The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells (Q40749592)

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scientific article published on November 2000

Language	Label	Description	Also known as
English	The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells	scientific article published on November 2000

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

1 reference

based on heuristic

inferred from title

rhabdomyosarcoma

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

author name string

Xu Q

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

language of work or name

0 references

publication date

1 November 2000

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

275

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

47

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

36750-36757

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal.

1 reference

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21 January 2018

Defining the regulatory networks for muscle development.

1 reference

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21 January 2018

Skeletal muscle determination and differentiation: story of a core regulatory network and its context

1 reference

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21 January 2018

Muscle differentiation: more complexity to the network of myogenic regulators.

1 reference

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21 January 2018

Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

1 reference

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21 January 2018

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

1 reference

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21 January 2018

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

1 reference

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21 January 2018

Myogenin gene disruption results in perinatal lethality because of severe muscle defect

1 reference

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21 January 2018

Mapping of myogenin transcription during embryogenesis using transgenes linked to the myogenin control region

1 reference

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21 January 2018

The regulation of myogenin gene expression during the embryonic development of the mouse

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2

1 reference

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21 January 2018

The Role of the CANNTG Promoter Element (E box) and the Myocyte-enhancer-binding-factor-2 (MEF-2) Site in the Transcriptional Regulation of the Chick Myogenin Gene

1 reference

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21 January 2018

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

1 reference

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21 January 2018

IGF-I is required for normal embryonic growth in mice

1 reference

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21 January 2018

Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts

1 reference

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21 January 2018

Proliferation precedes differentiation in IGF-I-stimulated myogenesis

1 reference

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21 January 2018

Insulin-like growth factor-I stimulates terminal myogenic differentiation by induction of myogenin gene expression

1 reference

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21 January 2018

Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Mechanism of activation and function of protein kinase B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Signalling through phosphoinositide 3-kinases: the lipids take centre stage

1 reference

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21 January 2018

Ribosomal S6 kinase signaling and the control of translation

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells

1 reference

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21 January 2018

An essential role of phosphatidylinositol 3-kinase in myogenic differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Rhabdomyosarcoma--working out the pathways

1 reference

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21 January 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

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21 January 2018

p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps

1 reference

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21 January 2018

Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases

1 reference

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21 January 2018

MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005030200

21 January 2018

Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: dominant negative p85 expression blocks differentiation of L6E9 muscle cells

1 reference

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21 January 2018

Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2

1 reference

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21 January 2018

From insect eye to vertebrate muscle: redeployment of a regulatory network

1 reference

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21 January 2018

Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation

1 reference

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Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya

1 reference

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21 January 2018

p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription

1 reference

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21 January 2018

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C

1 reference

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21 January 2018

TPA-induced differentiation of human rhabdomyosarcoma cells: expression of the myogenic regulatory factors.

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M005030200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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