Eltrombopag

KP Garnock-Jones, SJ Keam - Drugs, 2009 - Springer
eltrombopag).[11] There was no evidence of rebound thrombocytopenia after ceasing
eltrombopag … within the normal range at baseline and were unaffected by eltrombopag

[HTML][HTML] Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura

JB Bussel, G Cheng, MN Saleh, B Psaila… - … England Journal of …, 2007 - Mass Medical Soc
eltrombopag … of eltrombopag than in the other eltrombopag groups. After 1 week of treatment
(day 8), more than 10% of patients in the groups receiving 50 mg or 75 mg of eltrombopag

Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 study

G Cheng, MN Saleh, C Marcher, S Vasey, B Mayer… - The Lancet, 2011 - thelancet.com
… to once daily eltrombopag versus … eltrombopag needed rescue treatment compared with
25 (40%) patients receiving placebo (p=0·001). Three (2%) patients receiving eltrombopag had …

Eltrombopag added to immunosuppression in severe aplastic anemia

R Peffault de Latour, A Kulasekararaj… - … England Journal of …, 2022 - Mass Medical Soc
Background A single-group, phase 1–2 study indicated that eltrombopag improved the
efficacy of standard immunosuppressive therapy that entailed horse antithymocyte globulin (ATG) …

Eltrombopag

JB Bussel, MP Pinheiro - Hematopoietic Growth Factors in Oncology, 2010 - Springer
… Proliferation and differentiation induced by eltrombopag. a Proliferation of BAF3/hTpoR
cells induced by eltrombopag after 48 h of treatment; the dotted line represents the activity of …

Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo …

JB Bussel, D Provan, T Shamsi, G Cheng, B Psaila… - The Lancet, 2009 - thelancet.com
Background Eltrombopag is an oral, non-peptide, thrombopoietin-receptor agonist that
stimulates thrombopoiesis, leading to increased platelet production. This study assessed the …

Safety and efficacy of eltrombopag for treatment of chronic immune thrombocytopenia: results of the long-term, open-label EXTEND study

MN Saleh, JB Bussel, G Cheng, O Meyer… - Blood, The Journal …, 2013 - ashpublications.org
Eltrombopag increases and maintains hemostatic platelet counts; however, to date, … EXTEND
(Eltrombopag eXTENded Dosing) study evaluates the safety and efficacy of eltrombopag in …

Eltrombopag in immune thrombocytopenia: efficacy review and update on drug safety

JR Gonzalez-Porras… - Therapeutic Advances in …, 2018 - journals.sagepub.com
… the experience reported using eltrombopag in ITP, … of eltrombopag in particular situations
will also be covered. The experience reported so far permits us to suggest that eltrombopag

Eltrombopag and improved hematopoiesis in refractory aplastic anemia

MJ Olnes, P Scheinberg, KR Calvo… - … England Journal of …, 2012 - Mass Medical Soc
Eltrombopag (Promacta) is an oral thrombopoietin mimetic … Eltrombopag increases platelet
counts in healthy persons and … We hypothesized that eltrombopag might have activity in …

Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia

NH Afdhal, EG Giannini, G Tayyab… - … England Journal of …, 2012 - Mass Medical Soc
Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated the efficacy
of eltrombopag for increasing platelet counts and reducing the need for platelet transfusions in …