Dokozanol

Dokozanol
Naziv po klasifikaciji	Dokozan-1-ol
Drugi nazivi	Behenski alcohol; Behenil alcohol; 1-Dokozanol; n-Dokozanol; Dokozil alkohol; Emeri 3304; Loksiol VPG 1451
Identifikacija
CAS registarski broj	661-19-8
PubChem	12620
ChemSpider	12100
UNII	9G1OE216XY
EINECS broj	211-546-6
DrugBank	DB00632
KEGG	D03884
MeSH	docosanol
ChEBI	31000
ChEMBL	CHEMBL1200453
RTECS registarski broj toksičnosti	JR1315000
ATC code	D06BB11
Bajlštajn	1770470
Jmol-3D slike	Slika 1
SMILES
	CCCCCCCCCCCCCCCCCCCCCCO
InChI
	InChI=1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3 ; Kod: NOPFSRXAKWQILS-UHFFFAOYSA-N InChI=1/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3; Kod: NOPFSRXAKWQILS-UHFFFAOYAB
Svojstva
Molekulska formula	C22H46O
Molarna masa	326.6 g mol−1
Tačka topljenja	70 °C, 343 K, 158 °F
Tačka ključanja	180 °C, 453 K, 356 °F (na 29 Pa)
log P	10,009
Farmakologija
Načini upotrebe	Topikalno
Legalni status	; OTC(SAD)
Kategorija; trudnoće
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Dokozanol (behenski alkohol) je zasićeni masni alkohol^[8] koji se koristi kao sredstvo za razmekšavanje, emulgator, i zgušnjivač u kozmetici,^[9]^[10]^[11] prehrambeni suplement (pojedinačno i kao sastojak polikozanola), i od nedavno kao lek, Abreva,^[12] koji je odobren kao antivirusni lek za umanjenje dužine trajanja groznice na usnama uzrokovane herpes simpleks virusom.

Reference

↑ ^1,0 ^1,1 ^1,2 ^1,3 „Docosan-1-ol (CHEBI:31000)”. Chemical Entities of Biological Interest (ChEBI). UK: European Bioinformatics Institute.
↑ ^2,0 ^2,1 ^2,2 Chemical Book: 1-Docosanol
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Katz DH, Marcelletti JF, Khalil MH, Pope LE, Katz LR (December 1991). „Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex”. Proc. Natl. Acad. Sci. U.S.A. 88 (23): 10825–9. DOI:10.1073/pnas.88.23.10825. PMC 53024. PMID 1660151.
↑ Fleur's Cosmetics Canada
↑ „Korres USA”. Arhivirano iz originala na datum 2009-08-04. Pristupljeno 2014-04-11.
↑ Avalon Organics
↑ „mediLexicon: Docosanol”. Arhivirano iz originala na datum 2013-03-10. Pristupljeno 2014-04-11.

Povezano

Behenska kiselina

Spoljašnje veze

Portal Hemija

[docosan-1-ol_(CHEBI:31000)-1] 1,0 ^1,1 ^1,2 ^1,3 „Docosan-1-ol (CHEBI:31000)”. Chemical Entities of Biological Interest (ChEBI). UK: European Bioinformatics Institute.

[chemical_book-2] 2,0 ^2,1 ^2,2 Chemical Book: 1-Docosanol

[3] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[4] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[5] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[6] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[7] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[pmid1660151-8] Katz DH, Marcelletti JF, Khalil MH, Pope LE, Katz LR (December 1991). „Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex”. Proc. Natl. Acad. Sci. U.S.A. 88 (23): 10825–9. DOI:10.1073/pnas.88.23.10825. PMC 53024. PMID 1660151.

[9] Fleur's Cosmetics Canada

[10] „Korres USA”. Arhivirano iz originala na datum 2009-08-04. Pristupljeno 2014-04-11.

[11] Avalon Organics

[12] „mediLexicon: Docosanol”. Arhivirano iz originala na datum 2013-03-10. Pristupljeno 2014-04-11.

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p r u Alkoholi
(0°)	Metanol
Primarni alkoholi (1°)	Etanol • Propan-1-ol • Butanol/Izobutanol • 1-Pentanol • 1-Heksanol • 1-Heptanol Masni alkohol: 1-Oktanol (C₈) • 1-Nonanol (C₉) • 1-Dekanol (C₁₀) • Undekanol (C₁₁) • Dodekanol (C₁₂) • 1-Tetradekanol (C₁₄) • Cetil alkohol (C₁₆) • Stearil alkohol (C₁₈) • Arahidil alkohol (C₂₀) • Dokozanol (C₂₂) • Tetrakozanol (C₂₄) • Heksakozanol (C₂₆) • Oktanozol (C₂₈) • Triakontanol (C₃₀) Polikozanol
Sekondarni alkoholi (2°)	Izopropil alkohol • 2-Butanol • 2-Heksanol • Cikloheksanol
Tercijarni alkoholi (3°)	tert-Butanol • 2-Metil-2-butanol
Biohemijske familije: Ugljeni hidrati (Glikozidi,Alkoholi) • Lipidi (Steroidi,Fosfolipidi,Glikolipidi,Masne kiseline,Tetrapiroli) • Proteini (Aminokiseline,Peptidi,Glikoproteini) • Nukleobaze/Nukleinske kiseline