p300/MDM2 complexes participate in MDM2-mediated p53 degradation (Q28288274)

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6 December 2019

title

p300/MDM2 complexes participate in MDM2-mediated p53 degradation (English)

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6 December 2019

8

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6 December 2019

author name string

S R Grossman

1

1 reference

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6 December 2019

M Perez

2

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6 December 2019

A L Kung

3

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6 December 2019

M Joseph

4

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6 December 2019

C Mansur

5

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6 December 2019

Z X Xiao

6

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6 December 2019

S Kumar

7

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6 December 2019

D M Livingston

9

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6 December 2019

language of work or name

English

0 references

publication date

1 October 1998

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6 December 2019

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6 December 2019

volume

2

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6 December 2019

issue

4

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6 December 2019

page(s)

405-415

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An essential role for p300/CBP in the cellular response to hypoxia

6 December 2019

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The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300.

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7 January 2021

Recruitment of p300/CBP in p53-dependent signal pathways

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7 January 2021

Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells

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7 January 2021

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

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High-efficiency transformation of mammalian cells by plasmid DNA

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7 January 2021

Mapping of the p53 and mdm-2 Interaction Domains

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7 January 2021

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

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7 January 2021

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

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7 January 2021

Association of p300 and CBP with simian virus 40 large T antigen

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7 January 2021

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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7 January 2021

Synergistic activation of transcription by CBP and p53

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Roles of ubiquitin-mediated proteolysis in cell cycle control

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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7 January 2021

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

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7 January 2021

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

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7 January 2021

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

Transcription factor-specific requirements for coactivators and their acetyltransferase functions

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Binding and modulation of p53 by p300/CBP coactivators

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7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

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7 January 2021

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

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7 January 2021

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

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7 January 2021

The transcriptional coactivators p300 and CBP are histone acetyltransferases

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7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

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7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

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7 January 2021

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

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7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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7 January 2021

Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting region

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7 January 2021

Steroid receptor coactivator-1 is a histone acetyltransferase

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7 January 2021

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

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7 January 2021

Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function

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7 January 2021

The p53-mdm-2 autoregulatory feedback loop

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7 January 2021

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

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7 January 2021

The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

1 reference

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7 January 2021

Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

1 reference

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7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

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7 January 2021

10.1016/S1097-2765(00)80140-9

Identifiers

DOI

1 reference

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6 December 2019

1 reference