Core domain interactions in full-length p53 in solution (Q34479332)

2 August 2017

title

Core domain interactions in full-length p53 in solution (English)

1 reference

identical protein binding

2 August 2017

1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

8

Alan R Fersht

1 reference

2 August 2017

Dmitry B Veprintsev

1

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author name string

Stefan M V Freund

2

1 reference

2 August 2017

Antonina Andreeva

3

1 reference

2 August 2017

Stacey E Rutledge

4

1 reference

2 August 2017

Henning Tidow

5

1 reference

2 August 2017

José Manuel Pérez Cañadillas

6

1 reference

2 August 2017

Caroline M Blair

7

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2 August 2017

language of work or name

English

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publication date

6 February 2006

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Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

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2 August 2017

volume

103

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2 August 2017

issue

7

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2 August 2017

page(s)

2115-2119

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NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

The N-terminal domain of p53 is natively unfolded.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

A graph-theory algorithm for rapid protein side-chain prediction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Live or let die: the cell's response to p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Modeling multi-component protein-DNA complexes: the role of bending and dimerization in the complex of p53 dimers with DNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

6 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Identification of an additional negative regulatory region for p53 sequence-specific DNA binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

NMR-based discovery of lead inhibitors that block DNA binding of the human papillomavirus E2 protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Modelling protein docking using shape complementarity, electrostatics and biochemical information

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Architectural accommodation in the complex of four p53 DNA binding domain peptides with the p21/waf1/cip1 DNA response element

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Refined solution structure of the oligomerization domain of the tumour suppressor p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Solution structure of the tetrameric minimum transforming domain of p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Presence of a potent transcription activating sequence in the p53 protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

A transcriptionally active DNA-binding site for human p53 protein complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Definition of a consensus binding site for p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511130103

Regulation of DNA binding of p53 by its C-terminal domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511130103

Cooperative binding of tetrameric p53 to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511130103

Use of pair potentials across protein interfaces in screening predicted docked complexes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413758

Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511130103

Latent and active p53 are identical in conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511130103

Assignment of 1H(N), 15N, 13C(alpha), 13CO and 13C(beta) resonances in a 67 kDa p53 dimer using 4D-TROSY NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511130103

Recognition of DNA by p53 Core Domain and Location of Intermolecular Contacts of Cooperative Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511130103

The C-terminus of p53: the more you learn the less you know

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16461914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NMR spectroscopy reveals the solution dimerization interface of p53 core domains bound to their consensus DNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16461914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16461914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0511130103

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference