Dominic Kwiatkowski
Dominic Kwiatkowski | |
|---|---|
 Kwiatkowski in 2018 | |
| Born | Dominic P. Kwiatkowski 25 May 1953 Hammersmith, London, England |
| Died | 27 April 2023 (aged 69) |
| Scientific career | |
| Fields | Genomics Malaria[1][2] |
| Institutions | Wellcome Sanger Institute University of Cambridge University of Oxford Guy's Hospital Leyland Motors[3] |
| Website | sanger |
Dominic Kwiatkowski (25 May 1953 – 27 April 2023) was an English medical researcher and geneticist who was head of the parasites and microbes programme at the Wellcome Sanger Institute[3] in Cambridge and a Professor of Genomics at the University of Oxford.[4] Kwiatkowski applied genomics and computational analysis to problems in infectious disease, with the aim of finding ways to reduce the burden of disease in the developing world.[4][5][6][7]
Education
[edit]Kwiatkowski trained as a paediatrician at Guy's Hospital[when?] in London.[4]
Career and research
[edit]Kwiatkowski spent several years in West Africa, where malaria causes high levels of infant mortality, and this was a major focus of his research over the past thirty years.[4] He made significant contributions to the understanding of malaria pathogenesis and genetic mechanisms of resistance to the disease.[4] He also pioneered genome-wide association studies (GWAS) in Africa and led large international collaborations to characterise the genomic diversity of parasite and mosquito populations around the world.[4] This work is yielding deep insights into the evolutionary biology of drug resistance and pesticide resistance with practical implications for disease control.[4]
In 2005 Kwiatkowski founded a data-sharing network, MalariaGEN, which has fostered productive research collaborations in more than forty malaria endemic countries, and has become a model for equitable sharing of genetic data and research capacity building in resource-poor settings.[4][1]
Death
[edit]Kwiatkowski died on 27 April 2023, at the age of 69.[8]
Awards and honours
[edit]Kwiatkowski was elected a Fellow of the Royal Society (FRS) in 2018[4] and a Fellow of the Academy of Medical Sciences (FMedSci) in 2000.[9]
References
[edit]- ^ a b Hill, Adrian V. S.; Allsopp, Catherine E. M.; Kwiatkowski, Dominic; Anstey, Nicholas M.; Twumasi, Patrick; Rowe, Pamela A.; Bennett, Stephen; Brewster, David; McMichael, Andrew J.; Greenwood, Brian M. (1991). "Common West African HLA antigens are associated with protection from severe malaria". Nature. 352 (6336): 595–600. Bibcode:1991Natur.352..595H. doi:10.1038/352595a0. ISSN 0028-0836. PMID 1865923.
- ^ Kwiatkowski, Dominic P. (2005). "How malaria has affected the human genome and what human genetics can teach us about malaria". American Journal of Human Genetics. 77 (2): 171–92. doi:10.1086/432519. PMC 1224522. PMID 16001361.
- ^ a b "Kwiatkowski, Dominic". Sanger.ac.uk.
- ^ a b c d e f g h i Anon (2018). "Professor Dominic Kwiatkowski FMedSci FRS". Royalsociety.org. London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
- ^ "Professor Dominic Kwiatkowski - Nuffield Department of Medicine". Ndm.ox.ac.uk.
- ^ Dominic Kwiatkowski publications from Europe PubMed Central
- ^ Robinson, T.; Campino, S. G.; Auburn, S.; Assefa, S. A.; Polley, S. D.; Manske, M.; MacInnis, B.; Rockett, K. A.; Maslen, G. L.; Sanders, M.; Quail, M. A.; Chiodini, P. L.; Kwiatkowski, D. P.; Clark, T. G.; Sutherland, C. J. (2011). "Drug-Resistant Genotypes and Multi-Clonality in Plasmodium falciparum Analysed by Direct Genome Sequencing from Peripheral Blood of Malaria Patients". PLOS ONE. 6 (8): e23204. Bibcode:2011PLoSO...623204R. doi:10.1371/journal.pone.0023204. PMC 3154926. PMID 21853089.
- ^ Ferry, Georgina (16 May 2023). "Dominic Kwiatkowski obituary". The Guardian. Retrieved 16 May 2023.
- ^ "Professor Dominic Kwiatkowski - The Academy of Medical Sciences". Acmedsci.ac.uk. Retrieved 5 February 2019.
This article incorporates text available under the CC BY 4.0 license.
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