epithelial cell adhesion molecule (Q5383694)

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mammalian protein found in Homo sapiens

• adenocarcinoma-associated antigen
• hEGP314
• Epithelial cell surface antigen
• tumor-associated calcium signal transducer 1
• EGP
• epithelial cell adhesion molecule
• EGP314
• cell surface glycoprotein Trop-1
• KS 1/4 antigen
• human epithelial glycoprotein-2
• EPCAM
• membrane component, chromosome 4, surface marker (35kD glycoprotein)
• Epithelial glycoprotein
• KSA
• trophoblast cell surface antigen 1
• major gastrointestinal tumor-associated protein GA733-2
• epithelial glycoprotein 314

edit

Language	Label	Description	Also known as
English	epithelial cell adhesion molecule	mammalian protein found in Homo sapiens	adenocarcinoma-associated antigen hEGP314 Epithelial cell surface antigen tumor-associated calcium signal transducer 1 EGP epithelial cell adhesion molecule EGP314 cell surface glycoprotein Trop-1 KS 1/4 antigen human epithelial glycoprotein-2 EPCAM membrane component, chromosome 4, surface marker (35kD glycoprotein) Epithelial glycoprotein KSA trophoblast cell surface antigen 1 major gastrointestinal tumor-associated protein GA733-2 epithelial glycoprotein 314

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P16422

part of

Thyroglobulin type-1 superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P16422

Thyroglobulin type-1, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P16422

encoded by

EPCAM

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P16422

molecular function

protein-containing complex binding

determination method or standard

IDA

2 references

retrieved

26 September 2017

stated in

Nuclear signalling by tumour-associated antigen EpCAM

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IDA

retrieved

8 April 2019

stated in

Nuclear signalling by tumour-associated antigen EpCAM

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

protein binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IPI

cadherin binding involved in cell-cell adhesion

determination method or standard

IEA

IBA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IBA

cell component

integral component of membrane

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

lateral plasma membrane

determination method or standard

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

bicellular tight junction

determination method or standard

IDA

IEA

3 references

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

26 September 2017

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

26 September 2017

stated in

The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IDA

plasma membrane

determination method or standard

IDA

IEA

TAS

7 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

TAS

retrieved

8 April 2019

stated in

A murine cDNA encodes a pan-epithelial glycoprotein that is also expressed on plasma cells

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

retrieved

8 April 2019

stated in

The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

cell surface

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

cell junction

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

basolateral plasma membrane

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Spatial and temporal expression patterns of the epithelial cell adhesion molecule (EpCAM/EGP-2) in developing and adult kidneys

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

apical plasma membrane

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Spatial and temporal expression patterns of the epithelial cell adhesion molecule (EpCAM/EGP-2) in developing and adult kidneys

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

extracellular exosome

determination method or standard

IDA

3 references

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IDA

retrieved

26 September 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IDA

retrieved

26 September 2017

stated in

Intestinal epithelial cells secrete exosome-like vesicles

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IDA

integral component of plasma membrane

determination method or standard

IBA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16422&geneProductId=UniProtKB:P16422

determination method or standard

IBA

bicellular tight junction

determination method or standard

IBA

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

retrieved

8 April 2019

stated in

The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IBA

extracellular exosome

determination method or standard

HDA

2 references

retrieved

8 April 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

HDA

retrieved

8 April 2019

stated in

Intestinal epithelial cells secrete exosome-like vesicles

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

HDA

biological process

ureteric bud development

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

positive regulation of cell motility

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

negative regulation of cell-cell adhesion mediated by cadherin

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

signal transduction involved in regulation of gene expression

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Nuclear signalling by tumour-associated antigen EpCAM

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IMP

negative regulation of apoptotic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

stem cell differentiation

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IMP

positive regulation of cell population proliferation

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

positive regulation of stem cell proliferation

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IMP

positive regulation of transcription by RNA polymerase II

determination method or standard

IDA

2 references

retrieved

8 April 2019

stated in

The tumour-associated antigen EpCAM upregulates the fatty acid binding protein E-FABP

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

retrieved

8 April 2019

stated in

The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation

GOA

curator

UniProt

UniProt protein ID

P16422

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IDA

leukocyte migration

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

TAS

cell-cell adhesion via plasma-membrane adhesion molecules

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16422

determination method or standard

IEA

Gene Atlas image

PBB GE TACSTD1 201839 s at fs.png
732 × 530; 11 KB

0 references

has part(s)

Thyroglobulin type-1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P16422

Identifiers

MeSH descriptor ID

D000071858

subject named as

Epithelial Cell Adhesion Molecule

0 references

MeSH tree code

D12.776.395.550.200.263

0 references

D12.776.543.550.200.263

0 references

D23.050.285.357

0 references

D23.050.301.350.263

0 references

D09.400.430.890.200.263

0 references

RefSeq protein ID

NP_002345

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

4072

UniProt protein ID

P16422

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P16422

Ensembl protein ID

ENSP00000263735

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000263735

ENSP00000385476

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000385476

ENSP00000389028

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000389028

ENSP00000410675

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000410675

Freebase ID

/m/03gwry5

0 references

Microsoft Academic ID

2776677690

0 references

OpenAlex ID

C2776677690

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

4MZV

1 reference

stated in

UniProt

UniProt protein ID

P16422

retrieved

4 August 2016

language of work or name

English

UMLS CUI

C1704265

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(7 entries)

edit

• arwiki جزىء الالتصاق بالخلية الظهارية
• dewiki Epitheliales Zelladhäsionsmolekül
• enwiki Epithelial cell adhesion molecule
• ruwiki Молекула клеточной адгезии эпителия
• ttwiki EPCAM
• ukwiki EPCAM
• zhwiki 上皮细胞黏附分子

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q5383694&oldid=2159724382"