Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein (Q34649008)

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English	Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1 reference

based on heuristic

inferred from title

Nigel Mark Hooper

object named as

Nigel M Hooper

4

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author name string

Joanna M Cordy

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Ishrut Hussain

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Colin Dingwall

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Anthony J Turner

5

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Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

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publication date

22 September 2003

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Europe PubMed Central

PubMed publication ID

3 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

3 August 2017

100

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

11735-11740

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Brain membrane cholesterol domains, aging and amyloid beta-peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.1635130100

21 January 2018

Lipid rafts and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

A fluid connection: cholesterol and Abeta

1 reference

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7 July 2018

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

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7 July 2018

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Statins and the risk of dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Replacement of the transmembrane anchor in angiotensin I-converting enzyme (ACE) with a glycosylphosphatidylinositol tail affects activation of the B2 bradykinin receptor by ACE inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae (review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins

1 reference

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7 July 2018

The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells

1 reference

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7 July 2018

Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

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7 July 2018

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

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7 July 2018

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

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7 July 2018

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208827

7 July 2018

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1 reference

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7 July 2018

Elevated low-density lipoprotein in Alzheimer's disease correlates with brain abeta 1-42 levels

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1635130100

21 January 2018

Characterization of detergent-insoluble complexes containing the familial Alzheimer's disease-associated presenilins

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1635130100

21 January 2018

Identifiers

10.1073/PNAS.1635130100

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2003PNAS..10011735C

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10.1073/PNAS.1635130100

0 references

Dimensions Publication ID

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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