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Protein-coding gene in the species Homo sapiens
Microtubule-associated protein RP/EB family member 3 is a protein that in humans is encoded by the MAPRE3 gene .[ 5] [ 6]
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene .[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000084764 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029166 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Renner C, Pfitzenmeier JP, Gerlach K, Held G, Ohnesorge S, Sahin U, Bauer S, Pfreundschuh M (Aug 1997). "RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells" . J Immunol . 159 (3): 1276–83. doi :10.4049/jimmunol.159.3.1276 PMID 9233623 . S2CID 23797920 . ^ a b "Entrez Gene: MAPRE3 microtubule-associated protein, RP/EB family, member 3" .
Juwana JP, Henderikx P, Mischo A, et al. (1999). "EB/RP gene family encodes tubulin binding proteins" . Int. J. Cancer . 81 (2): 275–84. doi :10.1002/(SICI)1097-0215(19990412)81:2<275::AID-IJC18>3.0.CO;2-Z PMID 10188731 . S2CID 33232892 . Nakagawa H, Koyama K, Murata Y, et al. (2000). "EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue". Oncogene . 19 (2): 210–6. doi :10.1038/sj.onc.1203308 . PMID 10644998 . S2CID 2284265 . Su LK, Qi Y (2001). "Characterization of human MAPRE genes and their proteins". Genomics . 71 (2): 142–9. doi :10.1006/geno.2000.6428 . PMID 11161807 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Bu W, Su LK (2004). "Characterization of functional domains of human EB1 family proteins" . J. Biol. Chem . 278 (50): 49721–31. doi :10.1074/jbc.M306194200 PMID 14514668 . Douglas MW, Diefenbach RJ, Homa FL, et al. (2004). "Herpes simplex virus type 1 capsid protein VP26 interacts with dynein light chains RP3 and Tctex1 and plays a role in retrograde cellular transport" . J. Biol. Chem . 279 (27): 28522–30. doi :10.1074/jbc.M311671200 PMID 15117959 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, et al. (2005). "CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex" . J. Cell Biol . 168 (1): 141–53. doi :10.1083/jcb.200405094 . PMC 2171674 PMID 15631994 . Yeh TY, Chuang JZ, Sung CH (2005). "Dynein light chain rp3 acts as a nuclear matrix-associated transcriptional modulator in a dynein-independent pathway" . J. Cell Sci . 118 (Pt 15): 3431–43. doi :10.1242/jcs.02472 PMID 16079286 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
