Identification of the Actinomycin D Biosynthetic Pathway from Marine-Derived Streptomyces costaricanus SCSIO ZS0073. (Q64979927)

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12 April 2020

title

Identification of the Actinomycin D Biosynthetic Pathway from Marine-Derived Streptomyces costaricanus SCSIO ZS0073 (English)

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12 April 2020

main subject

Streptomyces parvulus

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Streptomyces sindenensis

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Streptomyces flavovirens

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Streptomyces lividans

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Streptomyces heliomycini

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Streptomyces mutabilis

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Streptomyces flavogriseus

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Streptomyces chrysomallus

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Streptomyces costaricanus

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Streptomyces anthocyanicus

Streptomyces violascens

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1 reference

1 reference

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Streptomyces anulatus

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7

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author name string

Mengchan Liu

1

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Yanxi Jia

2

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Yunchang Xie

3

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12 April 2020

Chunyan Zhang

4

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12 April 2020

Junying Ma

5

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Changli Sun

6

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12 April 2020

publication date

23 April 2019

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full work available at URL

12 April 2020

https://www.mdpi.com/1660-3397/17/4/240/pdf?version=1555998684

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19 March 2024

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published in

Marine Drugs

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volume

17

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issue

4

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Creative Commons Attribution 4.0 International

12 April 2020

copyright license

start time

23 April 2019

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April 2022 Public Data File from Crossref

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access restriction status

open access

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inferred from online access status

cites work

Actinomycin synthesis in Streptomyces antibioticus. Purification and properties of a 3-hydroxyanthranilate 4-methyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Molecular cloning and in vitro expression of a silent phenoxazinone synthase gene from Streptomyces lividans

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Biosynthesis of the actinomycin chromophore: incorporation of 3-hydroxy-4-methylanthranilic acid into actinomycins by Streptomyces antibioticus

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Treatment of tumor-bearing dogs with actinomycin D

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Sequence-specific actinomycin D binding to single-stranded DNA inhibits HIV reverse transcriptase and other polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Molecular characterization of the genes of actinomycin synthetase I and of a 4-methyl-3-hydroxyanthranilic acid carrier protein involved in the assembly of the acylpeptide chain of actinomycin in Streptomyces

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Actinomycin production persists in a strain of Streptomyces antibioticus lacking phenoxazinone synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Construction and in vitro analysis of a new bi-modular polypeptide synthetase for synthesis of N-methylated acyl peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Enterovirus infection and activation of human umbilical vein endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

The TetR family of transcriptional repressors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Quorum sensing: cell-to-cell communication in bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Structure of Phenoxazinone Synthase fromStreptomyces antibioticusReveals a New Type 2 Copper Center†,‡

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/31018504

1 reference

12 December 2020

Actinomycins with altered threonine units in the beta-peptidolactone

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Evolution of gamma-butyrolactone synthases and receptors in Streptomyces

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

First Y-type actinomycins from Streptomyces with divergent structure-activity relationships for antibacterial and cytotoxic properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Specific activation of the p53 pathway by low dose actinomycin D: a new route to p53 based cyclotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

The actinomycin biosynthetic gene cluster of Streptomyces chrysomallus: a genetic hall of mirrors for synthesis of a molecule with mirror symmetry

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Genomics and the ancient origins of the daptomycin biosynthetic gene cluster

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

MbtH-Like Proteins as Integral Components of Bacterial Nonribosomal Peptide Synthetases

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Aromatic C-methyltransferases with antipodal stereoselectivity for structurally diverse phenolic amino acids catalyze the methylation step in the biosynthesis of the actinomycin chromophore

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

N-acylation during glidobactin biosynthesis by the tridomain nonribosomal peptide synthetase module GlbF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

A marine-derived Streptomyces sp. MS449 produces high yield of actinomycin X2 and actinomycin D with potent anti-tuberculosis activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Methylated actinomycin D, a novel actinomycin D analog induces apoptosis in HepG2 cells through Fas- and mitochondria-mediated pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Antibacterial and Cytotoxic Actinomycins Y6-Y9 and Zp from Streptomyces sp. Strain Gö-GS12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Actinomycin D Down-regulates SOX2 Expression and Induces Death in Breast Cancer Stem Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Genetic interrelations in the actinomycin biosynthetic gene clusters of Streptomyces antibioticus IMRU 3720 and Streptomyces chrysomallus ATCC11523, producers of actinomycin X and actinomycin C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Neo-actinomycins A and B, natural actinomycins bearing the 5H-oxazolo[4,5-b]phenoxazine chromophore, from the marine-derived Streptomyces sp. IMB094.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Identification, Bioactivity, and Productivity of Actinomycins from the Marine-Derived Streptomyces heliomycini

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

A Novel TetR Family Transcriptional Regulator, CalR3, Negatively Controls Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Ketonization of Proline Residues in the Peptide Chains of Actinomycins by a 4-Oxoproline Synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

A new actinomycin Z analogue with an additional oxygen bridge between chromophore and β-depsipentapeptide from Streptomyces sp. KIB-H714.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31018504

12 December 2020

Actinomycin. Chemistry and mechanism of action

1 reference

12 April 2024

https://opencitations.net/index/api/v1/references/10.3390/MD17040240

Anti-MRSA actinomycins D1-D4 from the marine sponge-associated Streptomyces sp. LHW52447

1 reference

12 April 2024

https://opencitations.net/index/api/v1/references/10.3390/MD17040240

Systematic Trial for Evaluating Docetaxel in a Human Prostate Cancer Cell DU145 Xenograft Model.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/references/10.3390/MD17040240

Biosynthesis of the Actinomycin Chromophore: Incorporation of 3-Hydroxy-4-Methylanthranilic Acid into Actinomycins by Streptomyces antibioticus

2 references

12 April 2024

https://opencitations.net/index/api/v1/references/10.3390/MD17040240

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.100.2.977-984.1969

Identifiers

DOI

10.3390/MD17040240

1 reference

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12 April 2020

1 reference

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12 April 2020

PubMed publication ID

31018504

1 reference