(Q55368961)

English

Butein Inhibited In Vitro Hexokinase-2-Mediated Tumor Glycolysis in Hepatocellular Carcinoma by Blocking Epidermal Growth Factor Receptor (EGFR).

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

Butein Inhibited In Vitro Hexokinase-2-Mediated Tumor Glycolysis in Hepatocellular Carcinoma by Blocking Epidermal Growth Factor Receptor (EGFR). (English)

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

author name string

Weirong Liao

1

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

Jingtian Liu

2

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

Dawei Zhang

3

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

Wenhai Huang

4

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

Runhao Chen

5

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

publication date

19 May 2018

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

Medical Science Monitor

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

24

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

3283-3292

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Cancer Metabolism: Fueling More than Just Growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

18F-FDG PET/CT Can Predict Survival of Advanced Hepatocellular Carcinoma Patients: A Multicenter Retrospective Cohort Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Butein inhibits cell proliferation and induces cell cycle arrest in acute lymphoblastic leukemia via FOXO3a/p27kip1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Kaempferol inhibits cell proliferation and glycolysis in esophagus squamous cell carcinoma via targeting EGFR signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Butein Shows Cytotoxic Effects and Induces Apoptosis in Human Ovarian Cancer Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

The mitochondrial voltage-dependent anion channel 1 in tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Inhibitory effects of butein on cancer metastasis and bioenergetic modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Butein, a novel dual inhibitor of MET and EGFR, overcomes gefitinib-resistant lung cancer growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Butein suppresses breast cancer growth by reducing a production of intracellular reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Tumor glycolysis as a target for cancer therapy: progress and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Aerobic glycolysis: a novel target in kidney cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Butein is a novel anti-adipogenic compound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Butein inhibits the migration and invasion of SK-HEP-1 human hepatocarcinoma cells through suppressing the ERK, JNK, p38, and uPA signaling multiple pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Hallmarks of Cancer: The Next Generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

A novel anticancer effect of butein: inhibition of invasion through the ERK1/2 and NF-kappa B signaling pathways in bladder cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Expression of type 2 hexokinase and mitochondria-related genes in gastric carcinoma tissues and cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Dietary antioxidant compounds and liver health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by butein in RAW 264.7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

10 July 2018

Butein suppresses cervical cancer growth through the PI3K/AKT/mTOR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

12 August 2018

Reduced survival of patients with hepatocellular carcinoma expressing hexokinase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987617

12 August 2018

Hepatocyte growth factor, transforming growth factor alpha, and their receptors as combined markers of prognosis in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29777095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue

1 reference

https://pubmed.ncbi.nlm.nih.gov/29777095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29777095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between FDG uptake by PET/CT and the expressions of glucose transporter type 1 and hexokinase II in cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29777095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antirestenosis effect of butein in the neointima formation progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29777095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocellular carcinoma: gender differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/29777095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-Inflammatory Activity of Butein and Luteolin Through Suppression of NFκB Activation and Induction of Heme Oxygenase-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29777095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.12659/MSM.906528

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 July 2018

http://europepmc.org/abstract/PMC/5987617

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