(R)-citramalat sintaza
| (R)-citramalat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.182 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
(R)-citramalat sintaza (EC 2.3.1.182, CimA) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + piruvat + H2O KoA + (2R)-2-hidroksi-2-metilbutandioat
Ovo je jedan od enzima koji učestvuju u biosintezi izoleucina kod pojednih arheja i bakterija.
Reference
[уреди | уреди извор]- ^ Howell, D.M., Xu, H. and White, R.H. (1999). „(R)-Citramalate synthase in methanogenic archaea”. J. Bacteriol. 181: 331—333. PMID 9864346.
- ^ Xu, H., Zhang, Y., Guo, X., Ren, S., Staempfli, A.A., Chiao, J., Jiang, W. and Zhao, G. (2004). „Isoleucine biosynthesis in Leptospira interrogans serotype 1ai strain 56601 proceeds via a threonine-independent pathway”. J. Bacteriol. 186: 5400—5409. PMID 15292141.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- (R)-citramalate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
