Epithelial membrane protein 2 (Q21130759)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P54851

1 reference

13 November 2019

1 reference

13 November 2019

protein kinase binding

1 reference

27 March 2018

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

kinase binding

1 reference

8 April 2019

Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

protein binding

1 reference

8 April 2019

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

protein kinase binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

1 reference

8 April 2019

ISS

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

3 references

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

27 March 2018

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

Golgi membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

1 reference

8 April 2019

membrane raft

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

4 references

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

27 March 2018

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

27 March 2018

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

integral component of membrane

Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

cytosol

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

regulation of kinase activity

biological process

1 reference

8 April 2019

FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

cell death

1 reference

8 April 2019

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

regulation of glomerular filtration

1 reference

8 April 2019

Mutations in EMP2 cause childhood-onset nephrotic syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

regulation of angiogenesis

positive regulation of cell-matrix adhesion

1 reference

8 April 2019

Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

cell-matrix adhesion

1 reference

8 April 2019

Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

actin filament organization

1 reference

8 April 2019

Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

bleb assembly

1 reference

8 April 2019

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

positive regulation of cell population proliferation

1 reference

8 April 2019

Mutations in EMP2 cause childhood-onset nephrotic syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

regulation of cell-matrix adhesion

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

caveola assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

1 reference

8 April 2019

ISS

cell migration

1 reference

8 April 2019

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

regulation of endothelial cell migration

1 reference

8 April 2019

EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

activation of protein kinase activity

1 reference

8 April 2019

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

protein localization to cell surface

1 reference

8 April 2019

Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

actin-mediated cell contraction

positive regulation of integrin-mediated signaling pathway

2 references

2 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

27 March 2018

Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

regulation of vasculogenesis

1 reference

8 April 2019

EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

cell adhesion

1 reference

27 March 2018

Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54851&geneProductId=UniProtKB:P54851

blood vessel endothelial cell migration

1 reference

8 April 2019

Epithelial membrane protein 2 controls VEGF expression in ARPE-19 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

cell population proliferation

TAS

cell adhesion

positive regulation of integrin-mediated signaling pathway

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851

cell population proliferation

1 reference

8 April 2019

Retracted: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54851