G9a and Glp methylate lysine 373 in the tumor suppressor p53 (Q24298004)

Euchromatic histone lysine methyltransferase 2

GOA release 2020-03-11

1 reference

peptidyl-lysine dimethylation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

7

Danny Reinberg

Danny

Reinberg

1 reference

19 October 2023

6

Thomas Jenuwein

Thomas

Jenuwein

1 reference

19 October 2023

Jing Huang

1

Jing

Huang

1 reference

19 October 2023

Jean Dorsey

2

Jean

Dorsey

1 reference

19 October 2023

Sergei Chuikov

3

Sergei

Chuikov

1 reference

19 October 2023

Laura Pérez-Burgos

4

0 references

Xinyue Zhang

5

Xinyue

Zhang

1 reference

19 October 2023

Shelley L Berger

8

Shelley L

Berger

1 reference

Journal of Biological Chemistry

19 October 2023

language of work or name

English

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publication date

26 March 2010

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published in

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volume

285

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issue

13

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page(s)

9636-41

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cites work

Acetylation is indispensable for p53 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

p53 is regulated by the lysine demethylase LSD1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Modulation of p53 function by SET8-mediated methylation at lysine 382

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Repression of p53 activity by Smyd2-mediated methylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Regulation of p53 activity through lysine methylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

ONCOMINE: a cancer microarray database and integrated data-mining platform

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

The emerging field of dynamic lysine methylation of non-histone proteins.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

Post-translational modification of p53 in tumorigenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

27 September 2017

Why is p53 acetylated?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843213

27 September 2017

Identifiers

DOI

10.1074/JBC.M109.062588

1 reference

release_6lfawwfbqzfste5gfz5who2u5e

Fatcat ID

0 references

1 reference

1 reference

1 reference