Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1843 1
1856 1
1863 1
1870 2
1883 1
1893 1
1900 1
1904 1
1912 1
1922 1
1926 1
1931 1
1933 1
1940 1
1941 1
1942 1
1946 3
1947 2
1949 1
1950 6
1951 4
1952 3
1953 1
1954 2
1955 3
1956 3
1957 7
1958 6
1959 9
1960 10
1961 15
1962 11
1963 26
1964 28
1965 24
1966 15
1967 6
1968 16
1969 24
1970 22
1971 19
1972 28
1973 28
1974 55
1975 125
1976 166
1977 193
1978 231
1979 334
1980 417
1981 504
1982 675
1983 975
1984 1136
1985 1614
1986 1923
1987 2358
1988 2998
1989 3809
1990 4577
1991 5636
1992 6703
1993 7892
1994 9268
1995 10319
1996 11003
1997 12176
1998 13468
1999 14696
2000 16151
2001 16749
2002 17253
2003 18514
2004 20355
2005 21544
2006 23274
2007 24463
2008 25339
2009 27385
2010 29632
2011 31886
2012 34161
2013 35989
2014 37115
2015 38256
2016 39434
2017 40721
2018 41949
2019 43790
2020 48929
2021 54499
2022 53713
2023 51701
2024 40257
2025 24

