SIB-1553A
{{Chembox-lat | ImageFile = SIB-1553A.svg | ImageSize = 200px | ImageAlt = | IUPACName = (R/S)-4-{[2-(1-Metil-2-pirolidinil)etil]tio}fenol hidrohlorid | OtherNames = | Section1 = ! colspan=2 style="background: #f8eaba; text-align: center;" |Identifikacija
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3D model (Jmol)
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- OC1=CC=C(SCCC2CCCN2C)C=C1
|- | Section2 = ! colspan=2 style="background: #f8eaba; text-align: center;" |Svojstva
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| C13H19NOS
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| 237,36 g·mol−1
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SIB-1553A je agonist nikotinskih acetilholinskih receptora koji je selektivan za receptore sa β4 podjedinicom. Administriranje SIB-1553A poboljšava memoriju i pažnju u modelu Parkinsonove bolesti.[1]
Reference
уреди- ^ Schneider, JS (2003). „The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys”. Journal of Pharmacology and Experimental Therapeutics. 306 (1): 401—6. PMID 12721323. doi:10.1124/jpet.103.051912. Приступљено 19. 12. 2011.
