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David Baulcombe
David Baulcombe
Conhecido(a) por
SiRNA
Nascimento
4 de julho de 1952 (72 anos)Solihull
Nacionalidade
Britânico
Alma mater
Universidade de Leeds , Universidade de Edimburgo
Prêmios
Prêmio Wiley de Ciências Biomédicas (2003) , Prêmio Massry (2005) , Medalha Real (2006) , Medalha Benjamin Franklin (2008) , Prêmio Albert Lasker de Pesquisa Médica Básica (2008) , Prêmio Harvey (2009) , Prêmio Balzan (2012) , Prêmio Gruber de Genética (2014)
Instituições
Sainsbury Laboratory , Universidade de East Anglia , Universidade de Cambridge
Campo(s)
Genética
David Charles Baulcombe , FRS (Solihull , 4 de julho de 1952 ) é um geneticista britânico .
Foi eleito em 2001 membro da Royal Society .[ 1]
Hamilton, A; Voinnet, O; Chappell, L; Baulcombe, D (setembro de 2002). «Two classes of short interfering RNA in RNA silencing» . The EMBO journal . 21 (17): 4671–9. ISSN 0261-4189 . PMC 125409 . PMID 12198169 . doi :10.1093/emboj/cdf464
Papaefthimiou, I; Hamilton, A; Denti, M; Baulcombe, D; Tsagris, M; Tabler, M (junho de 2001). «Replicating potato spindle tuber viroid RNA is accompanied by short RNA fragments that are characteristic of post-transcriptional gene silencing» (Free full text) . Nucleic acids research . 29 (11): 2395–400. ISSN 0305-1048 . PMC 55696 . PMID 11376158 . doi :10.1093/nar/29.11.2395
Dalmay, T; Hamilton, A; Rudd, S; Angell, S; Baulcombe, DC (maio de 2000). «An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus». Cell . 101 (5): 543–53. ISSN 0092-8674 . PMID 10850496 . doi :10.1016/S0092-8674(00)80864-8
Burton, RA; Gibeaut, DM; Bacic, A; Findlay, K; Roberts, K; Hamilton, A; Baulcombe, DC; Fincher, GB (maio de 2000). «Virus-induced silencing of a plant cellulose synthase gene» (Free full text) . The Plant cell . 12 (5): 691–706. ISSN 1040-4651 . PMC 139921 . PMID 10810144 . doi :10.1105/tpc.12.5.691
Dalmay, T; Hamilton, A; Mueller, E; Baulcombe, DC (março de 2000). «Potato virus X amplicons in arabidopsis mediate genetic and epigenetic gene silencing» (Free full text) . The Plant cell . 12 (3): 369–79. ISSN 1040-4651 . PMC 139837 . PMID 10715323 . doi :10.1105/tpc.12.3.369
Jones, L; Hamilton, AJ; Voinnet, O; Thomas, CL; Maule, AJ; Baulcombe, DC (dezembro de 1999). «RNA-DNA interactions and DNA methylation in post-transcriptional gene silencing» (Free full text) . The Plant cell . 11 (12): 2291–301. ISSN 1040-4651 . PMC 144133 . PMID 10590159 . doi :10.1105/tpc.11.12.2291
Hamilton, A. J.; Baulcombe, DC (1999). «A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants». Science . 286 (5441). 950 páginas. PMID 10542148 . doi :10.1126/science.286.5441.950
Hamilton, WD; Boccara, M.; Robinson, D. J.; Baulcombe, D. C. (outubro de 1987). «The complete nucleotide sequence of tobacco rattle virus RNA-1» (Free full text) . The Journal of general virology . 68 ( Pt 10): 2563–75. ISSN 0022-1317 . PMID 3668507 . doi :10.1099/0022-1317-68-10-2563 [ligação inativa]
Boccara, M; Hamilton, WD; Baulcombe, DC (fevereiro de 1986). «The organisation and interviral homologies of genes at the 3' end of tobacco rattle virus RNA1» (Free full text) . The EMBO journal . 5 (2): 223–229. ISSN 0261-4189 . PMC 1166722 . PMID 16453668
Referências
2001: Richard Lavenham Gardner , Gabriel Horn e Samuel Edwards • 2002: Richard Peto , Suzanne Cory e Ray Freeman • 2003: John Skehel , Kenneth Langstreth Johnson e Nicholas Shackleton • 2004: James Black , Alec Jeffreys e Jack Lewis • 2005: Michael Pepper , Anthony Pawson e Michael Fisher • 2006: David Baulcombe , Richard Timothy Hunt e John Pendry • 2007: Tomas Lindahl , Cyril Hilsum e James Feast • 2008: Robert Hedges , Philip Cohen e Alan Fersht • 2009: Chintamani Rao , Ronald Laskey e Chris Dobson • 2010: Peter Knight , Azim Surani e Allen Hill • 2011: Steven Ley , Robin Holliday e Gregory Winter • 2012: Tom Kibble , Kenneth Murray e Andrew Bruce Holmes • 2013: Rodney Baxter , Walter Bodmer e Peter Neil Temple Wells • 2014: Terence Tao , Anthony Rex Hunter e Howard Morris • 2015: Jocelyn Bell Burnell , Elizabeth Blackburn e Christopher Llewellyn Smith • 2016: John Meurig Thomas , Elizabeth Robertson e John Goodby • 2017: Paul Corkum , Peter Raymond Grant , Barbara Rosemary Grant e Melvyn Greaves • 2018: Robert Stephen John Sparks , Lewis Wolpert , Shankar Balasubramanian e David Klenerman • 2019: Carol Robinson , Michel Goedert e Ann Dowling • 2020: Herbert Huppert , Caroline Dean e Ian Shanks • 2021: Colin Humphreys , Dennis Lo e Michael Green