Text availability

Article attribute

Article type

Publication date

Search Results

855,573 results

Results by year

Filters applied: . Clear all
Page 1
CDD/SPARCLE: the conserved domain database in 2020.
Lu S, Wang J, Chitsaz F, Derbyshire MK, Geer RC, Gonzales NR, Gwadz M, Hurwitz DI, Marchler GH, Song JS, Thanki N, Yamashita RA, Yang M, Zhang D, Zheng C, Lanczycki CJ, Marchler-Bauer A. Lu S, et al. Nucleic Acids Res. 2020 Jan 8;48(D1):D265-D268. doi: 10.1093/nar/gkz991. Nucleic Acids Res. 2020. PMID: 31777944 Free PMC article.
CDD offers both an archive of pre-computed domain annotations as well as live search services for both single protein or nucleotide queries and larger sets of protein query sequences. CDD staff has continued to characterize protein families via conserv …
CDD offers both an archive of pre-computed domain annotations as well as live search services for both single protein or nucle …
Tandem domain swapping: determinants of multidomain protein misfolding.
Lafita A, Tian P, Best RB, Bateman A. Lafita A, et al. Curr Opin Struct Biol. 2019 Oct;58:97-104. doi: 10.1016/j.sbi.2019.05.012. Epub 2019 Jun 28. Curr Opin Struct Biol. 2019. PMID: 31260947 Free PMC article. Review.
Tandem homologous domains in proteins are susceptible to misfolding through the formation of domain swaps, non-native conformations involving the exchange of equivalent structural elements between adjacent domains. ...At present, the number of studies on tand …
Tandem homologous domains in proteins are susceptible to misfolding through the formation of domain swaps, non-native conforma …
Structural Evolution of TIR-Domain Signalosomes.
Nimma S, Gu W, Maruta N, Li Y, Pan M, Saikot FK, Lim BYJ, McGuinness HY, Zaoti ZF, Li S, Desa S, Manik MK, Nanson JD, Kobe B. Nimma S, et al. Front Immunol. 2021 Nov 17;12:784484. doi: 10.3389/fimmu.2021.784484. eCollection 2021. Front Immunol. 2021. PMID: 34868065 Free PMC article. Review.
TIR (Toll/interleukin-1 receptor/resistance protein) domains are cytoplasmic domains widely found in animals and plants, where they are essential components of the innate immune system. A key feature of TIR-domain function in signaling is weak and tran …
TIR (Toll/interleukin-1 receptor/resistance protein) domains are cytoplasmic domains widely found in animals and plants …
Domain swapping of death domain superfamily: Alternative strategy for dimerization.
Park HH. Park HH. Int J Biol Macromol. 2019 Oct 1;138:565-572. doi: 10.1016/j.ijbiomac.2019.07.139. Epub 2019 Jul 24. Int J Biol Macromol. 2019. PMID: 31351149 Review.
The role of death domain (DD) protein-mediated inter-protein interactions in cell death and immune cell signaling have been extensively investigated as they are tentative targets for therapeutic interventions and are involved in signal transduction. ...Recent …
The role of death domain (DD) protein-mediated inter-protein interactions in cell death and immune cell signaling have …
Small-molecule tools for YEATS domain proteins.
Erb MA. Erb MA. Curr Opin Chem Biol. 2023 Dec;77:102404. doi: 10.1016/j.cbpa.2023.102404. Epub 2023 Nov 3. Curr Opin Chem Biol. 2023. PMID: 37924571 Review.
Chromatin reader domains are protein folds that bind to post-translational modifications of histones and other chromatin-associated proteins. ...Four human proteins harbor a YEATS domain, and each is present in protein complexes that regulate chromatin …
Chromatin reader domains are protein folds that bind to post-translational modifications of histones and other chromatin-assoc …
Searching protein space for ancient sub-domain segments.
Kolodny R. Kolodny R. Curr Opin Struct Biol. 2021 Jun;68:105-112. doi: 10.1016/j.sbi.2020.11.006. Epub 2021 Jan 18. Curr Opin Struct Biol. 2021. PMID: 33476896 Free article. Review.
Characterizing these may provide clues to the emergence of domains. Particularly interesting are themes that are reused across dissimilar contexts, that is, where the rest of the protein domain differs. We survey computational studies identifying reused theme …
Characterizing these may provide clues to the emergence of domains. Particularly interesting are themes that are reused across dissim …
Titin N2A Domain and Its Interactions at the Sarcomere.
Adewale AO, Ahn YH. Adewale AO, et al. Int J Mol Sci. 2021 Jul 15;22(14):7563. doi: 10.3390/ijms22147563. Int J Mol Sci. 2021. PMID: 34299183 Free PMC article. Review.
Titin's multiple functions are in part attributed to its large size and modular structures that interact with a myriad of protein partners. Among titin's domains, the N2A element is one of titin's unique segments that contributes to titin's functions in compliance, …
Titin's multiple functions are in part attributed to its large size and modular structures that interact with a myriad of protein par …
Pleckstrin Homology [PH] domain, structure, mechanism, and contribution to human disease.
Powis G, Meuillet EJ, Indarte M, Booher G, Kirkpatrick L. Powis G, et al. Biomed Pharmacother. 2023 Sep;165:115024. doi: 10.1016/j.biopha.2023.115024. Epub 2023 Jul 1. Biomed Pharmacother. 2023. PMID: 37399719 Free article. Review.
The pleckstrin homology [PH] domain is a structural fold found in more than 250 proteins making it the 11th most common domain in the human proteome. 25% of family members have more than one PH domain and some PH domains are split by one, or several ot …
The pleckstrin homology [PH] domain is a structural fold found in more than 250 proteins making it the 11th most common domain …
Understanding protein domain-swapping using structure-based models of protein folding.
Mascarenhas NM, Gosavi S. Mascarenhas NM, et al. Prog Biophys Mol Biol. 2017 Sep;128:113-120. doi: 10.1016/j.pbiomolbio.2016.09.013. Epub 2016 Nov 17. Prog Biophys Mol Biol. 2017. PMID: 27867057 Free PMC article. Review.
In domain-swapping, two or more identical protein monomers exchange structural elements and fold into dimers or multimers whose units are structurally similar to the original monomer. Domain-swapping is of biotechnological interest because inhibiting domai …
In domain-swapping, two or more identical protein monomers exchange structural elements and fold into dimers or multimers whos …
The LL-37 domain: A clue to cathelicidin immunomodulatory response?
Leite ML, Duque HM, Rodrigues GR, da Cunha NB, Franco OL. Leite ML, et al. Peptides. 2023 Jul;165:171011. doi: 10.1016/j.peptides.2023.171011. Epub 2023 Apr 15. Peptides. 2023. PMID: 37068711 Review.
In this review, we will address the role of the LL-37 domain and its SK-24, IV-20, FK-13 and LL-37 fragments in the immunity response. Other cathelicidins also share structural and functional characteristics with the LL-37 domain, suggesting that these fragments may …
In this review, we will address the role of the LL-37 domain and its SK-24, IV-20, FK-13 and LL-37 fragments in the immunity response …
855,573 results
You have reached the last available page of results. Please see the User Guide for more information.

Searches related to "domain"