Keys is an English surname. Notable people with the surname include:
- Alicia Keys (born 1981), American musician
- Ancel Keys (1904–2004), American nutritionist
- Bobby Keys (1943–2014), American saxophonist
- Carleth Keys, Venezuelan journalist
- Clement Keys (1864–1937), English football manager
- Clement Melville Keys (1876–1952), American financier
- Constance Keys (1886–1964), Australian nurse
- David Keys (musician), stage name of David Nicholas Robert Johnson
- David Keys, British archaeological journalist
- Derek Keys (1931–2018), South African politician
- Jack Keys (1865–1890), English footballer
- John Keys (born 1956), British organist
- Karen Keys-Gamarra, American politician from Virginia
- Howard Keys (1935–1971), American football player
- Madison Keys (born 1995), American tennis player
- Richard Keys (born 1957), English sports presenter
- Ronald Keys (born 1945), U.S. Air Force general
- Samuel Keys (1771–1850), English china painter
- Samuel J. Keys (1847–1924), American politician and businessman
- William Keys (disambiguation)
Fictional characters
edit- Patty Keys, a character in Ninjago