Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP (Q21666110)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9990853%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

title

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP (English)

1 reference

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Beta-transducin repeat containing E3 ubiquitin protein ligase

12 December 2019

main subject

1 reference

GOA release 2020-03-11

signal transduction

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

3

Z J Chen

Z J

Chen

1 reference

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12 December 2019

E Spencer

1

E

Spencer

1 reference

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12 December 2019

J Jiang

series ordinal

2

author given names

J

author last names

Jiang

1 reference

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12 December 2019

language of work or name

English

0 references

publication date

1 February 1999

1 reference

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12 December 2019

1 reference

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12 December 2019

volume

13

1 reference

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12 December 2019

issue

3

1 reference

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12 December 2019

page(s)

284-294

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The NF-kappa B and I kappa B proteins: new discoveries and insights

12 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

19 March 2017

1 reference

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Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

19 March 2017

1 reference

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

19 March 2017

1 reference

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Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

19 March 2017

1 reference

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Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

19 March 2017

1 reference

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Ubiquitin-dependent protein degradation

19 March 2017

1 reference

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

19 March 2017

1 reference

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A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

19 March 2017

1 reference

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

19 March 2017

1 reference

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beta-catenin is a target for the ubiquitin-proteasome pathway

19 March 2017

1 reference

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A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

NF-kappa B: ten years after

7 April 2017

1 reference

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

7 April 2017

1 reference

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Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Catalysis by a multiprotein IkappaB kinase complex

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta gene

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Signaling pathways that establish the dorsal-ventral pattern of the Drosophila embryo

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Cell cycle: cull and destroy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

A versatile transcriptional effector of Wingless signaling

27 September 2017

1 reference

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slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Targeting of substrates to the 26S proteasome

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

NF-kappaB activation: the I kappaB kinase revealed?

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

30 May 2018

1 reference

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cactus, a maternal gene required for proper formation of the dorsoventral morphogen gradient in Drosophila embryos

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

The control of cell fate along the dorsal-ventral axis of the Drosophila embryo.

30 May 2018

1 reference

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Signal transduction. Docking IkappaB kinases.

30 May 2018

1 reference

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316434

Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9990853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Specificity of the ubiquitin isopeptidase in the PA700 regulatory complex of 26 S proteasomes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9990853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9990853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.13.3.284

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9990853%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9990853%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

PubMed publication ID

9990853

2 references