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
1978: George Frederick Sprague , John Charles Walker · 1979: Jay Laurence Lush , Kenneth Blaxter · 1980: Karl Maramorosch · 1981: John O. Almquist , Henry A. Lardy , Glenn W. Salisbury · 1982: Wendell Lee Roelofs · 1983/4: Don Kirkham , Cornellis T. de Witt · 1984/5: Robert H. Burris · 1986: Ralph Riley , Ernest R. Sears · 1987: Theodor Otto Diener · 1988: Charles Thibault , Christopher Polge · 1989: Peter M. Biggs , Michael Elliott · 1990: Jozef Schell · 1991: Shang Fa Yang · 1993: John Edward Casida · 1994/5: Carl Barton Huffaker , Perry L. Adkisson · 1995/6: Morris Schnitzer , Frank J. Stevenson · 1996/7: Neal Lloyd First · 1998: Ilan Chet , Baldur Rosmund Stefansson · 2000: Gurdev Khush · 2001: Roger Neil Beachy , James E. Womack · 2002/3: R. Michael Roberts , Fuller W. Bazer · 2004: Yuan Longping , Steven Dale Tanksley · 2006/7: Ronald L. Phillips , Michel Georges · 2008: John Anthony Pickett , James H. Tumlinson , W. Joe Lewis · 2010: David Baulcombe · 2011: Harris A. Lewin , James R. Cook · 2013: Joachim Messing , Jared Diamond · 2014: Jorge Dubcovsky , Leif Andersson · 2015: Linda Saif · 2016: Trudy Mackay · 2018: Gene Ezia Robinson · 2019: David Zilberman · 2020: Caroline Dean
1961: Fundação Nobel •
1962: Andrei Kolmogorov , Karl von Frisch , Papa João XXIII , Paul Hindemith e Samuel Eliot Morison •
1978: Madre Teresa de Calcutá •
1979: Ernest Labrousse , Jean Piaget e Torbjörn Caspersson •
1980: Enrico Bombieri , Hassan Fathy e Jorge Luis Borges •
1981: Dan McKenzie , Frederick Vine , Josef Pieper e Paul Reuter •
1982: Jean-Baptiste Duroselle , Kenneth Vivian Thimann e Massimo Pallottino •
1983: Edward Shils , Ernst Mayr e Francesco Gabrieli •
1984: Jan Hendrik Oort , Jean Starobinski e Sewall Wright •
1985: Ernst Gombrich e Jean-Pierre Serre •
1986: Hoher Flüchtlingskommissar der Vereinten Nationen , Jean Rivero , Otto Neugebauer e Roger Revelle •
1987: Jerome Bruner , Phillip Tobias e Richard W. Southern •
1988: Michael Evenari , René Etiemble e Shmuel N. Eisenstadt •
1989: Emmanuel Levinas , Leo Pardi e Martin Rees •
1990: James Freeman Gilbert , Pierre Lalive d'Epinay e Walter Burkert •
1991: Abbé Pierre , György Ligeti , John Maynard Smith e Vitorino Magalhães Godinho •
1992: Armand Borel , Ebrahim M. Samba e Giovanni Macchia •
1993: Jean Leclant , Lothar Gall e Wolfgang H. Berger •
1994: Fred Hoyle , Martin Schwarzschild , Norberto Bobbio e René Couteaux •
1995: Alan J. Heeger , Carlo Maria Cipolla e Yves Bonnefoy •
1996: Arno Borst , Arnt Eliassen , Internationales Komitee vom Roten Kreuz e Stanley Hoffmann •
1997: Charles Gillispie , Stanley Jeyaraja Tambiah e Thomas Wilson Meade •
1998: Andrzej Walicki , Harmon Craig e Robert May •
1999: John Huxtable Elliott , Luigi Luca Cavalli-Sforza , Mikhael Gromov e Paul Ricœur •
2000: Abdul Sattar Edhi , Ilkka Hanski , Martin Litchfield West , Michael Stolleis e Michel Mayor •
2001: Claude Lorius , James Sloss Ackerman , Jean-Pierre Changeux e Marc Fumaroli •
2002: Anthony Grafton , Dominique Schnapper , Walter Gehring e Xavier Le Pichon •
2003: Eric Hobsbawm , Reinhard Genzel , Serge Moscovici e Wen-Hsiung Li •
2004: Colin Renfrew , Gemeinschaft Sant’Egidio , Michael Marmot , Nikki R. Keddie e Pierre Deligne •
2005: Lothar Ledderose , Peter Hall , Peter R. Grant , Rosemary Grant , Russel J. Hemley e Ho-kwang Mao •
2006: Ludwig Finscher , Quentin Skinner , Paolo de Bernardis , Andrew E. Lange , Elliot Meyerowitz e Christopher R. Somerville •
2007: Rosalyn Higgins , Sumio Iijima , Michel Zink , Jules Hoffmann e Karlheinz Böhm •
2008: Maurizio Calvesi , Thomas Nagel , Ian H. Frazer e Wallace S. Broecker •
2009: Terence Cave , Michael Grätzel , Brenda Milner e Paolo Rossi Monti •
2010: Manfred Brauneck , Carlo Ginzburg , Jacob Palis e Shinya Yamanaka •
2011: Peter Brown , Bronisław Baczko , Russell Lande e Joseph Silk •
2012: Ronald Dworkin , Reinhard Strohm , Kurt Lambeck e David Baulcombe •
2013: Alain Aspect , Manuel Castells , Pascale Cossart e André Vauchez •
2014: Mario Torelli , Ian Hacking , David Tilman , Dennis Sullivan e Vivre en Famille •
2015: Hans Belting , Joel Mokyr , Francis Halzen e David Karl •
2016: Piero Boitani , Reinhard Jahn e Federico Capasso