevo (Делчево, Delchevo)
• 4 Dojran (Дојран) – situated on Lake Dojran
• 5 Gevgelija (Гевгелија)
• 6 Kočani (Кочани, Kochani)
• 7 Kratovo (Кратово)
• 8 Kriva Palanka (Крива Паланка)
• 9 Kumanovo (Куманово)
• 10 Makedonska Kamenica (Македонска Каменица)
• 11 Pehčevo (Пехчево, Pehchevo)
• 12 Probištip (Пробиштип, Probishtip)
• 13 Radoviš (Радовиш, Radovish)
• 14 Sveti Nikole (Свети Николе)
• 15 Štip (Штип, Shtip)
• 16 Strumica (Струмица) – largest city in the region
• 17 Valandovo (Валандово)
• 18 Vinica (Виница)

Other destinations

• 1 Bosilovo (Босилово)
• 2 Novo Selo (Ново Село) – home to Macedonia's two best-known waterfalls, including its tallest