Common variants at 30 loci contribute to polygenic dyslipidemia (Q24598765)

50

0 references

Rory Edwards Collins

51

0 references

Michael Boehnke

58

0 references

Leena Peltonen-Palotie

55

0 references

David Schlessinger

46

0 references

Serena Sanna

33

0 references

Luigi Ferrucci

31

0 references

Veikko Salomaa

54

0 references

Manuela Uda

34

0 references

Sekar Kathiresan

1

0 references

Jaakko Tuomilehto

47

0 references

Paul Scheet

32

0 references

Markku Laakso

30

0 references

Olle Melander

53

0 references

Johanna Kuusisto

27

0 references

Leif Groop

49

0 references

Josée Dupuis

37

0 references

Candace Guiducci

16

0 references

Diana Zelenika

20

0 references

Mark Lathrop

52

0 references

Pilar Galan

25

0 references

Marju Orho-Melander

56

0 references

Angelo Scuteri

45

0 references

Cristen J. Willer

2

0 references

Kathryn L. Lunetta

36

0 references

Serkalem Demissie

4

0 references

José María Ordovás

57

0 references

Karen L Mohlke

60

Karen L Mohlke

0 references

Serge Hercberg

42

0 references

Anne U Jackson

13

Anne U Jackson

0 references

Heather M Stringham

24

Heather M Stringham

0 references

Lori L Bonnycastle

12

Lori L Bonnycastle

0 references

Sarah Parish

18

Sarah Parish

0 references

Edward G. Lakatta

44

Edward G Lakatta

0 references

Benjamin F. Voight

11

Benjamin F Voight

0 references

Jaspal Kooner

41

Jaspal S Kooner

0 references

Richard N. Bergman

28

Richard N Bergman

0 references

Eric E Schadt

6

Eric E Schadt

0 references

L. Adrienne Cupples

61

L Adrienne Cupples

0 references

Toshiko Tanaka

10

Toshiko Tanaka

0 references

Christopher J O'Donnell

39

Christopher J O'Donnell

0 references

Gina M Peloso

3

Gina M Peloso

0 references

Lee M Kaplan

7

Lee Kaplan

0 references

Mario A. Morken

22

Mario A Morken

0 references

Gonçalo Abecasis

59

Gonçalo R Abecasis

0 references

Pierre Meneton

43

Pierre Meneton

0 references

Derrick A Bennett

8

Derrick Bennett

0 references

Kiran Musunuru

5

Kiran Musunuru

0 references

Aarti Surti

15

Aarti Surti

0 references

Kari A Kubalanza

21

Kari A Kubalanza

0 references

Laura Scott

23

Laura J Scott

0 references

Paul I W de Bakker

38

Paul I W de Bakker

0 references

Yun Li

9

Yun Li

0 references

Amy J Swift

26

Amy J Swift

0 references

author name string

Gabriel Crawford

14

0 references

Noel P Burtt

17

0 references

Robert Clarke

19

0 references

Jouko Sundvall

29

0 references

Qiong Yang

35

0 references

John C Chambers

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

40

0 references

language of work or name

English

0 references

publication date

January 2009

0 references

number of pages

10

0 references

published in

Nature Genetics

0 references

volume

41

0 references

issue

1

0 references

page(s)

56-65

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Control of pancreas and liver gene expression by HNF transcription factors

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

A molecular defect causing fish eye disease: an amino acid exchange in lecithin-cholesterol acyltransferase (LCAT) leads to the selective loss of alpha-LCAT activity

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Mapping the genetic architecture of gene expression in human liver

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Low-density lipoprotein receptor-related protein interacts with MafB, a regulator of hindbrain development

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

ATP binding cassette transporter G5 and G8 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

24 March 2017

1 reference

Crossref

https://api.crossref.org/works/10.1038/NG.291

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

A HapMap harvest of insights into the genetics of common disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

LDL-cholesterol concentrations: a genome-wide association study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Identification of Tim4 as a phosphatidylserine receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-density lipoprotein cholesterol.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham Study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Increased prebeta-high density lipoprotein, apolipoprotein AI, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Studies on the mechanism of fatty acid synthesis. XVI. Preparation and general properties of acyl-malonyl acyl carrier protein-condensing enzyme from Escherichia coli

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

Polymorphisms associated with cholesterol and risk of cardiovascular events

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

A Polymorphism in the Protease-Like Domain of Apolipoprotein(a) Is Associated With Severe Coronary Artery Disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: Design, Recruitment, and Initial Examination

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881676

ISIS-3: a randomised comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41,299 cases of suspected acute myocardial infarction. ISIS-3 (Third International Study of Infarct S

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19060906

12 December 2020

The private hepatocyte nuclear factor-1alpha G319S variant is associated with plasma lipoprotein variation in Canadian Oji-Cree

1 reference

https://pubmed.ncbi.nlm.nih.gov/19060906

12 December 2020

Cardiovascular risk factor changes in Finland, 1972-1997

1 reference

https://pubmed.ncbi.nlm.nih.gov/19060906

12 December 2020

An investigation of coronary heart disease in families. The Framingham offspring study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19060906

12 December 2020

Extensions to pedigree analysis. IV. Covariance components models for multivariate traits

1 reference

https://pubmed.ncbi.nlm.nih.gov/19060906

12 December 2020

Reduction of plasma lipids, lipoproteins, and apoproteins by dietary fish oils in patients with hypertriglyceridemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19060906

12 December 2020

The Malmo Diet and Cancer Study. Design and feasibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/19060906

12 December 2020

Identifiers

DOI

10.1038/NG.291

1 reference

Dimensions Publication ID

1044117587

0 references

1 reference

1 reference

PubMed publication ID

19060906

1 reference