Chromosoma 11 (homo)
Chromosoma 11 humanum est uno ex viginti tribus paribus in hominibus, quibus de consuetudine horum chromosomatum duo exempla sunt. Hoc chromosoma portat 134 452 384 bases conexas, quod est 4,4 centesimae omnium in genomate[1]. Plures morbi genetici e mutationibus chromosomatis 11 oriuntur.
Gena
[recensere | fontem recensere]Inter alia haec gena in chromosomate humani 11 locata sunt:
- ACAT1 — acetyl-coenzymi A acetyltransferasis 1: 11q22.3-23.1
- APOA4 — apolipoproteinum: 11q23
- BACE - beta-secretasis 1: 11q23.3
- CASP — caspasis 1 (11q22.3)
- GRIA4 — receptorium ionotropicum glutamati (AMPA) 4 (11q22-23)
- GRIK4 — receptorium ionotropicum glutamati (Kainatum) 4 (11q22.3)
- GRM5 - Receptorium metabotropicum glutamati
- CHRM1 - Receptorium acetylcholini muscarinicum M1 (M1R) 11q12.3
- SERPING1 — inhibitor esterasis C1 (angiooedema hereditarium): 11q12.1
- TH — tyrosini hydroxylasis[2]: 11p15.5[3], synthesis biologicae dopamini.
Notae
[recensere | fontem recensere]- ↑ Descriptio chromosomatis 11.
- ↑ Powell JF, Boni C, Lamouroux A, Craig IW, Mallet J (1984). "Assignment of the human tyrosine hydroxylase gene to chromosome 11". FEBS Lett 175: 37-40
- ↑ Locus geni TH https://ghr.nlm.nih.gov/gene/TH#location
Nexus interni
Nexus externi
[recensere | fontem recensere]- Chromosoma 11 et Human Genome Project: http://web.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/chromo11.shtml
Chromosomata hominis
