Adrenomedullin (Q366935)

1 reference

8 April 2019

Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

adrenomedullin receptor binding

1 reference

23 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

protein binding

IPI

1 reference

23 May 2017

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

adrenomedullin receptor binding

IPI

3 references

cytoplasm

1 reference

8 April 2019

Effects of endothelin-1 on release of adrenomedullin and C-type natriuretic peptide from individual human vascular endothelial cells

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

negative regulation of cell population proliferation

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

neural tube closure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

branching involved in labyrinthine layer morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

antibacterial humoral response

1 reference

23 May 2017

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

defense response to Gram-negative bacterium

1 reference

23 May 2017

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

receptor internalization

3 references

8 April 2019

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

8 April 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

8 April 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

blood circulation

1 reference

1 January 2018

Genomic structure of human adrenomedullin gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35318&geneProductId=UniProtKB:P35318

signal transduction

1 reference

8 April 2019

Expression of adrenomedullin by human granulosa lutein cells and its effect on progesterone production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

animal organ regeneration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

cell-cell signaling

1 reference

1 January 2018

Genomic structure of human adrenomedullin gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35318&geneProductId=UniProtKB:P35318

response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

vascular associated smooth muscle cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

defense response to Gram-positive bacterium

1 reference

23 May 2017

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

positive regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

vasculogenesis

1 reference

8 April 2019

Gene silencing of human RAMP2 mediated by short-interfering RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

negative regulation of vasoconstriction

1 reference

8 April 2019

Effect of adrenomedullin on the production of endothelin-1 and on its vasoconstrictor action in resistance arteries: evidence for a receptor-specific functional interaction in patients with heart failure

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

G protein-coupled receptor internalization

1 reference

8 April 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

cAMP-mediated signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

calcium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

response to starvation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

heart development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

regulation of the force of heart contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

positive regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

response to yeast

1 reference

23 May 2017

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

response to cold

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

positive regulation of vasculogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

neuron projection regeneration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

hormone secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

antifungal humoral response

1 reference

23 May 2017

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

response to glucocorticoid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

developmental growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

ageing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

progesterone biosynthetic process

1 reference

1 January 2018

Expression of adrenomedullin by human granulosa lutein cells and its effect on progesterone production

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35318&geneProductId=UniProtKB:P35318

negative regulation of vascular permeability

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

androgen metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

response to insulin

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

positive regulation of angiogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

response to organic substance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

odontogenesis of dentin-containing tooth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

spongiotrophoblast layer development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

cAMP biosynthetic process

antimicrobial humoral immune response mediated by antimicrobial peptide

1 reference

23 May 2017

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35318

regulation of systemic arterial blood pressure

1 reference

8 April 2019

Central and peripheral cardiovascular actions of adrenomedullin 5, a novel member of the calcitonin gene-related peptide family, in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

positive regulation of heart rate

regulation of urine volume

1 reference

8 April 2019

Central and peripheral cardiovascular actions of adrenomedullin 5, a novel member of the calcitonin gene-related peptide family, in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

cAMP biosynthetic process

1 reference

1 January 2018

Genomic structure of human adrenomedullin gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35318&geneProductId=UniProtKB:P35318

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

1 reference

8 April 2019

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

IGI

8 April 2019

Central and peripheral cardiovascular actions of adrenomedullin 5, a novel member of the calcitonin gene-related peptide family, in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

8 April 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

8 April 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

amylin receptor signaling pathway

IGI

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

adrenomedullin receptor signaling pathway

IGI

3 references

8 April 2019

Central and peripheral cardiovascular actions of adrenomedullin 5, a novel member of the calcitonin gene-related peptide family, in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

8 April 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

8 April 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

inflammatory response

1 reference

8 April 2019

Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

female pregnancy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

response to wounding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318

positive regulation of progesterone biosynthetic process

1 reference

8 April 2019

Expression of adrenomedullin by human granulosa lutein cells and its effect on progesterone production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35318