NOC2 like nucleolar associated transcriptional repressor (Q21112763)

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mammalian protein found in Homo sapiens

NOC2L
protein NOC2 homolog
nucleolar complex associated 2 homolog
nucleolar complex protein 2 homolog
NOC2L nucleolar associated transcriptional repressor
novel INHAT (inhibitor of histone acetyltransferase) repressor
novel INHAT repressor
NOC2-like protein
protein phosphatase 1, regulatory subunit 12

Language	Label	Description	Also known as
English	NOC2 like nucleolar associated transcriptional repressor	mammalian protein found in Homo sapiens	NOC2L protein NOC2 homolog nucleolar complex associated 2 homolog nucleolar complex protein 2 homolog NOC2L nucleolar associated transcriptional repressor novel INHAT (inhibitor of histone acetyltransferase) repressor novel INHAT repressor NOC2-like protein protein phosphatase 1, regulatory subunit 12

Statements

1 reference

13 November 2019

UniProt protein ID

Nucleolar complex protein 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y3T9

Armadillo-type fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y3T9

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

histone binding

determination method or standard

1 reference

26 September 2017

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

nucleosome binding

determination method or standard

1 reference

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

chromatin binding

determination method or standard

2 references

protein binding

determination method or standard

5 references

8 April 2019

Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

transcription corepressor activity

determination method or standard

1 reference

26 September 2017

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

determination method or standard

transcription corepressor activity

determination method or standard

determination method or standard

histone binding

determination method or standard

Noc1p-Noc2p complex

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

Noc2p-Noc3p complex

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

determination method or standard

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

26 September 2017

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

26 September 2017

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

determination method or standard

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

determination method or standard

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

26 September 2017

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

determination method or standard

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

biological process

cellular response to UV

determination method or standard

1 reference

8 April 2019

Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

negative regulation of B cell apoptotic process

determination method or standard

1 reference

8 April 2019

Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

negative regulation of histone acetylation

determination method or standard

1 reference

26 September 2017

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

2 references

26 September 2017

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

26 September 2017

Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y3T9&geneProductId=UniProtKB:Q9Y3T9

determination method or standard

negative regulation of intrinsic apoptotic signaling pathway

determination method or standard

1 reference

8 April 2019

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

apoptotic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

ribosomal large subunit biogenesis

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

regulation of signal transduction by p53 class mediator

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

3 references

8 April 2019

Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3T9

determination method or standard

negative regulation of histone acetylation

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000317992

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000317992

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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