Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function (Q34015423)

30 July 2017

title

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function (English)

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30 July 2017

6

Julien Sage

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30 July 2017

7

Tyler Jacks

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30 July 2017

Annemieke de Vries

1

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30 July 2017

Elsa R Flores

2

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30 July 2017

Barbara Miranda

3

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30 July 2017

Harn-Mei Hsieh

4

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30 July 2017

Conny Th M van Oostrom

5

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30 July 2017

language of work or name

English

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publication date

26 February 2002

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30 July 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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30 July 2017

volume

99

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30 July 2017

issue

5

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30 July 2017

page(s)

2948-2953

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High metastatic potential in mice inheriting a targeted p53 missense mutation

30 July 2017

cites work

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The role of p53 in tumour suppression: lessons from mouse models

5 July 2018

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pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

5 July 2018

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Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.

5 July 2018

1 reference

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p53, the cellular gatekeeper for growth and division

5 July 2018

1 reference

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Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system

5 July 2018

1 reference

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Mutations in the p53 and SCID genes cooperate in tumorigenesis.

5 July 2018

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p53 in growth control and neoplasia

5 July 2018

1 reference

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5 July 2018

p53: puzzle and paradigm

1 reference

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RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

5 July 2018

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p53 is required for radiation-induced apoptosis in mouse thymocytes

5 July 2018

1 reference

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Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

5 July 2018

1 reference

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Tumor spectrum analysis in p53-mutant mice

5 July 2018

1 reference

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p53 and the Li-Fraumeni syndrome

5 July 2018

1 reference

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Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage.

5 July 2018

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Tumor suppressor p53: analysis of wild-type and mutant p53 complexes

5 July 2018

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p53 mutations in human cancers

5 July 2018

1 reference

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Oncogenic forms of p53 inhibit p53-regulated gene expression

5 July 2018

1 reference

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

5 July 2018

1 reference

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

5 July 2018

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Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

29 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/11867759

12 December 2020

p53 status and the efficacy of cancer therapy in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11867759

12 December 2020

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11867759

12 December 2020

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/11867759

12 December 2020

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11867759

12 December 2020

Identifiers

DOI

10.1073/PNAS.052713099

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30 July 2017

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30 July 2017

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